CTX Test - Beta-2-Crosslaps CTx-1 Plasma

• Elevated levels of these markers in the blood can indicate increased bone resorption, which may be associated with conditions such as

• Osteoporosis
• Paget's disease of bone
• Bone metastases in cancer

• The Beta-2-Crosslaps CTx-1 plasma test is typically ordered by a healthcare provider to help diagnose and monitor bone loss, particularly in postmenopausal women or men at risk of osteoporosis.
• The test is also used to monitor the effectiveness of treatment for osteoporosis or other conditions that cause bone loss.

The Beta-2-Crosslaps CTx-1 plasma test is a blood test that measures the level of Beta-2-Crosslaps CTx-1 marker in the blood.

This test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in a vacutainer.

If the results of the Beta-2-Crosslaps CTx-1 plasma test are abnormal, it may indicate an increased rate of bone resorption, which can be associated with a range of conditions, such as osteoporosis, Paget's disease of bone, and bone metastases in cancer.

If the levels of B-2-C CTx-1 in your blood decrease with treatment, it may indicate that bone resorption is slowing down and that the treatment is working.

There are typically no special preparations required before the Beta-2-Crosslaps CTx-1 test. However, it's always a good idea to check with your healthcare provider to confirm if there are any specific instructions or recommendations for your individual case.

The Beta-2-Crosslaps CTx-1 test is typically recommended for individuals who are at risk of developing osteoporosis, have symptoms that may be indicative of a potential issue with bone health, as well as those who have been diagnosed with the condition. This may include:

• Postmenopausal women
• Men over the age of 70
• People with certain medical conditions or who take certain medications that can increase the risk of bone loss
• Bone pain or tenderness
• Decreased height or stooped posture
• Fractures, particularly in the hip, spine, or wrist
• A family history of osteoporosis or other conditions that affect bone health
• A personal history of medical conditions that increase the risk of bone loss

Beta-2-Crosslaps (B-2-C or β2-Crosslaps)

CTx-1 (C-terminal telopeptide of type 1 collagen)

Bone Resorption Markers

C-telopeptide test

Cross-Linked C-Telopeptide (CTX) test

β-CTX