JAK-2 Mutation (CMPD) (V617F) ,Real-Time PCR in Lucknow

What Does a JAK2 Mutation Test Measure in Lucknow?

The test measures:

• Presence or absence of the JAK2 V617F mutation, the most common mutation in MPNs.
• Mutation type (heterozygous or homozygous), which influences disease behaviour.
• Abnormal blood cell production activity linked to bone marrow disorders.

If the V617F mutation is not detected, additional tests like JAK2 Exon 12, CALR, or MPL may be advised.

JAK2 Mutation Test: Who Needs It and Why It’s Done

Who Should Get a JAK2 Mutation Test?

Your doctor may recommend a JAK2 Mutation Test in Lucknow if you have:

• Unusually high red blood cell, platelet, or white blood cell counts.
• Symptoms such as fatigue, headaches, dizziness, or unexplained weight loss.
• Enlarged spleen or frequent blood clot formation.
• Suspected bone marrow disorders or abnormal blood reports.
• Recurrent or unexplained thrombosis (blood clots), especially in unusual sites.

Why is a JAK2 Mutation Test Done?

What is the Purpose of a JAK2 Mutation Test?

The JAK2 Mutation Test is performed to:

• Confirm or rule out myeloproliferative neoplasms (MPNs).
• Differentiate MPNs from reactive blood count elevations.
• Assess the risk of thrombotic complications.
• Help plan targeted therapy using JAK inhibitors.
• Track disease progression or response to treatment.

JAK2 Mutation Test Booking & Reports – Metropolis Healthcare

How to Book JAK2 Mutation Test with Metropolis Healthcare in Lucknow?

1. Book Online
   Visit the Metropolis Healthcare website or app and select the JAK2 Mutation Test in Lucknow.
2. Choose a Collection Option
   Opt for convenient home sample collection or visit your nearest Metropolis Lab in Lucknow.
3. Sample Collection
   A phlebotomist collects 3 ml of EDTA blood under sterile conditions.
4. Laboratory Testing
   The test is performed using Real-Time PCR (RT-PCR) in NABL & CAP accredited labs.
5. Reports
   Access your results within 24 hours via email, WhatsApp, or the Metropolis app.

Is Home Sample Collection Available for the JAK2 Mutation Test in Lucknow?

Yes. Metropolis Healthcare offers home sample collection for the JAK2 Mutation Test in Lucknow. Our skilled phlebotomists ensure a smooth, hygienic collection process, making testing comfortable and convenient for you.

In how much time will I get JAK2 Mutation Test report?

Reports are generally available the next day once the sample reaches the laboratory.
Note: Reporting time may vary depending on your location and sample logistics.

Where can I see or get JAK2 Mutation Test results?

Your results can be viewed on the Metropolis Healthcare website or mobile app. Reports are also shared via email or WhatsApp, and printed copies can be collected from any Metropolis Lab in Lucknow.

Guide to Interpreting JAK2 Mutation Test Results

What Your JAK2 Mutation Test Results May Indicate

What Preparations Are Needed for a JAK2 Mutation Test?

This test is easy and requires no fasting or special preparation:

• No fasting required — eat and drink as usual before the test.
• Avoid contamination — ensure the sample is properly labelled.
• Provide your complete medical history, including any previous blood test results.
• Inform your doctor about ongoing treatments, especially if you are on chemotherapy or immunotherapy.

JAK2 Mutation Test Price in Different Cities

The cost of a JAK2 Mutation Test may vary depending on your location. Here's a table showing the approximate price range for the JAK2 Mutation Test at Metropolis Healthcare in major Indian cities:

The JAK2 Mutation Test cost may vary depending on the city and the specific tests included in the panel. However, Metropolis Healthcare offers competitive JAK2 Mutation Test prices across major cities in India.

References

1. Lee H.J. et al. (2012). Clinical significance of JAK2 V617F mutation in myeloproliferative neoplasms. Clinical Cancer Research, 18(22):7001–7010. PMID: 23209034
2. Ha J.S. et al. (2012). JAK2 mutations in myeloproliferative disorders: Diagnostic and prognostic implications. Ann Lab Med, 32(6):385–391. PMCID: PMC3486931
3. Indian Council of Medical Research. (2010). JAK2 mutation analysis in polycythaemia and thrombocythaemia patients. Indian J Med Res, 132:423–427.
4. Baxter E.J. et al. (2005). Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet, 365(9464):1054–1061. PMID: 15781101
5. Kralovics R. et al. (2005). A gain-of-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med, 352(17):1779–1790. PMID: 15858187