Leukemia - Acute Leukemia Panel, Bone Marrow Test
Acute Leukaemia Panel Test Overview
The Acute Leukaemia Panel test is a key diagnostic tool for acute leukaemia, a type of blood cancer with abnormal white blood cell growth. This test uses blood smears and flow cytometry to identify and classify the leukaemia cells in blood or bone marrow. It provides vital data for accurate diagnosis and treatment planning.
The Leukaemia test assesses abnormal cells, helping healthcare providers understand the patient's condition. It is crucial for diagnosing and monitoring acute leukaemia and choosing the best treatment for each patient.
Leukemia also known as blood cancer occurs due to abnormal growth and mutations of the white blood cells. This mutation majorly occurs in the bone marrow, but may be seen in the peripheral blood as well. Leukemia cells majorly behave like abnormal WBCs or platelets. The leukemia panel-Bone marrow comprises of morphological examination of the bone marrow cells followed by Flow cytometry for Imunophenotyping of leukemic cells. This helps in the diagnosis and further classification of leukemia into the specific type.
Written by - Dr.Shibani R ,Medical Writer, Medical Affairs
Reasons for Undergoing the Acute Leukaemia Panel Test
There are several reasons why a doctor may recommend the Leukaemia test:
- To diagnose and classify acute leukaemia when symptoms such as fatigue, easy tiredness, unexplained weight loss, frequent infections, fever, bone or joint pain, and easy bleeding or bruising are present.
- When abnormalities are detected in routine blood examinations (Complete Blood Count - CBC) along with other investigations.
- To determine the type of leukaemia or lymphoma, which is crucial for selecting the most appropriate treatment plan.
- To monitor the patient's condition and assess the effectiveness of the chosen treatment line.
List of Parameters Considered During the Acute Leukaemia Panel Test
The Leukaemia test measures several key parameters to provide a comprehensive assessment of the patient's condition:
- Morphological Examination of Blood Smear: This includes a differential count of various blood cells (blasts, neutrophils, lymphocytes, eosinophils percentage) and an examination of RBC structure and platelets. This helps in identifying the presence of abnormal cells and their distribution.
- Flow Cytometric Analysis: Immunophenotyping of leukaemic cells is performed to identify Lymphoid T cells, Lymphoid B cells, Myeloid cells, and Monocytic cells. This analysis indicates the specific type of leukaemia, such as B-Cell Acute Lymphoblastic Leukaemia (B-ALL) or Acute Myeloid Leukaemia (AML).
Acute Leukaemia Panel Test Preparation
Preparing for the Leukaemia test involves the following steps:
- Blood Sample Collection: A blood sample is collected from a vein, typically from the upper arm. A tourniquet is applied, and the skin is disinfected before needle insertion.
- Medical History: Providing hematopathological reports and a complete medical history is essential for accurate interpretation of the test results.
- No Specific Fasting Requirements: Generally, no fasting is required for this test, making it convenient for patients.
- Comfort and Hydration: Patients should be comfortable and well-hydrated during the test to ensure a smooth sample collection process.
Acute Leukaemia Panel Test Results & Interpretation
The results of the Leukaemia test are interpreted as follows:
- Presence of Leukaemic Cells: The morphological examination and flow cytometric analysis will indicate the presence and type of leukaemic cells, providing a clear picture of the patient's condition.
- Classification of Leukaemia: The test results will help classify leukaemia into specific types such as AML, B-ALL, or other acute leukaemias, which is crucial for determining the most appropriate treatment plan.
- Prognostic Factors: The test may also reveal genetic mutations and other prognostic factors that indicate the aggressiveness of the cancer and guide treatment decisions, helping healthcare providers tailor their approach to each individual patient.
Home Collection for Acute Leukaemia Panel Test Near You
Metropolis Healthcare provides a convenient home sample collection for the Acute Leukaemia Panel Test. Patients can have this crucial Leukaemia test at home with full safety.
A trained phlebotomist visits to collect blood samples, upholding the highest standards of accuracy and handling. This service delivers timely and reliable results, showing Metropolis Healthcare's dedication to accessible, quality diagnostics at home.
Leukemia - Acute Leukemia Panel, Bone Marrow Test Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Leukemia - Acute Leukemia Panel, Bone Marrow Test with a clear pricing structure.
The Leukemia - Acute Leukemia Panel, Bone Marrow Test Price in Mumbai is ₹ 11,130 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
The Leukemia panel consists of morphological examination of EDTA and heparin bone marrow and flow cytometric analysis of Lymphoid T cells, Lymphoid B cells, Myeloid and Monocytic cells.
