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Galactomannan Test
Also known as: Galactomannan, Aspergillus Antigen Test by EIA – Serum
No special precautions
Sample Type
Blood
Recommended for
Male, Female
Report
Within 24 Hours
Blood test at Home
NABL & CAP Accredited Labs
Accurate & Quality Test Reports
Trusted by Leading Doctors & Hospitals
Galactomannan, Aspergillus Antigen Test by EIA – Serum Details in Brief
| Also Known As | Aspergillus Antigen Test, GM Test, Serum Galactomannan Test |
|---|---|
| Purpose | To detect invasive aspergillosis and monitor antifungal therapy effectiveness in immunocompromised patients |
| Preparation | No special preparation required |
| Fasting | Fasting not required |
| Reporting Time | Same day |
| Cost | 6,480 |
What is a Galactomannan Test?
The Galactomannan test is a specialised blood test that detects the presence of galactomannan, a component of the Aspergillus fungal cell wall, in your bloodstream. This test helps identify invasive aspergillosis, a serious fungal infection that primarily affects people with weakened immune systems such as those undergoing chemotherapy, stem cell transplants, or organ transplants.
By detecting the infection early, the test allows doctors to begin antifungal treatment promptly, preventing severe complications.
What Does a Galactomannan Test Measure?
The Galactomannan test measures the amount of Aspergillus antigen (galactomannan) in your blood using the Enzyme Immunoassay (EIA) technique. It provides important clinical insights:
- Early Detection of Invasive Aspergillosis: Identifies infection before it becomes severe.
- Therapeutic Monitoring: Evaluates how well antifungal treatment is working.
- Prognostic Evaluation: Persistent galactomannan levels may suggest ongoing infection.
- Differential Diagnosis: Helps distinguish fungal infections from bacterial or viral causes.
- Screening in High-Risk Patients: Detects fungal infection in immunocompromised patients before symptoms occur.
Galactomannan Test: Who Needs It and Why It’s Done
What Symptoms May Call for a Galactomannan Test?
Your doctor may recommend this test if you experience any of the following, especially if you have a weakened immune system:
- Persistent fever unresponsive to antibiotics
- Cough, chest pain, or breathing difficulty
- Weight loss or fatigue without clear cause
- Abnormal lung findings on CT or X-ray
Who Should Get a Galactomannan Test?
This test is particularly important for:
- Patients undergoing chemotherapy for blood cancers likeleukaemia
- Organ or bone marrow transplant recipients
- People with prolonged neutropenia (low white blood cell counts)
- Individuals on long-term corticosteroid or immunosuppressive therapy
- Patients showing unexplained fever or respiratory infection symptoms
Why is a Galactomannan Test Done?
The test helps in early diagnosis of invasive aspergillosis and guides timely antifungal therapy. It also assists in monitoring treatment response and detecting possible recurrence.
Importance of a Galactomannan Test
The Galactomannan test is critical in the management of fungal infections in immunocompromised individuals. Early detection significantly improves treatment success and survival rates. The test can identify Aspergillus infection before severe symptoms appear, helping your doctor make timely therapeutic decisions and avoid unnecessary broad-spectrum antibiotic use.
Galactomannan Test Booking & Reports – Metropolis Healthcare
How to Book the Galactomannan Test and Get Your Reports?
- Simple Online Booking
Book the Galactomannan Test easily through the Metropolis Healthcare website or app. Choose your preferred slot for home collection or visit your nearest Metropolis Lab. - Safe Home Sample Collection
Our phlebotomists collect your sample safely from home following all hygiene and infection control standards. - Sample Tracking Updates
Track your sample at every stage directly through the Metropolis Healthcare website. - Accurate Laboratory Testing
Your sample is analysed in NABL & CAP accredited laboratories using advanced Enzyme Immunoassay (EIA) technology. - Quick & Easy Reports
Receive your reports on the same day via email, WhatsApp, or download them from the Metropolis Healthcare website or app.
Is Home Sample Collection for Galactomannan Test Available Near You?
Yes, Metropolis Healthcare offers home collection for the Galactomannan Test. A trained phlebotomist visits your home at your convenience to collect the sample safely and comfortably.
In How Much Time Will I Get the Galactomannan Test Report?
Reports are generally available on the same day once the sample reaches the lab.
Note: Reporting time may vary based on your location.
Where Can I See or Get Galactomannan Test Results?
You can view your results on the Metropolis Healthcare website or app. Reports are also shared via email or WhatsApp, and a printed copy can be collected from your nearest Metropolis Lab.
Interpreting Galactomannan Test Results
What Your Galactomannan Test Results May Indicate
|
Parameter |
Normal Range |
High Values May Indicate |
Low Values May Indicate |
|
Galactomannan |
Negative: <0.50 Index |
Positive: ≥ 0.50 Index |
Presence of invasive aspergillosis or other fungal infection |
Understanding Abnormal Galactomannan Test Results by Parameter
|
Parameter |
High Value Interpretation |
Low Value Interpretation |
|
Galactomannan |
May suggest active Aspergillus infection, particularly in immunocompromised patients |
Indicates absence of fungal infection or effective antifungal therapy |
How Should You Prepare for a Galactomannan Test?
