NMDA Receptor Antibody (NR1) , CSF (Undiluted) Test
₹6390
₹6390
N-methyl-D-aspartate (NMDA) receptor antibodies are associated with the different sub units of the NMDA receptor.
For differential diagnosis of Autoimmune Epilepsy, Seizure disorders, Autoimmune Encephalitis.
This test is performed for patients suspected of suffering from nervous system disorders which are of autoimmune origin.
N-methyl-D-aspartate (NMDA) receptor antibodies are associated with the different sub units of the NMDA receptor. Antibodies to the delta or NR2 subunits of NMDA receptor are associated with limbic encephalitis, systemic lupus erythematosus (SLE), ataxia and epilepsia partialis continua. Antibodies against the NR1, NR2A and NR2B subunits of the NMDA are found in patients presenting with psychiatric symptoms, amnesia, seizures, dyskinesias, autonomic dysfunction and loss of consciousness. Also associated with ovarian and testicular teratoma. NMDAR antibody-testing is more sensitive in CSF than serum. Antibody-titers in CSF and serum are higher in patients with poor-outcome or teratoma. The titer-change in CSF correlates better with relapses than that of serum.
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