CK7 IHC

This test measures the levels of the protein CK7 in tissue samples. CK7 is a useful marker that helps pathologists differentiate between different types of multiorgan carcinomas.

• The CK7 IHC test detects the presence of primary biliary cirrhosis.
• It is also useful in distinguishing between prostate cancer and transitional cell carcinomas.
• To help determine the appropriate treatment plan for patients with multiorgan carcinomas
• To provide additional information for narrowing down the differential diagnosis of various types of cancer

• When a patient has been diagnosed with multiorgan carcinomas and further information is needed to determine the origin and nature of the cancer cells.
• When there is uncertainty regarding the type and origin of cancer cells, especially in cases where multiple organs are involved.
• When other diagnostic tests have not provided conclusive results and further investigation is required.

Abnormal results may indicate the presence of particular types of cancers or help in ruling out certain types. However, abnormal results alone are not diagnostic and should be interpreted by a qualified healthcare professional in combination with other clinical findings.

During the IHC single marker with reporting CK7 test:

• A small tissue sample is taken from the affected organ or area.
• The sample is prepared and stained with specific antibodies to identify CK7.
• The prepared sample is analysed under a microscope to determine the presence or absence of CK7.

• You may need to provide your original histopathology report and other relevant clinical and radiological details.
• Follow any fasting or medication instructions given by your healthcare provider.
• Inform your doctor about any allergies or medical conditions that may affect the test.

• Immunohistochemistry (IHC) panels for additional markers to aid in cancer diagnosis.
• Molecular testing, such as genetic sequencing or tumour profiling, to identify specific genetic alterations in cancer cells

• Cytokeratin 7 immunohistochemistry
• CK7 IHC

Transitional cell carcinoma (TCC), also known as urothelial carcinoma, is a type of cancer that can occur in various parts of the urinary system. The urinary system includes the kidneys, ureters (tubes that connect the kidneys to the bladder), bladder, and urethra. Transitional cells are specialized cells that line the inside of these structures. TCC most commonly affects the bladder, but it can also occur in the renal pelvis (the part of the kidney that collects urine), ureters, and urethra. The term "transitional" refers to the ability of these cells to change shape, allowing the tissue to stretch as the bladder fills with urine.