HLA - Single Antigen Bead assay (Class I & Class II) by Bead Based Immnunoassay - Luminex, Serum

Single Antigen Bead Assay (Class I & Class II) is a test that utilizes bead-based technology to detect and quantify specific human leukocyte antigens (HLA) antibodies in a recipient's blood, both in Class I and Class II. The test involves using beads coated with individual HLA antigens from both Class I and Class II. The recipient's serum is incubated with these beads, allowing the antibodies in the serum to bind specifically to their corresponding HLA antigens on the beads. The fluorescence emitted by the bound antibodies is then measured, providing information about the specific HLA antigens to which the recipient has developed antibodies. This comprehensive assay helps evaluate the level of sensitization, determine donor compatibility, and assess the risk of immune-related complications, such as rejection, in organ or tissue transplantation. It assists transplant teams in making informed decisions regarding donor selection, cross-matching, and designing personalized immunosuppressive protocols for optimal transplant outcomes.