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IgE Total Antibody Serum Test

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Total IGE Test Overview

An allergy is a hypersensitivity disorder of the immune system that causes undesirable reactions to certain substances like food, dust, pollen, drugs or even animal dander. These reactions normally do not occur in others. The substance causing the reaction is an allergen. Immunoglobin E is an antibody that the body produces in case of an allergic reaction. Total IgE test is a blood test used to measure the IgE levels in the blood. 

What is an allergy?

An allergy is a hypersensitive disorder. It is caused by the immune system on exposure to allergens such as viruses and bacteria. This makes a person fall sick. However, the immune system may consider a few harmless foreign substances as a threat. These could be pollens, dust, animal dander, certain food and medications, etc. It initiates a defence mechanism against them to protect the body.

During this, the immune system produces a protein called immunoglobulin E (IgE) antibodies. This antibody binds with an antigen. This triggers the other cells in the body to fight the invading antigen. As a result, a person may experience allergic symptoms.

What is the IgE Total Antibody Serum test?

IgE total antibody serum test is a blood test. It is used to find out if a person has developed an allergy. This test measures the total amount of IgE antibodies present in the blood.

Who should take the IgE Total Antibody Serum test?

Your healthcare provider may recommend the IgE total antibody serum test if you have the following allergic symptoms:

  • Itchy or watery eyes
  • Stuffed and runny nose
  • Cough
  • Diarrhoea
  • Vomiting
  • Skin rash
  • Red patches on the skin
  • Wheezing

  • Shortness of breath

Generally, the symptoms are mild. However, in certain cases, the symptoms may turn out to be severe and life-threatening. It is ideal to consult the doctor at the earliest. One should not neglect the symptoms.

Written by: Dr.Shibani R, Medical Writer, Medical Affairs

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IgE Total Antibody Serum Test Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the IgE Total Antibody Serum Test with a clear pricing structure.

The IgE Total Antibody Serum Test Price in Mumbai is ₹ 1,150 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

Total IgE test is done in cases of :

  • Suspected allergies. Common symptoms are: Itching, running nose, sneezing, coughing, diarrhoea, hives
  • Suspected parasitic or fungal infections
  • Certain autoimmune disorders

Total IgE antibody measures the antibody level to IgE in blood serum. Total IgE test only measures the overall component of IgE. Specific IgE test to a specific allergen will help in further diagnosis.

Total ige test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer. 

Elevated levels of IgE indicates presence of parasitic infection, allergy or certain cancers. 
Low levels of IgE are seen in autoimmune diseases
To pin point cause allergen specific IgE and other allergy panels are advised

Allergy can be caused due to various reasons. These could be bacteria, viruses, food, medications, dust, pollen, animal dander, etc.

There is no special preparation for the IgE total antibody serum test.

The IgE total antibody serum test requires a blood sample. An elastic band is placed on the upper arm. After which, a person should make a fist. This is for blood to build up in the veins. The skin is disinfected. Then the needle is inserted into the skin. A small amount of blood is drawn. It is collected in a vial. This blood is then sent to a laboratory for diagnosis.

It is crucial to inform the healthcare provider about all the medications. This is specifically for anti-allergic medications that a person is currently taking. These medications can interfere with the test. This may give a false result.

Generally, IgE is found in very small traces in the blood. Elevated levels of IgE can mean that a person has some kind of allergy. An increase in IgE levels can be due to the following reasons:

  • Allergic conditions such as asthma, urticaria, allergic rhinitis, and atopic dermatitis.
  • Food allergy.
  • Blood-related cancers.
  • Infections such as parasitic infection, HIV, tuberculosis, etc.

In contrast, low levels of IgE indicate autoimmune diseases.

However, this particular test does not pinpoint which specific allergen has caused the allergy. For further diagnosis, the healthcare provider may recommend a specific IgE test.

There is no serious risk with the IgE total antibody serum test. A person may experience a slight swelling, pain or very light bleeding at the site of needle insertion to draw the blood sample.

Sometimes, the IgE total antibody serum test can give a false result. This can be due to a slight reaction of the immune system to a medication. This can also be due to the food taken before the test. However, it is not likely to get a false test, when a person has an allergy.

A skin prick test is done to check for immediate allergic reactions to 50 different substances at once. However, the healthcare provider may recommend a blood test if a person has any skin problems or based on the condition of the person.

Yes, stress increases allergy. During stress, the body releases certain chemicals such as histamines. These cause allergic symptoms. However, stress does not cause allergies. But can worsen the already existing allergic condition.



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