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Total Proteins Test - Serum

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Total Protein Test Overview

As part of a general health check-up, to ascertain your nutritional status or to screen for and help find out certain liver and kidney disorders as well as other diseases.

Proteins are the building blocks of the body and most essential for healthy growth and development of the body. Any abnormality in total proteins could mean underlying conditions.

Proteins are important components that are required for the growth and development of the body. Protein serum test measures the levels of total proteins [albumin and globulin] as well as their individual levels in the blood. 

WRITTEN BY: Dr.Shibani R Medical Writer, Medical Affairs

Reasons for Undergoing the Total Protein Test

The total protein test, commonly referred to as the TP test, is an essential diagnostic tool that provides valuable insights into various health conditions. This test measures the total amount of proteins in the blood, which are critical for numerous bodily functions. Here are some key reasons for undergoing the total protein blood test:

  • Diagnosing Liver and Kidney Diseases: The TP test helps assess the function of the liver and kidneys by measuring the proteins produced by these organs. Abnormal protein levels can indicate underlying health issues.
  • Identifying Nutritional Disorders: The total protein test is instrumental in detecting nutritional disorders such as malnutrition and malabsorption syndromes. Low protein levels may signal insufficient dietary intake or absorption issues.
  • Detecting Certain Types of Cancer: This test can help identify specific cancers, such as multiple myeloma, characterised by abnormal protein accumulation in the blood.
  • Assessing Chronic Infections and Inflammatory Conditions: The total protein test is also used to monitor chronic infections and inflammatory conditions, including HIV and viral hepatitis, by evaluating protein levels related to immune response.
  • Routine Health Checkups: For individuals with risk factors for liver or kidney diseases, routine total protein blood tests are vital for early detection and management.
  • Monitoring Existing Conditions: The total protein test is crucial for tracking the health of individuals diagnosed with liver or kidney diseases or those on medications that may impact these organs. Regular monitoring ensures timely intervention and effective management of health conditions.

List of Parameters Considered During the Total Protein Test

The total protein blood test measures two main types of proteins in the blood: albumin and globulins. Here's a brief explanation of each parameter:

  • Albumin: Produced by the liver, it helps prevent fluid leakage from blood vessels and carries essential substances throughout the body. Low levels may indicate liver, kidney, or thyroid disease, while high levels are less common but can occur in severe dehydration.
  • Globulins: Crucial for the immune system, they help fight infections and are produced by the liver and immune system. Low levels may suggest liver, kidney, or immune disorders, while high levels can indicate chronic inflammation, infection, or certain cancers.
  • Albumin/Globulin (A/G) Ratio: Compares albumin to globulin levels in the blood. An abnormal ratio may indicate autoimmune diseases, multiple myeloma, cirrhosis, kidney disease, genetic deficiencies, or leukaemia.

Home Collection for Total Protein Test Near You

Choosing Metropolis Healthcare's home sample collection service for your total protein test provides numerous advantages. A trained phlebotomist will visit your home to collect blood samples, ensuring both comfort and safety.

Metropolis Healthcare maintains high standards in sample handling, ensuring accurate test result. You can expect timely and reliable results, Metropolis Healthcare is committed to making healthcare accessible and providing quality diagnostic solutions conveniently at home.

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Total Proteins Test - Serum Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Total Proteins Test - Serum with a clear pricing structure.

The Total Proteins Test - Serum Price in Mumbai is ₹ 300 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

Unexplained weight loss, excess fatigue, swelling, or oedema caused by extra fluid in tissues and any symptoms that indicate liver or kidney disorder indicates a protein disorder. Eating more protein or a protein rich diet will have no bearing on the total proteins in your blood. A healthy nutritious diet is important to maintain optimal protein levels. Certain medications like steroid may affect the total protein level and it will be important to stop medication before undertaking the test.

Total proteins test is ordered if the doctor suspects malnutrition, malabsorption or a liver or kidney disorder. The total proteins test and the A/G ratio is also part of a routine check-up.

The important building blocks of all cells and tissues are proteins; they are important for body development and health. They make the structural part of most organs and form enzymes and hormones that regulate body functions. Albumin and Globulin are the two major proteins. Albumin makes up 60% of the total protein and is produced by the liver. They basically nourish tissues and transport hormones, vitamins and drugs all through the body. Globulin on the other hand helps fight infection. Some of the globulin is produced by the immune system. They include enzymes, hormones, carrier proteins, and numerous other types of proteins.

