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Comprehensive Allergy Panel
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Comprehensive Allergy Panel Details in Brief
| Also Known As | Allergy Panel - Comprehensive, Comprehensive IgE Allergy Panel, IgE Allergy Blood Test |
|---|---|
| Purpose | To help identify allergic sensitisation to a broad range of food, environmental, pollen, mould, dust mite and animal dander allergens |
| Preparation | Clinical history required |
| Fasting | Fasting not required |
| Reporting Time | Same day |
| Cost | 16,000 |
What is the Comprehensive Allergy Panel?
The Comprehensive Allergy Panel is a blood test that helps assess whether your immune system is reacting to multiple possible allergy triggers. It measures total IgE and allergen-specific IgE antibodies in your blood.
IgE is an antibody produced by your immune system. In people with allergies, IgE may react to substances such as certain foods, dust mites, moulds, pollens, pet dander or cockroach allergens. This panel helps your doctor understand which allergens may be linked to your symptoms and plan suitable treatment or avoidance advice.
The test is done using a serum sample, which is prepared from blood collected from a vein in your arm.
What Does a Comprehensive Allergy Panel Measure?
The Comprehensive Allergy Panel measures your immune response to a wide range of possible allergens:
- Total IgE level: Measures the overall amount of IgE antibody in your blood and helps support allergy screening.
- Allergen screening: Includes Phadiatop allergen screening to help identify atopic allergy patterns.
- Food allergens: Checks IgE response to common food triggers such as egg white, milk, fish, shrimp, wheat, peanut, soyabean, orange, banana, peach, apple, lentil and chickpea.
- Indoor allergens: Includes allergens such as dust mite and cockroach, which may be linked to sneezing, blocked nose, wheezing or long-term respiratory symptoms.
- Animal dander allergens: Checks sensitivity to cat, dog, horse and cow dander.
- Grass, tree and weed pollens: Includes allergens such as eucalyptus, mesquite, bermuda or dhoob grass, timothy, Johnson grass, common ragweed, mugwort, English plantain, goosefoot and prickly saltwort.
- Mould allergens: Includes moulds such as Penicillium Chrysogenum, Cladosporium Herbarum, Aspergillus Fumigatus and Alternaria Alternata.
Comprehensive Allergy Panel: Who Needs It and Why It’s Done
What Symptoms May Call for a Comprehensive Allergy Panel?
Your doctor may recommend this test if you have symptoms that suggest an allergic condition, such as:
- Frequent sneezing, runny nose or blocked nose
- Itchy, watery or red eyes
- Repeated cough, wheezing or breathing difficulty
- Skin rashes, itching, hives or eczema-like symptoms
- Swelling after exposure to certain foods or environmental triggers
- Stomach pain, nausea, vomiting or loose stools after eating specific foods
- Symptoms that worsen around dust, pets, mould, pollen or certain foods
- Recurrent allergy symptoms without a clearly known trigger
Who Should Get a Comprehensive Allergy Panel?
This test may be useful for:
- People with suspected food allergy symptoms
- People with allergic rhinitis, asthma or atopic dermatitis
- People with repeated respiratory or skin allergy symptoms
- Children or adults with multiple suspected allergy triggers
- People who need help identifying possible environmental or food allergens
- People being evaluated before allergy management or allergen avoidance planning
- People whose doctor wants to assess allergic sensitisation using a blood test
Why is a Comprehensive Allergy Panel Done?
The Comprehensive Allergy Panel is done to help identify possible allergy triggers by measuring IgE antibodies against multiple allergens. It supports your doctor in connecting your symptoms with likely food, indoor, outdoor or environmental allergens.
A positive result shows sensitisation to an allergen, but it does not always confirm that the allergen is causing your symptoms. Your doctor will interpret the report along with your clinical history.
Importance of Comprehensive Allergy Panel
A Comprehensive Allergy Panel is important because allergic symptoms can overlap with many other conditions. This test helps narrow down possible triggers across food, dust mite, mould, pollen, cockroach and animal dander categories.
The results can help your doctor guide dietary changes, environmental control measures, allergy medicines, further allergen-specific testing or treatment planning. It may also help reduce repeated exposure to allergens that could worsen asthma, allergic rhinitis, eczema or other allergic conditions.
Comprehensive Allergy Panel Booking & Reports - Metropolis Healthcare
How to Book the Comprehensive Allergy Panel and Get Your Reports?
