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Thyroglobulin Test

Also known as: Thyroglobulin

50+ booked in last 3 days

Thyroglobulin Details in Brief

Also Known As Tg Test, Thyroid Cancer Marker Test
Purpose To monitor thyroid cancer treatment and detect recurrence after thyroid surgery or radioactive iodine therapy
Preparation Avoid high-dose biotin supplements (more than 5 mg/day) for at least 8 hours before blood collection
Fasting Fasting not required
Reporting Time After 8 hours
Cost 1,800

What is a Thyroglobulin Test?

The Thyroglobulin test is a blood test that measures the amount of thyroglobulin, a protein made by your thyroid gland. It is mainly used to monitor patients after thyroid cancer treatment, such as surgery or radioactive iodine therapy. Once your thyroid gland is removed or destroyed during treatment, thyroglobulin levels should drop to nearly zero. If the test shows increasing levels later, it may indicate that some thyroid tissue or cancer cells remain.

This test requires a small blood sample drawn from a vein in your arm.

What Does a Thyroglobulin Test Measure?

The thyroglobulin blood test provides valuable information about your thyroid health and cancer treatment progress:

  • Cancer Treatment Monitoring: Checks how well thyroid cancer treatment has worked after surgery or radioactive iodine therapy.
  • Cancer Recurrence Detection: Detects any return of thyroid cancer by identifying rising thyroglobulin levels.
  • Therapy Effectiveness Assessment: Evaluates whether thyroid tissue has been completely removed.
  • Post-Therapy Monitoring: Helps guide follow-up care after thyroidectomy or radioiodine treatment.
  • Differentiation of Conditions: Distinguishes between residual thyroid tissue and new tumour growth.

Thyroglobulin Test: Who Needs It and Why It’s Done

What Symptoms May Call for a Thyroglobulin Test?

This test is usually done for monitoring rather than symptoms, but your doctor may order it if you experience:

  • Neck swelling or a lump after thyroid surgery
  • Persistent hoarseness or difficulty swallowing
  • Unexplained fatigue after thyroid treatment
  • Signs suggesting thyroid cancer recurrence

Who Should Get a Thyroglobulin Test?

This test is especially important for:

  • Patients treated for papillary or follicular thyroid cancer
  • Individuals who have undergone thyroidectomy or radioactive iodine ablation
  • People being monitored for possible thyroid cancer recurrence
  • Patients receiving long-term follow-up care after thyroid cancer treatment

Why is a Thyroglobulin Test Done?

The test is done to ensure thyroid cancer treatment has been successful and to detect any signs of recurrence early, allowing timely medical intervention.

Importance of a Thyroglobulin Test

Monitoring thyroglobulin levels helps track whether thyroid cancer treatment was effective and ensures early detection of recurrence. This test is not used to diagnose thyroid cancer initially but is a crucial tumour marker for ongoing follow-up after treatment. Stable or low levels mean successful therapy, while rising levels may need further investigation.

Thyroglobulin Test Booking & Reports – Metropolis Healthcare

How to Book the Thyroglobulin Test and Get Your Reports?

  1. Simple Online Booking
    Book the Thyroglobulin Test easily through the Metropolis Healthcare App or website. Choose your preferred time slot and select home sample collection or visit your nearest Metropolis Lab.
  2. Safe Home Sample Collection
    Our expert phlebotomists collect your sample safely and comfortably at home, following strict hygiene and safety standards.
  3. Sample Tracking Updates
    You can track your sample’s status in real time through the Metropolis Healthcare website.
  4. Accurate Laboratory Testing
    Your sample is analysed in our NABL & CAP accredited laboratories using advanced ECLIA technology for high-precision results.
  5. Quick & Easy Reports
    Access your results conveniently through email, WhatsApp, or the Metropolis Healthcare website and app.

Is Home Sample Collection for Thyroglobulin Test Available Near You?

Yes, Metropolis Healthcare offers home collection for the Thyroglobulin Test. A trained phlebotomist visits your home at your preferred time, ensuring a comfortable, safe, and hassle-free sample collection experience.

In How Much Time Will I Get the Thyroglobulin Test Report?

Reports are usually available within 8 hours once the sample reaches the laboratory.
Note: Reporting time may vary depending on your location.

Where Can I See or Get Thyroglobulin Test Results?

You can view and download your test results from the Metropolis Healthcare website or app. You’ll also receive your reports via email or WhatsApp. A printed copy can be collected from your nearest Metropolis Lab.

Interpreting Thyroglobulin Test Results

What Your Thyroglobulin Test Results May Indicate

Parameter

Normal Range

High Values May Indicate

Low Values May Indicate

Thyroglobulin

1.6–60 ng/mL

Possible thyroid cancer recurrence, metastasis, or remaining thyroid tissue

Effective thyroidectomy or complete cancer removal

 

How Should You Prepare for a Thyroglobulin Test?

