IgG Subclass 3 (IgG3) Serum by Nephelometry

IgG3 Test Overview

The IgG3 test measures the levels of Immunoglobulin G subclass 3 (IgG3) antibodies in the blood. IgG3 makes up about 5-8% of all IgG antibodies, the most common type in human blood. It forms part of the wider immunoglobulin tests that assess immune system function and response to infections or other related conditions.

This test is crucial for understanding the body's immune response. It helps diagnose conditions like immunodeficiency syndromes, recurrent infections, and haemolytic disease of the fetus and newborn (HDFN). By checking IgG3 antibody levels, healthcare professionals can evaluate immune system health and spot any imbalances or abnormalities needing further investigation or treatment.

IgG3 is a specific subclass of immunoglobulin G in your blood that plays a crucial role in immune responses and helps protect against infections. It fights infections by recognising and neutralising pathogens. The IgG3 test is primarily used in the evaluation of patients with clinical signs and symptoms of humoral immunodeficiency or combined immunodeficiency.

To evaluate the overall immunological system and spot specific subclass inadequacies, the IgG3 test is frequently carried out in conjunction with testing for the other IgG subclasses (IgG1, IgG2, and IgG4). IgG subclass levels are evaluated to assist determine the best management and treatment approaches.