CK5/6 IHC

This test detects the presence and distribution of CK5/6 protein in tissue samples. CK5/6 is found in cells of certain types of cancers, particularly those affecting the lungs and pleura. Detecting CK5/6 helps pathologists distinguish between different types of cancer cells.

• To differentiate between metastatic carcinoma of the pleura and epithelial mesothelioma
• To aid in diagnosing and staging lung cancer
• To guide treatment decisions based on the specific type of cancer cells present
• To assess the prognosis and predict patient outcomes

This test may be recommended if you:

• Have been diagnosed with lung cancer or pleural tumours
• Show symptoms suggestive of lung or pleural cancers, such as persistent cough, chest pain, or difficulty breathing
• Require further clarification to determine the most appropriate treatment plan

Abnormal results may indicate the presence of metastatic carcinoma of the pleura or epithelial mesothelioma. However, further investigations and consultation with a healthcare professional are required to confirm the diagnosis and discuss appropriate treatment options.

• A small tissue sample will be obtained through a biopsy procedure.
• The sample will be sent to the laboratory for analysis.
• Pathologists will use antibodies to detect the presence and distribution of CK5/6 in the tissue sample.
• Results will be reported after the analysis is completed.

No specific preparations are required for this test. However, you must provide the original histopathology report and all relevant clinical and radiological details to assist with the accurate interpretation of the results. Please speak to your healthcare provider for any specific requirements.

• Histopathology examination to evaluate the overall structure and characteristics of the tissue sample
• Molecular testing to identify specific genetic alterations in the cancer cells
• Imaging tests such as CT scans or PET scans to determine the extent and spread of the cancer

• Immunohistochemistry (IHC) for CK5/6
• CK5/6 staining

Metastatic carcinoma of the pleura refers to cancer that has spread from other organs or tissues to the lining of the lungs (pleura). It is important to distinguish it from primary cancers originating in the pleura, such as epithelial mesothelioma, for appropriate treatment planning.