PLA2 Receptor Antibody Qualitative, serum51+ booked in last 3 days
Idiopathic membranous nephropathy is an autoimmune disease wherein antibodies target glomeruli thus leading to progressive reduction in kidney function.
PLA2R (Phospholipase A2 Receptor) is a protein that is found on the surface of cells in the kidney, specifically in the cells of the glomeruli, which are small structures in the kidneys that filter blood. The PLA2R antibody qualitative test is a blood test that is used to detect the presence of antibodies directed against PLA2R. This test is used to help diagnose a condition called primary membranous nephropathy (PMN), which is a type of kidney disease.
In PMN, the body's immune system mistakenly produces antibodies that attack the PLA2R protein on the cells in the glomeruli. The presence of these antibodies can cause inflammation and damage to the glomeruli, leading to protein in the urine, a decrease in kidney function, and even kidney failure if not treated.
The test is qualitative, meaning that it detects the presence of the antibodies but does not give a quantitative measure of the amount of antibodies. The result of the test is usually given as positive or negative, indicating the presence or absence of the antibodies.
P8229 PLA2 Receptor Antibody Quantitative, Serum
Written by: Supriya Kulkarni, Lead-Content & Training
PLA2 Receptor Antibody Qualitative, serum Price
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The PLA2 Receptor Antibody Qualitative, serum Price in Mumbai is ₹ 4,640 .
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Frequently Asked Questions
Test is done to diagnose patients suffering from idiopathic membranous nephropathy.
This test is done to detect an autoantibody in your blood against glomeruli.
Idiopathic membranous nephropathy is an autoimmune disease wherein antibodies target glomeruli thus leading to progressive reduction in kidney function. It is both a diagnostic and a prognostic test (helps check improvement after treatment).
- PLA2 Receptor Antibody Qualitative test detects autoantibodies against phospholipase A2 receptors (PLA2R) which is useful in the diagnosis of primary membranous glomerulonephritis (PMN).
- The PLA2R (Phospholipase A2 receptor) antibody qualitative test is typically done in individuals who have signs and symptoms of kidney disease such as proteinuria, decreased kidney function, or kidney failure. This test may also be done in patients with unexplained hypertension, as primary membranous nephropathy can be a cause of hypertension.
- Additionally, the test may be done in patients with other autoimmune diseases, as primary membranous nephropathy is often associated with other autoimmune diseases.
- It is usually recommended that the test is done in patients who have persistent proteinuria, even after exclusion of other causes such as kidney stones, urinary tract infections, and other kidney diseases.
PLA2 Receptor Antibody Qualitative test qualitatively detects the presence of autoantibodies against phospholipase A2 receptors (PLA2R).
This test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer
If the PLA2R (Phospholipase A2 receptor) antibody qualitative test is positive, it may indicate the presence of primary membranous nephropathy (PMN). A positive test result suggests that the patient has antibodies directed against the PLA2R protein.
Primary membranous nephropathy (PMN) is a type of kidney disease characterized by the formation of antibodies that attack the PLA2R (Phospholipase A2 receptor) protein on the cells in the glomeruli of the kidney, leading to inflammation and damage to the glomeruli.
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