- In case of abnormalities detected in the routine blood examination (CBC) along with other investigations, the Leukemia panel may be useful for further diagnosis.
- The test is done in patients in whom leukemia or lymphoma is suspected.
- To find out the type of leukemia or lymphoma
- This panel aids proper diagnosis, helps in choosing the right treatment line and monitoring of the patient.
Morphological examination of bone marrow for Differential count, blasts, neutrophils, lymphocytes, eosinophils percentage, RBC structure and platelets examination is done.
The leukemia cells may continue to multiply and develop into Lymphoid T cells, Lymphoid B cells, Myeloid and Monocytic cells.
Leukemia may often be asymptomatic in the early stages. People with following clinical signs should however, undergo the test:
- Fatigue, easy tiredness
- Unexplained weight loss
- Frequent infections, fever
- Bone or joint pain and tenderness
- Easy bleeding or bruising with red spots or purplish discoloration.
This test requires bone marrow sample along with whole blood smear. A small incision is made on the skin, and a hollow needle is inserted from the bone up to the bone marrow to collect the bone marrow sample. The skin is disinfected before needle insertion and the sample is collected in vacutainer.
Medical history / Heamato-pathological reports is required.
The immunophenotyping of leukemic cells in the bone marrow shows differential count of various blood cells.
Based on the differential count percentage, diagnosis of leukemia and its type can be made.
The positivity percentage of Lymphoid T cells, Lymphoid B cells, Myeloid cells and Monocytic cells is further indicative of the Leukemia diagnosis and its respective classification.eg. B - Cell Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia.
- Leukemia Test
- Bone marrow examination test
- Flow cytometry test
Acute Leukaemia Panel test is a comprehensive diagnostic test combines morphological examination of blood smears and flow cytometric analysis to detect and classify acute leukaemia, a type of blood cancer characterised by the abnormal growth and mutation of white blood cells.
Yes, home sample collection is available for the Leukaemia test. A trained phlebotomist can collect blood samples at your home.
The Leukaemia test is used to diagnose and classify acute leukaemia, determine the appropriate treatment plan, and monitor the patient's condition. It helps healthcare providers make informed decisions about the management of blood cancer.
There is no "normal range" for the Leukaemia test as it is a diagnostic test. The presence and type of abnormal cells indicate the diagnosis of leukaemia, and the results are interpreted by qualified healthcare professionals.
Patients suspected of having leukaemia or lymphoma, those with symptoms indicative of leukaemia (such as fatigue, unexplained weight loss, frequent infections, and easy bleeding or bruising), and those with abnormalities in routine blood examinations are eligible for the Acute Leukaemia Panel test.
The benefits of the Leukaemia test include accurate diagnosis, classification of leukaemia, guidance for treatment planning, and monitoring of the disease. It helps healthcare providers make informed decisions and tailor treatment plans to the specific type of leukaemia.
The testing frequency for the Leukaemia test is determined by the healthcare provider based on the patient's condition and treatment plan. It may be done at regular intervals to monitor the progress of the disease and the effectiveness of treatment.
There is no specific time requirement for the Leukaemia test; it can be done at any time as per the healthcare provider's schedule. The test is typically performed when symptoms or abnormalities in routine blood tests suggest the possibility of leukaemia.
Generally, no fasting is required for Leukaemia test. However, it is always best to follow the specific instructions provided by your healthcare provider or the diagnostic laboratory.
Patients should provide a complete medical history and any relevant hematopathological reports to their healthcare provider. No other specific precautions are typically necessary before undergoing the Leukaemia test.
The Leukaemia test includes morphological examination of blood smears and flow cytometric analysis of Lymphoid T cells, Lymphoid B cells, Myeloid cells, and Monocytic cells. These parameters help in the accurate diagnosis and classification of acute leukaemia.
The Leukaemia test involves collecting a blood sample, performing a morphological examination of the blood smear, and conducting flow cytometric analysis. The blood sample is typically drawn from a vein in the arm, and the analysis is performed in a specialised laboratory.
The Leukaemia test should be done when symptoms suggestive of leukaemia are present, such as fatigue, unexplained weight loss, frequent infections, and easy bleeding or bruising. It may also be recommended when abnormalities are detected in routine blood examinations.
The Leukaemia test becomes positive when it detects the presence of leukaemic cells and specific markers indicative of acute leukaemia. The test results are interpreted by qualified healthcare professionals to determine the specific type of leukaemia.
The actual test procedure for the Leukaemia test is quick, and it may only take about 2 to 10 minutes for the blood sample collection.
The reports for the Leukaemia test are usually available within 24 hours, depending on the lab's turnaround time. Your healthcare provider will inform you about the expected timeline for receiving the results.
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