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CD19 Test
Also known as: CD19 Count, EDTA Blood
No special precautions
Sample Type
Blood
Recommended for
Male, Female
Report
Within 48 Hours
Blood test at Home
NABL & CAP Accredited Labs
Accurate & Quality Test Reports
Trusted by Leading Doctors & Hospitals
CD19 Count, EDTA Blood Details in Brief
| Also Known As | CD19 Count, B-Cell Marker Test, B-Lymphocyte Count |
|---|---|
| Purpose | To evaluate B-cell populations, diagnose B-cell leukemias and lymphomas, and assess immune system function |
| Preparation | No special preparation required |
| Fasting | Fasting not required |
| Reporting Time | Same day |
| Cost | 2,945 |
What Is a CD19 Test?
The CD19 Test is a blood test that measures the presence and quantity of CD19 proteins on B-cells, a type of white blood cell responsible for producing antibodies and supporting immune function.
CD19 acts as a marker to identify B-cells in your blood or bone marrow. This test is performed using Flow Cytometry, an advanced technique that uses lasers to analyse and count cells expressing CD19.
Doctors use this test to diagnose and monitor B-cell related cancers such as leukemia and lymphoma, evaluate autoimmune conditions, and assess immune deficiencies.
What Does a CD19 Test Measure?
The CD19 Test helps evaluate your immune system and detect disorders that affect B-cells. It measures:
- CD19 Cells (%): The percentage of B-cells among total lymphocytes.
- CD19 Absolute Count: The number of CD19-positive cells per microlitre of blood.
- B-cell Function: Helps determine if your immune system can produce adequate antibodies.
- Treatment Response: Monitors B-cell depletion after immunotherapy or bone marrow transplant.
CD19 Test: Who Needs It and Why It’s Done
What Symptoms May Call for a CD19 Test?
Your doctor may suggest a CD19 Test if you experience:
- Recurrent or unusual infections suggesting low immunity
- Enlarged lymph nodes, liver, or spleen
- Fatigue, night sweats, or unexplained weight loss
- Swelling or tenderness in lymph areas
- Symptoms suggestive of leukemia, lymphoma, or autoimmune disease
Who Should Get a CD19 Test?
This test is typically recommended for:
- Patients suspected of B-cell cancers such as chronic lymphocytic leukemia (CLL), acute lymphoblastic leukemia (ALL), or lymphomas
- Individuals with suspected immune deficiency disorders
- Patients undergoing monoclonal antibody therapies (like Rituximab) to monitor B-cell depletion
- Individuals being evaluated for autoimmune conditions such as lupus or rheumatoid arthritis
- Post-transplant patients for immune reconstitution monitoring
Why Is a CD19 Test Done?
The CD19 Test helps in diagnosing and monitoring disorders that affect B-cell populations. It provides insight into how well your immune system is functioning and helps doctors tailor therapy for blood cancers and autoimmune diseases.
Importance of a CD19 Test
The CD19 Test is vital in both diagnosis and treatment monitoring of immune and blood-related conditions. By identifying B-cell abnormalities, it assists doctors in confirming cancers like leukemia and lymphoma, monitoring therapy response, and tracking immune reconstitution after immunosuppressive treatment.
It is also crucial for evaluating patients receiving B-cell depletion therapies, ensuring that the treatment is effectively targeting abnormal cells.
CD19 Test Booking & Reports – Metropolis Healthcare
How to Book the CD19 Test and Get Your Reports
- Simple Online Booking
Book your CD19 Test easily through the Metropolis Healthcare website or App. Choose your test, select a convenient slot, and schedule home sample collection. You can also visit your nearest Metropolis Lab. - Safe Home Sample Collection
Our expert phlebotomists collect your blood sample safely from home, following strict hygiene standards for accuracy and comfort. - Sample Tracking Updates
Track your sample status through the Metropolis Healthcare website from collection to testing. - Accurate Laboratory Testing
Your sample is processed at NABL & CAP accredited Metropolis Labs using Flow Cytometry, ensuring highly precise and reliable cell analysis. - Quick & Easy Reports
Reports are usually available on the same day through email, WhatsApp, or can be downloaded from the Metropolis Healthcare website or App.
Is Home Sample Collection for CD19 Test Available Near You?
Yes. Metropolis Healthcare offers home sample collection for the CD19 Test. Our trained staff ensures safe, hygienic, and convenient sample collection at your preferred time and location.
How Long Does It Take to Get a CD19 Test Report?
Reports are typically available on the same day once the sample reaches the Lab.
Note: Reporting time may vary depending on your location.
Where Can I See or Get CD19 Test Results?
CD19 Test results can be accessed through multiple convenient channels. You can log in to the Metropolis Healthcare website or App to view and download your report, or receive it via email or WhatsApp. Physical copies are also available at your nearest Metropolis Lab.
