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Multiple Sclerosis Profile Maxi

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Overview

The diagnosis of multiple sclerosis (MS) is dependent on clinical, radiological, and laboratory findings.

A condition called multiple sclerosis (MS) has the potential to harm the brain and spinal cord (central nervous system). In MS, the immune system attacks myelin. It is the sheath that shields nerve fibres. This causes impaired brain-to-body communication. Eventually, the disease may cause irreparable damage to nerve fibres or their degeneration.

The location and degree of nerve impairment in the central nervous system affect the symptoms and signs of MS. These vary greatly from patient to patient. Some MS sufferers may become completely or partially unable to walk on their own. In accordance with the type of MS they have, other people might go for extended stretches of time without developing any new symptoms.

Multiple Sclerosis has no known treatment. Treatments exist, nevertheless, to slow the onset of attacks, alter the condition of the patient, and control symptoms.

Visual, motor and sensory impairments are hallmarks of the chronic inflammatory demyelinating illness. This is known as multiple sclerosis (MS). The results of clinical, radiographic, and laboratory tests are used to make the diagnosis of MS. Current MS diagnostic laboratory techniques are based on the detection of elevated intrathecal immunoglobulin (Ig) production.

Who should do the Multiple Sclerosis Profile Maxi test?

You should see a doctor if you display any of the following symptoms -

  • Usually affects one of the body's sides. There could be numbness or fatigue in one or more limbs.
  • Certain neck movements, especially forward bending, might cause tingling electric-shock feelings (Lhermitte sign).
  • Ineffective coordination.
  • Inability to walk or an unsteady stride.
  • Partial or total blindness in one of the eyes at a time.
  • Vertigo.
  • Issues with bowel, bladder, and sexual function.
  • Fatigue.
  • Unsteady speech.
  • Cognitive difficulties.
  • Disturbances in the mood.

Written by: Dr Vishal Wadhwa, M.D, D.N.B Microbiology, Medical Affairs

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Multiple Sclerosis Profile Maxi Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Multiple Sclerosis Profile Maxi with a clear pricing structure.

The Multiple Sclerosis Profile Maxi Price in Mumbai is ₹ 10,070 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

For comprehensive Diagnosis of multiple sclerosis; especially useful in patients with equivocal clinical presentation and radiological findings.

It can be challenging to diagnose MS. It cannot be diagnosed by a single test. Instead, to rule out some other disorders with comparable symptoms, a diagnosis often necessitates a number of tests.

If your doctor suspects you may have MS after performing a physical examination, they will probably prescribe a number of various tests.

If your physician suspects inflammation in your central nervous system, they will order a CSF oligoclonal banding. If there is a presence of oligoclonal bands of protein, multiple sclerosis is sometimes suspected as the cause.

This test assesses CSF Albumin, Serum Albumin, CSF Immunoglobulin G, Serum Immunoglobulin G, Oligoclonal Band, CSF Index and MAG Antibody.

The diagnosis of multiple sclerosis (MS) is dependent on clinical, radiological, and laboratory findings. The detection of increased intrathecal immunoglobulin (Ig) synthesis is the basis for current diagnostic laboratory tests for MS. These tests include the cerebrospinal fluid (CSF) IgG index and CSF oligoclonal band (OCB) detection. Abnormal CSF IgG indexes and OCB patterns have been reported in 70% to 80% of MS patients. They are Associated withIncreased levels of disease activity and disability, conversion from a clinically isolated syndrome to early relapsing-remitting MS ,Greater brain atrophy , and increased cortical lesion load/intrathecal inflammation.CSF IgG alone Best marker of disease activity in MS patients. Increased MAG antibodies :Predicts Progression to MS , relapsing remitting multiple sclerosis (RRMS).

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If you experience any of the following symptoms, consult a doctor -

  • Numbness or weariness in one or more limbs. This typically impacts only one side of the body at a time.
  • Certain neck motions, particularly tilting the neck forward, may give the sensation of an electric shock (Lhermitte sign).
  • Improper coordination.
  • An incapacity to move.
  • Blindness, that is either partial or total. It is typically accompanied by pain.
  • Vertigo.
  • Gastrointestinal, urinary, and sexual function problems
  • Fatigue.
  • Speech that is shaky.
  • Cognitive challenges.

If you encounter any of the symptoms listed above for an unidentified reason, consult a doctor.

For this test, both a blood test and a CSF sample are necessary. An elastic band used as a tourniquet is tightly placed around the upper arm to get a blood sample. The patient is then asked to make a fist. This facilitates the blood filling of the veins. The skin is cleansed prior to the needle insertion. The blood sample is collected using a vacutainer. Your doctor will have to take CSF samples.

Not necessarily. But you must share your medical history with your doctor before taking any of the tests.

CSF is used to diagnose MS (oligoclonal bands). This is done by qualitatively detecting increased intrathecal IgG production. One of the MS diagnostic requirements is the presence of two or more distinct CSF oligoclonal bands.

Multiple sclerosis, inflammatory neuropathy, and motor neuron diseases are all related to the myelin-associated glycoprotein antibody (MAG) presence.

Relapsing-remitting illness is present in most MS patients. They move through phases. Here they either experience the onset of new symptoms or relapse. These often last weeks or days to develop. There may be months or even years of peaceful sickness remission following these relapses.

Along with Multiple Sclerosis Profile Maxi, your doctor may recommend -

  • Evoked potential tests.
  • MRI.
  • Spinal Tap.

Blood Tests.

CSF Albumin

Serum Albumin

CSF IgG

Serum IgG

Oligoclonal Band

CSF Index

MAG Antibody

Myelin-associated glycoprotein (MAG) Antibody

Detection of MAG antibodies is associated with demyelinating sensorimotor neuropathies associated with multiple sclerosis, inflammatory neuropathies, and motor neuron diseases.

The CSF index is the CSF IgG to CSF albumin ratio compared to the serum IgG to serum albumin ratio. The CSF index is, therefore, an indicator of the relative amount of CSF IgG compared to serum. Any increase in the index is a reflection of IgG production in the CNS. The index is independent of the activity of the demyelinating process.

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