Thrombin Time (TT)

Thrombin time measures how long it takes for your blood to clot using the protein thrombin. Thrombin is crucial in the blood-clotting process, converting fibrinogen into fibrin to create a stable clot. This test evaluates the efficiency of this vital clotting factor.

• To diagnose and monitor blood clotting disorders.
• To assess bleeding tendencies and the risk of excessive bleeding.
• To evaluate liver function and monitor heparin therapy effectiveness.
• To investigate unexplained bruising or prolonged bleeding post-surgery.

A doctor will recommend this test:

• If you have unexplained bleeding issues, such as prolonged nosebleeds or heavy periods.
• Before surgery to assess clotting ability.
• On heparin therapy, to monitor dosage effectiveness.
• For those with suspected liver disease or clotting disorders.

Abnormal results may suggest liver disease, disseminated intravascular coagulation, or deficiency in clotting factors like fibrinogen or dysfibrinogenemia. Abnormalities could also indicate a risk of excessive bleeding or thrombosis. Consult your doctor for further evaluation.

During this test:

• A small blood sample will be taken from your vein.
• The sample will be tested in the lab to measure clotting time using thrombin.
• The procedure is quick and relatively painless.

Before the test:

• No fasting is required.
• Inform your doctor about any medications you are taking.
• Wear loose clothing for easy access to your arm for blood collection.
• Follow any specific instructions given by your healthcare provider.

Other tests that may be ordered alongside Thrombin Time include:

• Prothrombin Time (PT): Evaluates other aspects of blood clotting.
• Activated Partial Thromboplastin Time (aPTT): Assesses the intrinsic clotting pathway.
• Fibrinogen Test: Measures levels of fibrinogen in the blood, necessary for clot formation.

TT test or Thrombin Clot time

Haemophilia is an inherited genetic disorder that impairs proper blood clotting, leading to excessive bleeding and bruising even with minor injuries. The condition arises due to deficiencies in clotting factors VIII or IX in the blood.