Multiple Sclerosis Profile, Maxi Test

For comprehensive Diagnosis of multiple sclerosis; especially useful in patients with equivocal clinical presentation and radiological findings.

If your physician suspects inflammation in your central nervous system, they will order a CSF oligoclonal banding. If there is a presence of oligoclonal bands of protein, multiple sclerosis is sometimes suspected as the cause.

The diagnosis of multiple sclerosis (MS) is dependent on clinical, radiological, and laboratory findings. The detection of increased intrathecal immunoglobulin (Ig) synthesis is the basis for current diagnostic laboratory tests for MS. These tests include the cerebrospinal fluid (CSF) IgG index and CSF oligoclonal band (OCB) detection. Abnormal CSF IgG indexes and OCB patterns have been reported in 70% to 80% of MS patients. They are Associated withIncreased levels of disease activity and disability, conversion from a clinically isolated syndrome to early relapsing-remitting MS ,Greater brain atrophy , and increased cortical lesion load/intrathecal inflammation.CSF IgG alone Best marker of disease activity in MS patients. Increased MAG antibodies :Predicts Progression to MS , relapsing remitting multiple sclerosis (RRMS).