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IgG Subclass 3 (IgG3) Serum by Nephelometry
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Blood
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Male, Female
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Blood test at Home
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IgG3 Test Overview
The IgG3 test measures the levels of Immunoglobulin G subclass 3 (IgG3) antibodies in the blood. IgG3 makes up about 5-8% of all IgG antibodies, the most common type in human blood. It forms part of the wider immunoglobulin tests that assess immune system function and response to infections or other related conditions.
This test is crucial for understanding the body's immune response. It helps diagnose conditions like immunodeficiency syndromes, recurrent infections, and haemolytic disease of the fetus and newborn (HDFN). By checking IgG3 antibody levels, healthcare professionals can evaluate immune system health and spot any imbalances or abnormalities needing further investigation or treatment.
IgG3 is a specific subclass of immunoglobulin G in your blood that plays a crucial role in immune responses and helps protect against infections. It fights infections by recognising and neutralising pathogens. The IgG3 test is primarily used in the evaluation of patients with clinical signs and symptoms of humoral immunodeficiency or combined immunodeficiency.
To evaluate the overall immunological system and spot specific subclass inadequacies, the IgG3 test is frequently carried out in conjunction with testing for the other IgG subclasses (IgG1, IgG2, and IgG4). IgG subclass levels are evaluated to assist determine the best management and treatment approaches.
Reasons for Undergoing the IgG3 Test
There are several reasons why a doctor may recommend an IgG3 test:
- Evaluating Immunodeficiency Syndromes: It checks how well the immune system is working. This is useful when an immunodeficiency is suspected.
- Investigating Recurrent Infections: The test is helpful if you frequently get infections like sinusitis or otitis media. It can show if an imbalance in IgG subclasses is causing these infections.
- Assessing the Risk of Haemolytic Disease of the Foetus and Newborn (HDFN): For pregnant women, this test helps gauge the risk and severity of HDFN. IgG3 antibodies can greatly affect this condition.
List of Parameters Considered During the IgG3 Test
The serum IgG3 test measures the concentration of IgG3 antibodies in the blood, typically expressed in milligrams per decilitre (mg/dL). The parameters considered during the test include:
- IgG3 Levels: High levels of IgG3 can indicate an active immune response, possibly due to infections or autoimmune disorders. Low levels suggest immunodeficiency or other conditions affecting antibody production.
- Reference Intervals: The test results are compared against age-specific reference intervals to determine if the IgG3 levels are within the normal range. For example, for adults, the normal range is generally between 15-102 mg/dL.
IgG3 Test Preparation
Preparing for the IgG3 blood test is relatively straightforward:
- No Special Preparation: There is no specific diet or fasting required before the test.
- Inform Your Doctor: It is advisable to inform your doctor about any medications or health conditions you have before undergoing the test.
- Blood Sample Collection: The test involves drawing a blood sample, usually from a vein in the forearm, which is then sent for pathological testing.
IgG3 Test Results & Interpretation
The results of IgG3 test are interpreted based on the measured levels of IgG3 antibodies:
- High Levels: Elevated IgG3 levels can indicate an ongoing infection, autoimmune disorder, or an immune response to certain substances.
- Low Levels: Decreased IgG3 levels may suggest immunodeficiency, protein loss due to disease or trauma, or other conditions affecting antibody production.
- Age-Specific Reference Intervals: The results are compared to age-specific normal ranges to determine if the levels are within the expected range.
Home Collection for IgG3 Test Near You
Metropolis Healthcare provides a home sample collection service for the IgG3 test. This ensures comfort and safety for patients. A trained phlebotomist will come to your home to collect the blood sample. They maintain high standards of sample handling and testing accuracy.
This service lets you get timely and reliable results without sacrificing quality. Metropolis Healthcare aims to make quality diagnostic services more accessible by offering them at home.
IgG Subclass 3 (IgG3) Serum by Nephelometry Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the IgG Subclass 3 (IgG3) Serum by Nephelometry with a clear pricing structure.
The IgG Subclass 3 (IgG3) Serum by Nephelometry Price in Kalamboli is ₹ 5,250 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
This test measures the levels of IgG3 in your blood.
- To evaluate patients with clinical signs and symptoms of humoral immunodeficiency or combined immunodeficiency
- To identify conditions that affect the production or function of IgG3
This test may be recommended if you have
- recurrent or severe infections, especially respiratory or sinus infections,
- autoimmune diseases like lupus or rheumatoid arthritis,
- history of immune system disorders in your family, or
- suspected immune deficiency disorders based on your symptoms and medical history.
Abnormal results, either too high or too low, may indicate immune deficiency disorders, infections, autoimmune diseases, or certain cancers.
A healthcare professional will draw a blood sample from your vein. The sample will be sent to the laboratory for analysis.
- Follow any specific instructions given by your doctor, such as fasting requirements.
- Inform your doctor about any medications you are taking as they may interfere with the test results. Also, tell them if you have any specific requirements.
- Total Immunoglobulin G (IgG) Testing: This test measures the total level of IgG in the blood and helps assess overall immune function.
- Specific Antibody Testing: These tests measure the levels of antibodies against specific pathogens or antigens to determine if you have immunity to certain infections or if your immune system is responding appropriately.
Serum IgG3 by Nephelometry or Quantitative measurement of IgG subclass 3 levels in serum
Humoral immunodeficiency or combined immunodeficiency refers to a group of immune system disorders that affect the body's ability to produce or function properly with antibodies. These conditions can lead to recurrent infections, increased susceptibility to infections, and other complications. Treatment may involve medications, immunoglobulin therapy, and sometimes stem cell transplantation.
The IgG3 test is a blood test that measures the levels of Immunoglobulin G subclass 3 (IgG3) antibodies in blood. It helps assess immune function and response to infections or other immune-related conditions.
Yes, home sample collection is available for the IgG3 test. A trained phlebotomist visits your home to collect the blood sample, ensuring comfort and safety. This service allows for accurate and timely results without compromising on quality.
Normal IgG3 levels vary by age. For adults, the typical range is between 15-102 mg/dL. Age-specific reference intervals are used to determine if the levels are within the expected range.
The IgG3 test is used to evaluate immunodeficiency syndromes, investigate recurrent infections, and assess the risk and severity of the Haemolytic Disease of the Foetus and Newborn (HDFN).
The frequency of the IgG3 test depends on the underlying condition being monitored. Individuals with recurrent infections or those being monitored for immunodeficiency may need periodic testing as advised by their healthcare provider.
There is no specific time requirement for IgG3 test. It is usually conducted during regular clinic hours, following the schedule recommended by your healthcare provider.
No, fasting is not required for the IgG3 blood test. You can undergo the test without any special dietary preparations.
Before the IgG3 test, inform your doctor about any medications or health conditions you have. Ensure the blood sample is collected properly to avoid complications that can affect the test results.
The IgG3 test specifically measures the concentration of IgG3 antibodies in the blood, expressed in milligrams per decilitre (mg/dL). This is the main parameter included in the test.
The igG3 blood test should be done as advised by your healthcare provider, typically when there is a need to evaluate immunodeficiency, investigate recurrent infections, or monitor the risk of HDFN.
The blood collection process for the IgG3 test is quick and typically takes only a few minutes. However, the overall process, including preparation and waiting for the results, may take about an hour or less.
The turnaround time for the serum IgG3 test results is usually within 28 days, based on the day/time when the sample was collected and processed. However, consult with your healthcare provider or the specific lab for more precise timelines.
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