Haemophilia Profile

The "Haemophilia Profile" is a specialized set of tests used for screening, diagnosing, and monitoring coagulation disorders, specifically focusing on haemophilia, which is a genetic bleeding disorder characterized by deficiencies in clotting factors, particularly Factor VIII (8) for Hemophilia A and Factor IX (9) for Hemophilia B. The profile typically includes the following key components: APTT (Activated Partial Thromboplastin Time): This test measures the time it takes for blood to clot in response to specific activators. It is sensitive to deficiencies in clotting factors, particularly Factors VIII and IX, and can help identify possible bleeding disorders. Factor VIII: This test measures the level of Factor VIII in the blood. Low levels or absence of Factor VIII is indicative of Hemophilia A, which is the most common form of haemophilia. Factor IX: This test measures the level of Factor IX in the blood. Reduced or absent Factor IX levels indicate Hemophilia B, also known as Christmas disease. The Haemophilia Profile is essential for diagnosing and monitoring patients suspected of having hemophilia. Early detection is crucial to initiate appropriate management and treatment strategies, which often include replacement therapies with clotting factor concentrates to prevent or control bleeding episodes. Regular monitoring of clotting factor levels helps ensure that patients with hemophilia receive appropriate and timely care to prevent complications associated with bleeding disorders. Additionally, genetic testing may also be conducted to confirm the specific type of hemophilia and to assess the inheritance pattern.