What does HLA cross-match by Flow cytometry measure?

HLA cross-match by flow cytometry measures the surface markers present on your immune cells called human leucocyte antigens (HLA) that help identify self-cells from foreign cells.

Why is HLA cross-match by Flow cytometry done?

• To assess the compatibility of a donor's and recipient's immune system before an organ transplantation • To monitor the effectiveness of immunosuppressive therapy after a transplant • To detect and diagnose autoimmune disorders like diabetes, rheumatoid arthritis, celiac disease, etc. • To investigate transfusion reactions, when blood products can trigger an adverse immune response

When is HLA cross-match recommended and who should take the test?

Your doctor may recommend this test if you • are scheduled for an organ transplant, • have symptoms or a family history of autoimmune disorders, or • experience transfusion reactions or complications after blood transfusions.

What if the results of the HLA cross-match are abnormal?

The results of the HLA cross-match can be either compatible or incompatible between the donor and recipient. If it's incompatible, it may result in the rejection of an organ transplant or immune-mediated complications.

What to expect during the HLA cross-match?

• Blood samples will be collected from both the recipient and donor. • The samples will be processed in the laboratory through flow cytometry.

What preparations are required before the HLA cross-match?

• Avoid medications that can interfere with your test results. • Inform your doctor if you have any specific requirements.

What other tests may be ordered with HLA cross-match?

• Complete Blood Count (CBC) • Serum creatinine levels • Liver function tests • Additional HLA testing, such as HLA typing

What is the HLA cross-match by Flow cytometry also known as?

Histocompatibility testing or HLA compatibility testing

What is organ transplantation?

Organ transplantation is a surgical procedure where an organ from one person (donor) is transplanted into another person's (recipient) body to replace a damaged or diseased organ. Common examples include liver, kidney, heart, lungs or pancreas transplants.

HLA Cross-match by Flow Cytometry in Kolkata

Also known as: HLA - T & B Cell Cross Match, Heparin Blood and Serum

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Overview

HLA cross match by Flow cytometry is a diagnostic test used in the context of organ transplantation to assess compatibility between the recipient and potential donor. It involves analyzing the interaction between the recipient's antibodies and the donor's human leukocyte antigens (HLA) expressed on the surface of cells. Flow cytometry utilizes fluorescently labeled antibodies that bind to specific HLA antigens. By analyzing the fluorescence patterns, the test determines if there is a mismatch and detects the presence of pre-formed antibodies in the recipient's blood that could lead to organ rejection. This information is crucial for transplant teams in making decisions about donor suitability and managing the risk of immune-mediated complications post-transplantation.

HLA - T & B Cell Cross Match, Heparin Blood and Serum Price in Kolkata

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the HLA - T & B Cell Cross Match, Heparin Blood and Serum with a clear pricing structure

The price of HLA - T & B Cell Cross Match, Heparin Blood and Serum in Kolkata is ₹ 7,100

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