Autoimmune Liver Disease Profile 1 Test

Autoimmune Liver Disease Profile 1 /Autoimmune hepatitis 1 contains ANA, ASMA, LKM1, AMA which Facilitate early diagnosis of autoimmune hepatitis & Primary Biliary Cirrhosis

Autoimmune liver disease refers to a group of disorders in which the immune system mistakenly attacks the liver. This results in inflammation and damage to the liver cells, leading to various degrees of liver injury. There are several types of autoimmune liver disease, the most common types are:

• Autoimmune hepatitis (AIH): It is characterized by inflammation and destruction of liver cells, resulting in cirrhosis, jaundice, fatigue, abdominal pain and itchy skin.
• Primary biliary cholangitis (PBC): it is a chronic disease characterized by inflammation and damage of the small bile ducts within the liver. This results in the obstruction of bile flow and eventually leads to cirrhosis, jaundice and itching.
• Primary sclerosing cholangitis (PSC): It is characterized by inflammation and scarring of the bile ducts, both inside and outside the liver, leading to bile duct obstruction, which can result in cirrhosis, jaundice, and itching.

The Autoimmune Liver Disease Profile 1 Test is a comprehensive blood test designed to aid in the diagnosis and monitoring of autoimmune liver diseases, such as autoimmune hepatitis (AIH) and primary biliary cirrhosis. This specialised profile detects the presence of specific autoantibodies associated with these conditions, providing valuable insights into the patient's liver health and immune system function.

By identifying and measuring the levels of these autoantibodies, the Autoimmune Liver Disease Profile 1 Test helps doctors distinguish between various autoimmune liver disorders and determine the most appropriate course of treatment. This test is particularly useful for patients presenting with symptoms such as abdominal pain, jaundice, fatigue, or those with abnormal liver function tests or features of other autoimmune disorders.

Written by: Supriya Kulkarni, Lead-Content & Training