Iron, 24 Hour Urine

This test evaluates the quantity of iron eliminated in the urine over a 24-hour period.

The Iron, 24 Hour Urine test is done to:

• Help diagnose iron overload, which is a condition in which there is too much iron in the blood.
• Monitor the response to treatment for iron overload.
• Evaluate the absorption of iron from the intestines.

• This test is recommended for individuals with suspected iron overload or those with known hemochromatosis.
• It is especially pertinent for individuals undergoing iron-chelation therapy or those with a family history of iron-related disorders.

Abnormal results may indicate excessive iron retention, which can lead to complications. Further evaluation and consultation with a healthcare provider are essential to determine the underlying cause and establish an appropriate course of action.

During the Iron, 24 Hour Urine Test, individuals collect all urine produced over a 24-hour period in a special container provided by the healthcare provider. Proper storage and timely return of the sample are crucial for accurate results.

Patients may receive specific instructions regarding dietary restrictions and medications. It is crucial to follow these guidelines to ensure accurate test results.

Additional tests that may be ordered alongside the Iron, 24 Hour Urine Test include serum iron tests, total iron-binding capacity (TIBC) tests, and ferritin tests. These tests together provide a comprehensive assessment of iron metabolism.

The Iron, 24 Hour Urine Test is sometimes referred to as a

• 24-Hour Urinary Iron Test
• Iron Urine Test

Iron overload, also known as hemochromatosis, can be indicative of several disorders. The primary disorder associated with iron overload is hereditary hemochromatosis, which is a genetic condition. Some other conditions and factors may also lead to iron overload.

1. Hereditary Hemochromatosis: This is a genetic disorder characterized by excessive absorption of dietary iron, leading to its accumulation in various organs, particularly the liver, heart, and pancreas.
2. Secondary Hemochromatosis: Iron overload can also result from other conditions that require frequent blood transfusions or excessive iron intake, such as Thalassemia, Sideroblastic anaemia, Aplastic anaemia, Chronic liver disease, Porphyria cutanea tarda
3. Iron-loading Anaemias: Certain anaemias, such as thalassemia major or sideroblastic anaemia, can lead to iron overload due to the need for frequent blood transfusions.
4. Chronic Liver Disease: Disorders such as alcoholic liver disease and non-alcoholic fatty liver disease can contribute to iron overload, especially when accompanied by repeated liver inflammation and damage.
5. Juvenile Hemochromatosis: This is a rare form of hereditary hemochromatosis that manifests in individuals at a younger age.
6. Repeated Blood Transfusions: Individuals who require frequent blood transfusions, such as those with certain types of anaemia or blood disorders, may accumulate excess iron over time.