Creatinine Clearance Test 24 Hour Urine

The Creatinine Clearance Test measures the levels of creatinine in a 24-hour urine sample and a serum sample collected at the same time.

The Creatinine Clearance Test is useful in the following situations:

• Identifying kidney damage or disease in individuals with chronic kidney disease (CKD).
• Evaluating the progression of kidney disease.
• Assessing the impact of medications or treatments on kidney function.
• Adjusting drug dosages for patients with compromised kidney function.
• Determining the suitability of kidney transplant recipients or donors.

The Creatinine Clearance Test may be recommended in various clinical scenarios, such as:

• Evaluation of Kidney Function: The test may be ordered if there are symptoms or signs suggesting kidney problems, such as changes in urinary patterns, swelling, or high blood pressure.
• Chronic Conditions: People with chronic conditions such as diabetes or hypertension, which can potentially impact kidney function, may be advised to undergo regular creatinine clearance tests.
• Kidney Disease Monitoring: Individuals with known kidney disease may undergo creatinine clearance testing regularly to monitor the progression of the disease and assess the effectiveness of treatment.
• Medication Monitoring: Some medications can have adverse effects on the kidneys. Individuals taking medications that are known to affect kidney function may have creatinine clearance tests as part of routine monitoring.
• Preoperative Assessment: In some cases, a creatinine clearance test may be performed before certain medical procedures or surgeries to ensure that the kidneys are functioning adequately.

The results of the Creatinine Clearance Test provide an estimate of the glomerular filtration rate (GFR), which is a measure of kidney function. Lower GFR values suggest reduced kidney function, which may indicate the presence of kidney disease or damage. Higher GFR values are typically associated with better kidney function.

• The Creatinine Clearance Test involves collecting urine over 24 hours and a blood sample.
• On the day of the test, you will begin by emptying your bladder and discarding that first void.
• Then, for the next 24 hours, you will need to collect all urine in a provided container.
• Store the container in a cool place, like a refrigerator, during the collection period.
• On the following day, provide the collected urine sample to the healthcare provider or laboratory for analysis.

Before the test, patients may be advised to:

• Refrain from strenuous exercise and maintain a usual diet.
• Stay well-hydrated throughout the 24-hour collection period.
• Avoid certain medications or supplements that can affect creatinine levels, but only do so under the guidance of a healthcare provider.

• 24-hour urine volume, age (date of birth preferred), height, and weight required

Additional tests that may be ordered alongside the Creatinine Clearance Test include:

• Serum creatinine test: A blood test to measure the concentration of creatinine in the blood.
• Urinalysis: To assess the overall health of the urinary tract and detect the presence of other substances in the urine.
• Renal imaging studies (e.g., ultrasound or CT scans): To visualize the structure of the kidneys and detect any abnormalities.

• 24-Hour Urine Test