- Simple Online Booking
Booking can be done through the Metropolis Healthcare App or website. Select the Comprehensive Allergy Panel, choose a convenient time slot, and provide your address for a blood test at home. You can also visit the nearest Metropolis Lab if you prefer to give the sample directly at the lab. - Safe Home Sample Collection
Our trained phlebotomists ensure timely collection of your sample while strictly following all safety and hygiene protocols. - Sample Tracking Updates
Stay informed at every step. From collection to testing, you can track your sample directly through the Metropolis Healthcare website. - Accurate Laboratory Testing
Your sample is processed at NABL and CAP accredited laboratories using ImmunoCAP technology for allergy testing. - Quick and Easy Reports
Receive your test reports promptly via email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app.
Is Home Sample Collection for Comprehensive Allergy Panel Available Near You?
Yes, Metropolis Healthcare offers home sample collection for Comprehensive Allergy Panel. This service saves you time, reduces the need for travel, and ensures professional sample handling while maintaining strict quality standards.
In how much time will I get Comprehensive Allergy Panel report?
Reports are usually available on the same day once the sample reaches the lab.
Note: Reporting time may vary based on your location.
Where can I see or get Comprehensive Allergy Panel results?
Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis Healthcare website using your credentials or use the Metropolis Healthcare App to view and download your reports. Additionally, test reports are sent via email or WhatsApp and you also have the option to collect a physical copy directly from the lab.
Interpreting Comprehensive Allergy Panel Results
What Your Comprehensive Allergy Panel Results May Indicate
Your Comprehensive Allergy Panel results show whether your blood has raised IgE levels or allergen specific IgE antibodies against the tested allergens. A positive result suggests allergic sensitisation, but your doctor will interpret it along with your symptoms, medical history and exposure to specific triggers.
|
Parameter or Test Component |
Reference Range or Result Pattern |
What a Raised or Positive Result May Indicate |
What a Negative or Lower Result May Indicate |
|
IgE Total antibody |
0 to 100 IU/mL |
Raised total IgE may be seen in asthma, allergic bronchopulmonary aspergillosis, primary immunodeficiency, parasitic infections, inflammatory diseases and some cancers |
Low IgE levels may be seen in some auto immune disorders. A normal or low value does not always rule out allergy |
|
Phadiatop Allergen Screening |
Negative: < 0.35 PAU/L, Positive: >= 0.35 PAU/L |
A positive result suggests atopic allergy and may need more specific allergen testing to identify the responsible trigger |
A negative result suggests that symptoms may not be due to the common allergens included in the screening mix |
|
Specific Allergen IgE |
Negative: < 0.1 kUA/L, Positive: >= 0.1 kUA/L |
A positive result suggests sensitisation to that specific allergen. Clinical relevance depends on your symptoms and exposure history |
A negative result suggests sensitisation to that specific allergen is less likely |
How Should You Prepare for a Comprehensive Allergy Panel?
The Comprehensive Allergy Panel requires simple preparation. Follow these points before your test:
- Fasting not required: You can eat and drink normally before the test unless your doctor has advised fasting for another test.
- Clinical history required: Share your symptoms, suspected triggers, existing allergies, asthma history, eczema history and food reactions with your doctor.
- Inform your doctor about medicines: Tell your doctor about all medicines and supplements you take, especially if you are on long-term allergy, asthma or immune-related treatment.
- Biotin caution: If you take high-dose biotin supplements of more than 5 mg per day, keep at least an 8-hour gap before blood collection, as biotin may interfere with some immunoassays.
- Normal hydration: Drink water as you usually do before the blood test.
- Avoid self-restriction: Do not remove major foods from your diet only because you suspect an allergy. Follow your doctor’s advice before making dietary changes.
How Is a Comprehensive Allergy Panel Done? (Step-by-Step Procedure)
The Comprehensive Allergy Panel is performed using a simple blood collection process:
- Preparation: A tourniquet is tied around your upper arm to make the vein more visible.
- Cleaning: The puncture site is cleaned with an antiseptic solution.
- Sample Collection: A sterile needle is used to draw about 3 ml of blood into a gel vacutainer.
- Completion: The needle is removed, and a bandage is applied to the site.
- Processing: The blood sample is processed to obtain serum and tested using the ImmunoCAP method to measure total IgE and allergen-specific IgE responses.
