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Single Antigen Bead Assay Test (Class I & Class II)

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Single Antigen Bead Assay (Class I & Class II) is a test that utilizes bead-based technology to detect and quantify specific human leukocyte antigens (HLA) antibodies in a recipient's blood, both in Class I and Class II. The test involves using beads coated with individual HLA antigens from both Class I and Class II. The recipient's serum is incubated with these beads, allowing the antibodies in the serum to bind specifically to their corresponding HLA antigens on the beads. The fluorescence emitted by the bound antibodies is then measured, providing information about the specific HLA antigens to which the recipient has developed antibodies. This comprehensive assay helps evaluate the level of sensitization, determine donor compatibility, and assess the risk of immune-related complications, such as rejection, in organ or tissue transplantation. It assists transplant teams in making informed decisions regarding donor selection, cross-matching, and designing personalized immunosuppressive protocols for optimal transplant outcomes.

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Single Antigen Bead Assay Test (Class I & Class II) Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Single Antigen Bead Assay Test (Class I & Class II) with a clear pricing structure.

The Single Antigen Bead Assay Test (Class I & Class II) Price in Mumbai is ₹ 42,800 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

Single Antigen Bead Assay measures specific proteins called Class I & Class II human leukocyte antigens (HLAs) on the surface of cells.

• To assess compatibility between organ donors and recipients prior to transplantation • To identify any potential immune reactions that may occur after transplantation • To guide the selection of suitable donors for individuals requiring organ transplants involving the immune system

The Single Antigen Bead Assay is recommended in the following scenarios: • Prior to organ transplantation to determine compatibility between donors and recipients • For individuals requiring transplants involving the immune system, such as bone marrow or kidney transplants

Abnormal results of the Single Antigen Bead Assay may indicate a higher risk of rejection or immune complications after organ transplantation.

A small blood sample will be collected from your arm. The sample will be sent to a laboratory where it will be analysed using a bead-based immunoassay.

• Provide a complete clinical history and information about the relationship between the recipient and donor. • Ensure that you have the necessary consent forms and any requested photographs ready for submission. • Inform your doctor if you have any specific requirements.

• HLA tissue typing: This test determines human leukocyte antigen (HLA) compatibility between donors and recipients for organ transplantation. • Crossmatch tests: These tests assess compatibility between donor and recipient by checking for pre-existing antibodies in the recipient's blood. • Transplant biopsy: If abnormalities are detected, a biopsy may be performed to further evaluate the transplanted organ.

HLA antibody testing, Donor compatibility testing, or HLA typing

Organ transplantation is a medical procedure in which a diseased or damaged organ is replaced with a healthy organ from a donor. This may be necessary due to organ failure or life-threatening conditions. Transplants can involve organs such as the kidney, liver, heart, lung, pancreas, or bone marrow.

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