CD19

CD19 testing measures the levels of CD19. It helps in evaluating the functioning and activity of B cells, which are essential for a healthy immune system.

• To diagnose and monitor conditions affecting B cell activity such as primary immunodeficiencies.
• To evaluate the effectiveness of treatment for B cell disorders.
• To assess the risk of developing certain autoimmune diseases.
• To monitor response to therapy in patients with B cell malignancies.
• To aid in the diagnosis of certain types of leukemia and lymphoma.

CD19 testing may be recommended if you:

• Have symptoms or a family history suggestive of immune system disorders
• Have been diagnosed with B cell disorders or cancers
• Are undergoing treatment for B cell-related conditions
• Are at risk for developing certain autoimmune diseases
• Require monitoring of your immune system function

The normal range for CD19 levels may vary depending on age, gender, and individual factors. Abnormal results may indicate:

• Decreased levels: Reduced B cell activity, immunodeficiency, or treatment failure
• Increased levels: Chronic lymphocytic leukemia, lymphoma, or certain autoimmune diseases

Discuss your test results with your doctor who will interpret them in conjunction with your medical history and other diagnostic tests.

During the CD19 test:

• A small sample of your blood will be drawn.
• The sample will be sent to the laboratory for analysis.
• The test is conducted using a technique called flow cytometry, which analyses the cells in your blood sample.
• The process is quick and relatively painless, with minimal discomfort.

Before the CD19 test:

• No special preparations are usually required.
• Inform your doctor about any medications or supplements you are taking as they may affect the results.
• Follow any specific instructions given by your doctor regarding fasting or other requirements.

Other tests that may be ordered alongside CD19 include:

• Immunoglobulin testing: To assess immunoglobulin levels in the blood.
• B cell subset analysis: To evaluate the distribution and function of different B cell populations.
• Genetic testing: To identify specific gene mutations related to B cell disorders.

Pan B Cell marker

B cell-related dysfunction refers to conditions where B cells, a type of white blood cell, do not function properly. This can lead to abnormal immune responses, increased vulnerability to infections, and an increased risk of certain cancers such as leukemia and lymphoma.