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TORCH-5 IgM Profile Test

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TORCH IgM Test Overview

TORCH is an acronym from five potential infectious agents that can be transmitted from mother to foetus through the placenta. These viruses can cause serious congenital malformations especially when mother acquires the infection for the first time during the first trimester.
The full form of TORCH is toxoplasmosis, rubella, cytomegalovirus (CMV), herpes simplex (HSV).

A class of viral infections can affect pregnant women. These prenatal infections could lead to infants with birth abnormalities. When a baby exhibits any symptoms suggestive of such infections, such as mental disabilities, deafness, heart problems, cataracts, or jaundice, or if you have been subjected to certain communicable diseases or just become ill while pregnant, this test is required. The avoidance of problems in newborns is aided by early detection and treatment.

What is the TORCH-5 IgM test?

The Torch 5 Antibodies IgM ELISA Blood Test is intended to identify IgM antibodies in the blood against five infections in the panel that may affect pregnant women (perinatal infections). The abbreviation TORCH stands for the five possible infectious agents, Toxoplasma, Other (HIV, hepatitis virus, varicella-zoster virus, parvovirus), rubella, cytomegalovirus (CMV), and herpes simplex virus (HSV), that might spread from the mother to the fetus via the placenta. These viruses have the potential to result in severe birth defects, particularly when the mother contracts the illness for the first time during the initial trimester.

Who Should Do the TORCH-5 IgM Test?

Pregnant women are subjected to this test to look for any of the five suggestive illnesses on the panel. Birth abnormalities in neonates may be avoided by early detection and management of such prenatal infections. This test is carried out during a woman's initial prenatal appointment as part of a regular examination. Additionally, this test is advised for newborns who exhibit any symptoms or telltale indicators of the infections on the panel.

What Other Tests Are Ordered Along with the TORCH-5 IgM Test?

  1. TORCH IgG - When a person has previously had an infection or is dealing with an infection with or without the development of symptoms, IgG antibodies against the viral pathogen will be present. This test is thus done to confirm exposure to the pathogen.
  2. IgG avidity testing - A helpful serological test for toxoplasmosis is the IgG avidity test, which in many instances can confirm or rule out the disease's active form.
  3. Amniocentesis or chorionic villus sampling - Two prenatal diagnostic procedures are chorionic villus sampling and amniocentesis. Genetic abnormalities can be detected with either of the two tests.

Written by: Dr R.Lakshmi Priya, M.B.B.S, MD, Dept. of Microbiology and Molecular Biology 

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TORCH-5 IgM Profile Test Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the TORCH-5 IgM Profile Test with a clear pricing structure.

The TORCH-5 IgM Profile Test Price in Mumbai is ₹ 1,820 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

TORCH IgM panel is indicated for pregnancy where congenital foetal infection is suspected i.e., IUGR, foetal hydrops, USG changes. Patients with significant contact with patients suffering from rubella should also be investigated.
If during pregnancy it is proven that there has been exposure of foetus to these infection that doctor will advise treatment and comment on health of foetus.

If it is established that the fetus was exposed to certain infections while the mother was pregnant, the doctor may recommend this test to decide on treatment based on his observations of the health of the fetus

TORCH IgM test measures IgM antibodies against Toxoplasma, CMV, Rubella, HSV 1 & 2

The blood sample is taken from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a  little sting when the needle goes in or out. This usually takes less than five minutes.You may feel slight tenderness in the area that usually subsides in some time. Make sure you are dressed in a short-sleeved shirt or one with easily-rollable sleeves.

TORCH IgM positive - This may indicate a recent infection. However, IgM antibodies can be false positive and also the levels of the antibodies may remain elevated till 6 months post cure.
It is important to time when the infection was acquired by the mother; this can be done through IgG avidity testing.
If it is suggested that infection occurred during the pregnancy then doctor may advise an invasive test like amniocentesis of chorionic villus sampling.
TORCH IgM negative - This means there is no evidence of exposure to the said viruses in near past or the antibodies are yet to develop

This test is administered to expectant mothers to detect any of the five suggested illnesses on the panel. This test is also recommended for infants and newborns who show any signs or symptoms of the infections listed on the panel.

During a woman's initial prenatal appointment, this test is carried out as part of a regular examination.

Before going for the Torch-5 IgM test, let your doctor know if you are taking any drugs and have any allergies or underlying medical conditions. Normal eating and drinking are permitted. However, your doctor could insist that you abstain from food and drink for a certain period before the test. You will receive detailed instructions from your doctor.

  • IgM and IgG negative, no sensitivity to infection.
  • IgM and IgG + for acute infection.
  • IgM negative and IgG positive for prior infection.

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