To ensure accurate results, follow these steps before the test:
- Fasting not required: You can eat and drink as usual before the test.
- Medication disclosure: Inform your doctor about all antibiotics or antifungal medications you are currently taking.
- Clinical history: Provide details of recent infections, transplants, or chemotherapy.
- Avoid contamination: Ensure no food particles (like cereals or pasta) are consumed immediately before the test as they may cause false positives.
- Regular testing: If you are at high risk, your doctor may recommend testing twice a week for close monitoring.
How Is a Galactomannan Test Done? (Step-by-Step Procedure)
The Galactomannan test is performed using a simple blood collection process:
- Preparation: A tourniquet is tied around your arm to make veins more visible.
- Cleaning: The puncture site is cleaned with antiseptic.
- Sample Collection: A sterile needle is used to draw about 3 ml of blood into a gel vacutainer.
- Completion: The needle is removed, and a bandage is applied.
- Processing: The sample is tested using Enzyme Immunoassay (EIA) to detect galactomannan antigen levels.
Conditions That May Affect Galactomannan Test Accuracy
Certain factors can cause false results or affect test reliability:
- Antibiotic interference: Drugs like Piperacillin/Tazobactam or Amoxicillin/Clavulanic acid may cause false positives.
- Dietary influence: Recent consumption of cereals, milk formulas, or pasta may affect readings.
- Concurrent antifungal therapy: Ongoing antifungal medications may reduce antigen detection sensitivity.
- Cross-reactivity: Other molds such as Penicillium or Alternaria can produce false positives.
- Timing of testing: Early or infrequent sampling may miss antigen peaks; high-risk patients should be tested twice weekly.
Diseases That a Galactomannan Test Can Help Detect
The Galactomannan test is primarily used to detect and monitor:
- Invasive aspergillosis
- Aspergillus lung infection (pulmonary aspergillosis)
- Fungal infections in immunocompromised patients
- Aspergillosis in transplant recipients
- Systemic fungal infections in patients with blood cancers
Galactomannan Test Price in Different Cities
The cost of a Galactomannan Test may vary depending on your location. Here's a table showing the approximate price range for the Galactomannan Test at Metropolis Healthcare in major Indian cities:
|
City |
Approximate Cost (INR) |
|
₹ 5700 to ₹ 6850 |
|
|
₹ 5700 to ₹ 6850 |
|
|
₹ 5700 to ₹ 6850 |
|
|
₹ 5700 to ₹ 6850 |
The Galactomannan Test cost may vary depending on the city and the specific tests included in the panel. However, Metropolis Healthcare offers competitive Galactomannan Test prices across major cities in India.
References
- Maertens, J., et al. (2002). Galactomannan antigen detection for diagnosis of invasive aspergillosis. Clinical Infectious Diseases, 35(3), 368–376. PMID: 12145724
- Pfeiffer, C.D., et al. (2006). Diagnostic performance of galactomannan assay for invasive aspergillosis. Clinical Infectious Diseases, 42(10), 1417–1427. PMID: 16619154
- Duarte, R.F., et al. (2014). Serum galactomannan-based early detection of invasive aspergillosis in hematology patients. Haematologica, 99(9), 1508–1515. PMID: 24881017
- Marr, K.A., et al. (2012). Antifungal therapy monitoring using serum galactomannan testing. Clinical Microbiology Reviews, 25(3), 450–463. PMID: 22763633
- Cordonnier, C., et al. (2015). Impact of mold-active antifungal therapy on galactomannan detection. Clinical Microbiology and Infection, 21(2), 190–196. PMID: 25627209
Galactomannan, Aspergillus Antigen Test by EIA – Serum Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Galactomannan, Aspergillus Antigen Test by EIA – Serum with a clear pricing structure.
The Galactomannan, Aspergillus Antigen Test by EIA – Serum Price in Aurangabad is ₹ 6,480 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
It detects galactomannan, a substance from Aspergillus fungus, to diagnose invasive aspergillosis.
It is recommended for patients with weak immune systems, such as transplant recipients or those undergoing chemotherapy.
Fasting not required; you can eat and drink normally before your sample is collected.
A small blood sample is drawn from your vein and analysed using Enzyme Immunoassay (EIA).
High levels suggest an active Aspergillus infection, especially in immunocompromised patients.
Yes, antibiotics such as Piperacillin/Tazobactam may cause false positives, while antifungals may reduce sensitivity.
High-risk patients are often tested twice weekly for early detection of fungal infections.
Yes, eating cereals, milk formulas, or pasta before testing can sometimes cause false positives.
Yes, Metropolis Healthcare offers home sample collection for the Galactomannan Test.
A negative test does not completely rule out infection; your doctor may repeat the test or use additional diagnostic methods.
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Why Metropolis?
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We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
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