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Leukemia Panel-AML Mutation, Blood

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Overview

Mutations in the FLT3, NPM1, and CEBPA genes play a crucial role in the development and progression of acute myelogenous leukaemia (AML). The Leukemia Panel-AML Mutation test, performed on blood samples, is designed to detect mutations in the FLT3, NPM1, and CEBPA genes. The assay focuses on these specific genes as they have clinical utility in risk stratification for patients with newly diagnosed cytogenetically normal acute myelogenous leukemia (CN-AML). CN-AML refers to cases where standard cytogenetic analysis does not reveal any chromosomal abnormalities. By analyzing mutations in FLT3, NPM1, and CEBPA, the Leukemia Panel-AML Mutation test aids in determining the risk profile and prognosis for individuals with CN-AML. Mutations in FLT3, such as internal tandem duplications (ITD), are associated with a poor prognosis, while NPM1 and CEBPA mutations are considered favorable prognostic markers. This information helps healthcare professionals in making informed treatment decisions and selecting appropriate therapeutic strategies for CN-AML patients, ultimately improving patient outcomes.

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Leukemia Panel-AML Mutation, Blood Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Leukemia Panel-AML Mutation, Blood with a clear pricing structure.

The Leukemia Panel-AML Mutation, Blood Price in Mira Road is ₹ 12,400 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

The Leukaemia Panel - AML Mutation test detects mutations in the FLT3, NPM1, and CEBPA genes.

• To assess the risk stratification of patients with newly diagnosed cytogenetically normal acute myelogenous leukaemia (CN-AML) • To guide treatment decisions based on the specific mutations present • To aid in prognosis determination for better patient management

• Leukaemia Panel - AML Mutation is recommended for patients with newly diagnosed CN-AML. • The test is suitable for individuals with symptoms suggestive of AML or those who require an accurate prognosis for appropriate management.

Abnormal results of the Leukaemia Panel - AML Mutation may indicate the presence of specific gene mutations associated with AML.

During the test, a small amount of blood will be drawn from a vein in your arm. The blood sample will be sent to the laboratory for analysis.

• Inform your doctor about any medications you are taking. Also, tell them if you have any specific requirements. • Provide a clinical diagnosis, test prescription, and details of the referring clinician for accurate reporting.

• Complete Blood Count (CBC) to evaluate overall blood cell counts • Bone Marrow Aspiration and Biopsy to examine the marrow for cancerous cells • Flow Cytometry to analyse specific proteins on the surface of the leukaemia cells for further classification

AML Gene Mutation Analysis or Acute Myelogenous Leukaemia Mutation Analysis

Acute myelogenous leukaemia is a type of cancer that affects the bone marrow and blood. It is characterised by the rapid growth of abnormal myeloid cells, which are immature blood cells. AML affects the production of healthy blood cells and can lead to symptoms such as fatigue, infections, and bleeding.

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We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

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