CD68 IHC

This test measures the expression of CD68 protein in macrophages. The presence of CD68 indicates the presence of macrophages, which are crucial for the body's immune response and play a role in various diseases and conditions.

• To identify and characterize macrophages in tissue samples
• To help diagnose and monitor certain inflammatory diseases, infections, and cancers
• To assess the extent of tumour infiltration by macrophages, which can provide important prognostic information
• To guide treatment decisions and evaluate the effectiveness of therapies targeting macrophages

This test may be recommended if you have:

• Conditions suspected to involve macrophage infiltration, such as infections, inflammatory diseases, or tumors
• Symptoms that suggest macrophage dysfunction, such as recurrent infections or impaired wound healing
• A family history of conditions associated with macrophage abnormalities
• Undergone treatment that affects macrophage function, such as chemotherapy or immunosuppression

Abnormal results could indicate conditions such as inflammation, infections, certain types of cancer or macrophage-mediated tissue damage or repair. It's important to discuss your test results with your doctor, who will evaluate them in the context of your overall health.

• A small tissue sample, typically obtained from a previous biopsy, will be processed and stained for CD68.
• The stained tissue sections will be examined under a microscope to assess the presence and distribution of CD68-positive macrophages.
• The results will be reported by a pathologist and shared with your doctor.

There are no specific preparations required for this test. However, ensure that you provide the original histopathology report and any relevant clinical or radiological details to aid in the interpretation of the test results. Also, speak to your healthcare provider for any specific requirements.

• Additional immunohistochemistry tests to assess the expression of other markers
• Molecular tests to identify specific genetic mutations or alterations
• Biomarker tests to assess the response to targeted therapies or predict prognosis

• Immunohistochemistry for CD68
• CD68 immunostaining
• CD68 antibody staining
• CD68 marker test
• CD68 immunohistochemistry

Macrophage-mediated inflammation refers to an immune response involving macrophages in which these cells play a significant role in causing or perpetuating inflammation. It can occur in various conditions such as infections, autoimmune disorders, and some types of cancer.