Ch50 Complement Total Test in Gurgaon - Metropolis Healthcare
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Ch50 Complement Total Test in Gurgaon



CH50 (Complement, Total) Test measures the activity of a set of proteins in the blood.

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    The test is recommended when a person is suffering from any infections, inflammation of unknown origin, autoimmune disorders, is taking treatment for any such immunological disorders. The complement can serve as measure of the immune system activity. In case of persistent microbial infections, the test can give information about the immune system dysfunction-based on low levels of complement. In case of autoimmune disorder, low levels are present as the body consumes the complement without any substantial purpose.

Your doctor would recommend this test for you if you have the following conditions:

  1. Rheumatoid Arthritis 
  2. Kidney Disease
  3. Bacterial Meningitis
  4. Hemolytic uremic syndrome (HUS)

The complement system helps or “complements” augmenting the ability of phagocytes or antibodies to help fight against infections and agents that the body classifies as foreign, “antigen”. It belongs to the immune system and comprises of proteins that are produced in the liver.

However, when the body attacks these “antigens” it creates harm to it’s own tissues, and hence the concentration of this complement should be tightly controlled.  Thus, the proteins which control the level of this complement are always present in a higher amount than the proteins themselves.


Decreased complement levels may be seen with

  1. Recurrent microbial infections (Hereditary complement deficiency predisposes to infections),
  2. Autoimmune diseases (Decreased complement levels are due to increased consumption in autoimmune diseases)
  3. Hereditary angioedema (inflammation and swelling)
  4. Various types of kidney diseases, Serum sickness etc


Increased complement levels are seen during acute or chronic (lasting for a long time usually 6 months or more) inflammation, where high levels are consistently present in order to initiate an immune response.


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Ch50 Complement Total Test