Proper preparation ensures accurate results:

  • Fasting not required: You can eat and drink normally before the test.
  • Avoid biotin supplements: Stop taking high-dose biotin (more than 5 mg/day) at least 8 hours before sample collection.
  • Provide clinical history: Inform your doctor about your previous thyroid surgery, cancer treatment, or radioactive iodine therapy.
  • Medication review: Tell your doctor about all medications or supplements you are taking.
  • Stay relaxed: Get adequate rest before the test to avoid stress-related hormonal fluctuations.

How Is a Thyroglobulin Test Done? (Step-by-Step Procedure)

The Thyroglobulin test is a simple blood collection process:

  • Preparation: An elastic band is placed around your upper arm to make the veins more visible.
  • Cleaning: The area is cleaned with an antiseptic solution.
  • Sample Collection: A sterile needle is inserted into your vein to collect about 3 ml of blood in a gel vacutainer.
  • Completion: The needle is removed and a small bandage is applied to the puncture site.
  • Processing: The sample is analysed using Electrochemiluminescence Immunoassay (ECLIA) technology to measure thyroglobulin levels.

Conditions That May Affect Thyroglobulin Test Accuracy

Certain factors can influence your Thyroglobulin test results:

  • High-dose biotin intake: Biotin supplements above 5 mg/day can interfere with test accuracy.
  • Recent thyroid procedures: Blood drawn too soon after surgery, biopsy, or radioactive therapy can show temporarily elevated results.
  • Pregnancy and newborn status: Thyroglobulin levels are naturally higher in pregnant women and newborns.
  • Autoantibodies: The presence of anti-thyroglobulin antibodies can interfere with the measurement.
  • Severe illness or stress: May cause minor fluctuations in hormone-related proteins.

Diseases That a Thyroglobulin Test Can Help Detect

The Thyroglobulin test helps identify or monitor:

  • Papillary thyroid carcinoma
  • Follicular thyroid carcinoma
  • Metastatic thyroid cancer
  • Hyperthyroidism (excluding factitious hyperthyroidism)
  • Recurrence of thyroid cancer after surgery or radioactive iodine therapy

Thyroglobulin Test Price in Different Cities

The cost of a Thyroglobulin Test may vary depending on your location. Here's a table showing the approximate price range for the Thyroglobulin Test at Metropolis Healthcare in major Indian cities:

City

Approximate Cost (INR)

Mumbai

₹ 1800 to ₹ 1950

Delhi

₹ 1800 to ₹ 1950

Bengaluru

₹ 1800 to ₹ 1950

Chennai

₹ 1800 to ₹ 1950

The Thyroglobulin Test cost may vary depending on the city and the specific tests included in the panel. However, Metropolis Healthcare offers competitive Thyroglobulin Test prices across major cities in India.

 

References

  1. Pacini, F., et al. (2003). Thyroglobulin determination in thyroid cancer: Clinical use and limitations. Endocrine Reviews, 24(2), 191–232. PMID: 12700178
  2. Spencer, C.A., et al. (2014). Challenges in the measurement of thyroglobulin. Clinical Endocrinology, 81(1), 18–25. PMID: 24410884
  3. Mazzaferri, E.L., & Kloos, R.T. (2001). Current approaches to thyroid cancer follow-up. Journal of Clinical Endocrinology & Metabolism, 86(4), 1447–1463. PMID: 11297567
  4. Giovanella, L., et al. (2011). Serum thyroglobulin measurement using highly sensitive assays. Thyroid, 21(4), 451–456. PMID: 21473793
  5. Haugen, B.R., et al. (2016). 2015 American Thyroid Association guidelines for management of thyroid nodules and differentiated thyroid cancer. Thyroid, 26(1), 1–133. PMID: 26462967
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Thyroglobulin Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Thyroglobulin with a clear pricing structure.

The Thyroglobulin Price in Mumbai is ₹ 1,800 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

It measures the level of thyroglobulin protein in your blood to monitor thyroid cancer treatment and detect recurrence.

Fasting not required; you can eat and drink normally before the test.

It is done after thyroid surgery or radioactive iodine therapy to monitor treatment success and recurrence.

Yes, high-dose biotin supplements can interfere. Avoid them at least 8 hours before testing.

High levels may indicate remaining thyroid tissue, cancer recurrence, or metastasis.

Low or undetectable levels suggest effective thyroid cancer treatment and no residual tissue.

Yes, but inform your doctor about all medications or supplements you’re taking.

Your doctor will decide the frequency, often every 6–12 months after thyroid cancer treatment.<

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We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

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