Conditions That May Affect Comprehensive Allergy Panel Accuracy
Certain patient-related factors can influence how your Comprehensive Allergy Panel results are interpreted:
- High-dose biotin use: Biotin supplements above 5 mg per day may interfere with some immunoassays. Keep at least an 8-hour gap before sample collection if you take high-dose biotin.
- Recent allergic flare: Active symptoms after recent exposure to an allergen may affect how strongly the result matches your clinical condition.
- Parasitic infections: Some parasitic infections can raise total IgE levels and may affect interpretation.
- Immune system disorders: Primary immunodeficiency, autoimmune conditions or other immune-related diseases may influence IgE levels.
- Inflammatory conditions: Ongoing inflammatory illnesses may be linked with raised total IgE in some cases.
- Clinical history mismatch: A positive IgE result shows sensitisation, but it may not confirm allergy unless your symptoms match the suspected allergen exposure.
Diseases That A Comprehensive Allergy Panel Can Help Detect
The Comprehensive Allergy Panel can help your doctor evaluate several allergy-related conditions:
- Allergic rhinitis: Helps identify inhalant allergens that may trigger sneezing, runny nose, blocked nose or itchy eyes.
- Allergic asthma: Helps assess whether allergens such as dust mite, mould, pollen, cockroach or animal dander may be linked to asthma symptoms.
- Atopic dermatitis: Supports evaluation of allergic sensitisation in people with eczema-like skin symptoms.
- Food allergy: Helps detect IgE sensitisation to foods such as egg, milk, fish, shrimp, wheat, peanut, soyabean, lentil, chickpea and selected fruits.
- Mould allergy: Helps identify sensitisation to mould allergens that may worsen respiratory or skin symptoms.
- Pet dander allergy: Helps assess sensitivity to animal dander such as cat, dog, horse or cow dander.
- Pollen allergy: Helps detect sensitisation to selected grass, tree and weed pollens.
- Allergic bronchopulmonary aspergillosis: Raised total IgE and Aspergillus-related sensitisation may support further evaluation when clinically suspected.
References
- Ansotegui IJ, Melioli G, Canonica GW, Caraballo L, Villa E, Ebisawa M, et al. IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper. World Allergy Organ J. 2020;13(2):100080. PMID:32128023.
- Santos AF, Riggioni C, Agache I, Akdis CA, Akdis M, Alvarez-Perea A, et al. EAACI guidelines on the diagnosis of IgE-mediated food allergy. Allergy. 2023;78(12):3057-3076. PMID:37815205.
- Kerkhof M, Dubois AE, Postma DS, Schouten JP, de Monchy JG. Role and interpretation of total serum IgE measurements in the diagnosis of allergic airway disease in adults. Allergy. 2003;58(9):905-911. PMID:12911420.
- Hamilton RG, Mudd K, White MA, Wood RA. Extension of food allergen specific IgE ranges from the ImmunoCAP to the IMMULITE systems. Ann Allergy Asthma Immunol. 2011;107(2):139-144. PMID:21802022.
Comprehensive Allergy Panel Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Comprehensive Allergy Panel with a clear pricing structure.
The Comprehensive Allergy Panel Price in Mumbai is ₹ 16,000 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
The Comprehensive Allergy Panel can be done at any suitable time of the day. Follow the appointment time given during booking and inform your doctor about your allergy symptoms and suspected triggers.
No, overnight fasting is not mandatory. You can eat and drink normally before the test unless your doctor has advised fasting for another test being done at the same time.
Mild dehydration is unlikely to significantly change IgE results, but normal hydration helps make blood collection easier. Drink water as you usually do before the test.
No special diet is required. Do not stop medicines or remove foods from your diet unless your doctor advises it. Inform your doctor about all medicines, supplements and any high-dose biotin use.
A healthcare professional cleans the puncture site, inserts a sterile needle into a vein in your arm and collects about 3 ml of blood in a gel vacutainer. The process usually takes only a few minutes.
The risks are minimal and similar to a routine blood test. You may feel slight pain, bruising or mild dizziness during or after sample collection. Serious complications are rare.
Total IgE has a biological reference interval of 0-100 IU/mL. For allergen-specific IgE, values below 0.1 kUA/L are usually considered negative, while values at or above 0.1 kUA/L are considered positive for sensitisation.
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