This test is done to know:
-Patient's nutritional status
-In suspected cases of liver disease
- In renal diseases 
- In GI disease.

The test measures the levels of total proteins, albumin, globulin, Albumin/Globulin Ratio in the blood. 

This test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer. 

Total Proteins: High levels may occur due to infections or inflammations, certain blood disorders or even physiological causes [pregnancy, age]. 
Low levels may occur due to malnutrition, liver or kidney disorders, burns , post-surgeries etc. 
Albumin : High levels may occur due to dehydration which may be due to diarrhoea or other conditions.
 Low albumin levels may occur due to certain medications or post surgeries. 
Globulin: High levels may occur due to infections, inflammations, immune disorders or even malignancies.
Low levels may occur due to kidney or liver disorders and malnutrition.
A/G ratio: High ratio may occur due to genetic conditions and certain malignancies.
Low levels may occur due to autoimmune disorders, kidney or liver diseases.   

The total protein test measures the combined levels of albumin and globulins in the blood, helping diagnose and monitor conditions like liver and kidney diseases, nutritional problems, infections, and certain cancers.

Common symptoms that may lead to a total protein blood test include swelling in the feet, ankles, legs, or abdomen, fatigue, unexplained weight loss, loss of appetite, nausea, vomiting, jaundice, and blood in the urine.

The total protein test, or total protein blood test, measures the levels of albumin and globulins in the blood, providing valuable insights into a person’s overall health. High or low levels of these proteins can indicate various health issues. For instance, low albumin levels may suggest liver or kidney diseases, while elevated globulin levels could point to chronic infections or inflammatory conditions.

Additionally, the total protein test is instrumental in detecting nutritional disorders such as malnutrition and malabsorption syndromes, where the body cannot absorb nutrients. It can also help identify specific types of cancer, including multiple myeloma, characterized by abnormal protein levels. By assessing these protein levels, healthcare providers can gain essential information for diagnosing and monitoring a range of medical conditions, ensuring appropriate treatment plans are established.

The total protein test reports provide crucial information about the levels of proteins in the blood, specifically albumin and globulins, along with the albumin-to-globulin (A/G) ratio. These reports indicate whether the total protein levels and the A/G ratio fall within normal ranges. Normal values typically suggest that the liver and kidneys are functioning properly and that the individual has adequate nutritional status. Conversely, abnormal results can be indicative of several health issues. For instance, low total protein levels may suggest liver or kidney diseases, where protein synthesis or retention is impaired. Low albumin levels could signal malnutrition or malabsorption syndromes. Elevated globulin levels may indicate chronic infections or inflammatory conditions. Additionally, abnormal results might raise suspicion for certain cancers, prompting further investigation and testing. Therefore, the total protein test reports are essential for diagnosing and monitoring various medical conditions effectively.

If the total protein test reports are positive, indicating elevated total protein levels, it typically suggests an underlying condition that needs further evaluation. High total protein levels can be associated with several health issues, including chronic inflammation, infections, liver disease, or certain types of cancer, such as multiple myeloma. In response to a positive total protein test result, healthcare providers will often recommend additional diagnostic tests to pinpoint the specific cause.

The benefits of a total protein test include early detection and diagnosis of liver and kidney diseases, nutritional problems, infections, and certain cancers, as well as monitoring the health of individuals with existing conditions and assessing treatment effectiveness.

No special preparations, including fasting, are generally required for a total protein test. However, a healthcare provider may advise you to avoid certain medications or foods that could affect the results.

The normal range for total protein is typically between 6.0 and 8.3 grams per decilitre (g/dL) or 60 to 83 g/L, although normal values may vary slightly among different laboratories.

Increasing total protein levels involves addressing the underlying cause, which may include improving nutrition, treating underlying diseases, and ensuring proper nutrient absorption. Consult a healthcare provider for personalised advice.

High total protein levels can indicate dehydration, chronic inflammation, infections like HIV or viral hepatitis, certain cancers like multiple myeloma, or pregnancy.

The total protein test results are typically available within 4 hours, although this may vary depending on the healthcare provider and the time/day when the sample is collected and processed.

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