Interpreting CD19 Test Results
What Your CD19 Test Results May Indicate
| Parameter | Normal Range | Interpretation |
|---|---|---|
| % CD19 Cells | 4.6 – 22.1% | Indicates the percentage of B-cells among total lymphocytes. |
| CD19 Absolute Count | 56.6 – 417.4 cells/μL | Reflects the total number of CD19-positive cells in your blood. Low counts may suggest immune deficiency, while high counts can indicate lymphoma or leukemia. |
Understanding Abnormal CD19 Test Results by Parameter
| Result Type | Possible Indications |
|---|---|
| Low CD19 Count | Primary or secondary immunodeficiency, post-therapy B-cell depletion, or bone marrow suppression. |
| High CD19 Count | B-cell lymphoproliferative disorders like CLL, ALL, or non-Hodgkin lymphoma. |
| Normal CD19 Count with Symptoms | May indicate early or localized disease; further diagnostic tests (e.g., bone marrow biopsy) may be required. |
How Should You Prepare for a CD19 Test?
- No fasting required: You can eat and drink normally before the test.
- Medication disclosure: Inform your doctor if you are on immunosuppressive drugs or receiving monoclonal antibody therapy.
- Stay hydrated: Drinking water before testing makes vein access easier.
- Avoid testing during infection: Active infections can temporarily alter lymphocyte counts.
How Is a CD19 Test Done? (Step-by-Step Procedure)
- Preparation: A tourniquet is tied around your arm to make veins more visible.
- Cleaning: The puncture site is cleaned with an antiseptic.
- Sample Collection: About 3 ml of blood is drawn into an EDTA vacutainer.
- Completion: The needle is removed, and a small bandage is applied.
- Processing: The sample is analysed using Flow Cytometry to count CD19-positive cells and determine their proportion among lymphocytes.
Conditions That May Affect CD19 Test Accuracy
Several patient-related factors may influence your test results:
- Recent infections: Viral or bacterial infections can temporarily raise lymphocyte counts.
- Medications: Immunosuppressive or chemotherapy drugs may lower CD19 cell levels.
- Autoimmune disorders: Can cause abnormal fluctuations in B-cell counts.
- Recent immunotherapy: Treatments targeting B-cells (like Rituximab) can reduce CD19 cell counts for months.
- Age and stress: Natural variations in lymphocyte levels may occur with ageing or prolonged stress.
Diseases That a CD19 Test Can Help Detect
- Chronic Lymphocytic Leukemia (CLL)
- Acute Lymphoblastic Leukemia (ALL)
- Non-Hodgkin Lymphoma
- Common Variable Immunodeficiency (CVID)
- Systemic Lupus Erythematosus (SLE)
- Rheumatoid Arthritis
- B-cell Depletion from Targeted Therapy (e.g., Rituximab)
CD19 Test Price in Different Cities
The cost of a CD19 Test may vary depending on your location. Here's a table showing the approximate price range for the CD19 Test at Metropolis Healthcare in major Indian cities:
|
City |
Approximate Cost (INR) |
|
₹ 2,400 to ₹ 3,000 |
|
|
₹ 2,400 to ₹ 3,000 |
|
|
₹ 2,400 to ₹ 3,000 |
|
|
₹ 2,400 to ₹ 3,000 |
The CD19 Test cost may vary depending on the city and the specific tests included in the panel. However, Metropolis Healthcare offers competitive CD19 Test prices across major cities in India.
References
- Nadler, L. M., Stashenko, P., Hardy, R., et al. (1983). Serotherapy of a patient with a monoclonal antibody directed against B cells. New England Journal of Medicine, 309(6), 307–314. PMID: 6409380
- Wang, K., et al. (2019). CD19: A biomarker for B cell malignancies and immunotherapies. Journal of Hematology & Oncology, 12(1), 100. PMID: 31409214
- Scheuermann, R. H., & Racila, E. (1995). CD19 antigen in leukemia and lymphoma diagnosis and immunotherapy. Blood, 85(8), 1991–2004. PMID: 7718876
- Kraus, H., et al. (2021). Flow cytometry in the diagnosis of hematologic malignancies. Frontiers in Immunology, 12, 717. PMID: 34421892
- Maecker, H. T., & Trotter, J. (2006). Flow cytometry controls, instrument setup, and the determination of positivity. Cytometry Part A, 69A(9), 1037–1042. PMID: 16906542
CD19 Count, EDTA Blood Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the CD19 Count, EDTA Blood with a clear pricing structure.
The CD19 Count, EDTA Blood Price in Rajkot is ₹ 2,945 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
It measures the presence and number of B-cells (CD19-positive lymphocytes) in your blood to assess immune health and detect disorders.
It helps detect and monitor B-cell cancers such as leukemia and lymphoma, and assess response to treatment.
No, fasting is not required. You can eat and drink normally before your test.
Low CD19 counts may indicate immunodeficiency or B-cell depletion from therapy.
Yes, recent infections can temporarily increase B-cell counts and may affect interpretation.
The test is performed using Flow Cytometry, which analyses CD19-positive cells with high precision.
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We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
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