DOG-1 IHC

This test detects the presence of a protein marker called DOG-1 in tissue samples. This marker helps in diagnosing and determining the prognosis of certain health conditions.

• To diagnose GISTs and differentiate them from other types of tumours
• To assess the aggressiveness of GISTs and determine treatment options
• To evaluate the effectiveness of targeted therapies for GISTs
• To aid in diagnosing and managing other related tumours

The test may be recommended if you have:

• Suspicion or symptoms of certain types of cancers or tumours
• A previous diagnosis of cancer and need further information for treatment planning
• A need to assess the prognosis or predict the response to therapy

Abnormal results may indicate the presence of certain tumours or cancers. However, abnormal results alone do not provide a definitive diagnosis. Further evaluation, including additional tests and consultation with a specialist, is necessary to determine the exact condition and its implications.

• A small tissue sample will be collected from your body, usually through a biopsy or surgical procedure.
• The sample will be processed and analyzed in the laboratory using immunohistochemistry techniques.
• The presence and distribution of DOG-1 marker in the tissue will be examined to provide diagnostic and prognostic information.

Before undergoing IHC Single Marker with Reporting DOG-1, you will need to:

• Inform your doctor about any medications, herbal supplements, or allergies you have.
• Follow any specific instructions provided by your doctor regarding fasting, medications, or other preparatory measures.
• Provide the original histopathology report, relevant clinical details, and radiological information for accurate interpretation of the test results.

• Molecular testing: This helps identify specific genetic mutations or alterations in cancer cells to guide personalised treatment decisions.
• Imaging studies: CT scans or MRIs help evaluate tumour location and extent.
• Blood tests: To assess tumour markers or other laboratory parameters relevant to the specific condition

• DOG-1 Immunohistochemistry test
• DOG-1 IHC

Gastrointestinal stromal tumour (GIST) is a type of tumour that originates in the digestive tract, mostly in the stomach or small intestine. It can be benign or malignant. GISTs are usually identified by specific markers such as DOG-1 protein and KIT gene mutations.