Chromogranin A (CGA) Test - Serum

Chromogranin A Test Overview

The Chromogranin A test, often referred to as the CgA test, is a diagnostic tool used to measure the level of Chromogranin A protein in the blood. Chromogranin A is a secretory protein found in the dense-core vesicles of neuroendocrine cells, which possess both nerve and hormone-producing properties. These specialised cells are present in various organs, including the pancreas, gastrointestinal tract, and lungs, and can give rise to a range of benign and malignant tumours.

The CgA test is particularly valuable in diagnosing and monitoring neuroendocrine tumours (NETs). It helps assess disease progression, evaluate the effectiveness of treatment, and detect tumour recurrence after surgery. By providing critical insights into the presence and activity of neuroendocrine cells, the CgA test aids healthcare professionals in managing and tailoring treatment strategies for patients with neuroendocrine disorders.

Chromogranin A (CgA) test measures the amount of chromogranin A in the blood.

Chromogranin A (CgA) is a protein that is produced by cells in the endocrine system, including cells in the pancreas, adrenal glands, and other organs. CgA is often measured in the blood as a marker of neuroendocrine tumors, which are rare tumors that can develop in a variety of organs.

Chromogranin-A, Plasma test is typically ordered to help diagnose and monitor neuroendocrine tumors, a type of rare cancer that can develop in various organs of the body, including the pancreas, lungs, and digestive system. The Chromogranin A, Plasma test may be ordered by a healthcare provider if a person is suspected of having a neuroendocrine tumor, or if they have been diagnosed with a neuroendocrine tumor and their healthcare provider wants to monitor the tumor's growth or response to treatment. The test may also be ordered if a person has symptoms that suggest a neuroendocrine tumor, such as flushing, diarrhea, or abdominal pain.

Associated Tests:

5-HIAA, Urine 24 hrs by column chromatography

Insulin (Fasting) Serum

C-Peptide Post prandial, Serum

C-Peptide, Random, Serum

Glucagon

Gastrin Serum

ACTH Adreno Corticotropic Hormone - Plasma

Written by: Supriya Kulkarni, Lead-Content & Training