Autoimmune Liver Disease Profile - 4

Includes AMA M2, M2-3E (Bpo), Sp100, PML, gp210, LKM1, LC1, SLA / LP, Ro52.

Autoimmune liver disease refers to a group of disorders in which the immune system mistakenly attacks the liver. This results in inflammation and damage to the liver cells, leading to various degrees of liver injury. There are several types of autoimmune liver disease, the most common types are:

• Autoimmune hepatitis (AIH): It is characterized by inflammation and destruction of liver cells, resulting in cirrhosis, jaundice, fatigue, abdominal pain and itchy skin.
• Primary biliary cholangitis (PBC): it is a chronic disease characterized by inflammation and damage of the small bile ducts within the liver. This results in the obstruction of bile flow and eventually leads to cirrhosis, jaundice and itching.
• Primary sclerosing cholangitis (PSC): It is characterized by inflammation and scarring of the bile ducts, both inside and outside the liver, leading to bile duct obstruction, which can result in cirrhosis, jaundice, and itching.

The Autoimmune Liver Disease Profile 4 Test is a comprehensive blood test designed to detect the presence of specific autoantibodies associated with various autoimmune liver diseases. This test helps doctors diagnose and differentiate between conditions such as primary biliary cholangitis (PBC) and autoimmune hepatitis (AIH). By identifying these autoantibodies, the test provides valuable insights into the patient's liver health and immune system function.

The Autoimmune Liver Disease Profile 4 Test includes tests for AMA M2, M2-3E (Bpo), Sp100, PML, gp210, LKM1, LC1, SLA/LP, and Ro52 antibodies. These autoantibodies are specific markers for different types of autoimmune liver diseases, and their presence can help determine the appropriate course of treatment. This test is particularly useful for individuals experiencing symptoms such as abdominal pain, jaundice, itchy skin, and fatigue, which could indicate the presence of an autoimmune liver condition.

Written by : Supriya Kulkarni, Lead-Content & Training