Amino Acid - Quantitative, EDTA Plasma

Amino Acid Profile Overview

Amino acids in plasma are vital for protein synthesis and various metabolic processes. Imbalances in their levels may signal metabolic disorders. Monitoring plasma amino acids aids in diagnosing and managing conditions impacting protein metabolism and overall health.

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a powerful technique for precisely measuring the amounts of individual amino acids in a sample. It offers several advantages over traditional methods. LC-MS/MS separates amino acids using liquid chromatography, then identifies and quantifies them with high sensitivity using mass spectrometry. This allows for the detection of a wider range of amino acids, including those that are difficult to derivatize, and minimizes interference from other molecules in the sample.

The amino acid profile is a diagnostic test that measures amino acid levels in the body, which are vital for protein synthesis, hormones, and enzymes. It analyses blood, urine, or tissue samples to assess essential and non-essential amino acids, helping maintain health and detect metabolic disorders. Used by healthcare professionals, it evaluates nutritional status, diagnoses genetic issues, and monitors liver or kidney conditions. Research explores amino acid roles and needs. This test supports personalised healthcare by offering detailed insights for targeted interventions and promoting better health outcomes and understanding of biological processes.