Alkaline Phosphatase Isoenzymes Electrophoresis, Serum

Alkaline Phosphatase Isoenzymes Electrophoresis Serum Test Overview

Alkaline phosphatase is an enzyme found in various tissues throughout the body, including the liver, bone, and intestines. The Alkaline Phosphatase Isoenzymes Electrophoresis - Serum test is a diagnostic procedure used to separate and measure the various isoenzymes of alkaline phosphatase in a patient's blood serum. Measuring its isoenzymes can help pinpoint the source of elevated alkaline phosphatase levels in the blood.

The Alkaline Phosphatase Isoenzymes Electrophoresis Serum test is a diagnostic tool that measures the different forms (isoenzymes) of the enzyme alkaline phosphatase (ALP) present in the blood. ALP is an enzyme found in various tissues throughout the body, with the highest concentrations in the liver, bones, kidneys, and intestines. Each tissue produces a slightly different version of ALP, known as isoenzymes.

This test helps identify which specific isoenzyme is elevated, allowing clinicians to determine which tissue or organ is likely affected. It is essential for differential diagnosis, especially when trying to determine if the source of elevation is hepatic (from the liver) or osseous (from the bones). 

The Alkaline Phosphatase Isoenzymes Electrophoresis Serum test can also be used to screen for, monitor, or help diagnose liver and biliary diseases, bone disorders, and other health conditions such as hepatitis, hyperparathyroidism, hyperthyroidism, and certain types of cancer.