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TSH Receptor Antibody Test
No special precautions
Sample Type
Blood
Recommended for
Male, Female
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Within 24 Hours
Blood test at Home
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TSH Receptor Antibody Test Details in Brief
| Also Known As | TRAb Test, Thyroid-Stimulating Hormone Receptor Antibody Test, Graves’ Disease Antibody Test |
|---|---|
| Purpose | Helps diagnose autoimmune thyroid diseases such as Graves’ disease or Hashimoto’s thyroiditis, monitor treatment response, and assess pregnancy-related thyroid risks |
| Preparation | Avoid high-dose Biotin (>5 mg/day) for at least 8 hours before sample collection |
| Fasting | No fasting required |
| Reporting Time | After 6 hours |
| Cost | 5,030 |
What Is a TSH Receptor Antibody Test?
A TSH Receptor Antibody Test is a blood test that detects antibodies directed against the thyroid-stimulating hormone (TSH) receptor in your thyroid gland. These antibodies can either stimulate or block the receptor, disrupting normal thyroid hormone production.
Doctors primarily use this test to diagnose Graves’ disease (an autoimmune cause of hyperthyroidism), but it can also help detect Hashimoto’s thyroiditis (an autoimmune cause of hypothyroidism). The test helps identify whether your thyroid is overactive or underactive due to an autoimmune process, differentiating it from other thyroid disorders.
The test requires a small blood sample taken from a vein in your arm, and fasting is not needed.
What Does a TSH Receptor Antibody Test Measure?
The TSH Receptor Antibody (TRAb) Test measures specific IgG antibodies that mistakenly attack the TSH receptor on thyroid cells. These antibodies affect thyroid function in two main ways:
- Stimulating antibodies (TSI): Mimic TSH, causing overproduction of thyroid hormones and leading to hyperthyroidism, commonly seen in Graves’ disease.
- Blocking antibodies (TBAb): Inhibit TSH function, reducing thyroid hormone production and contributing to hypothyroidism, as seen in Hashimoto’s thyroiditis.
This test helps your doctor to:
- Confirm autoimmune hyperthyroidism or hypothyroidism.
- Differentiate Graves’ disease from other thyroid disorders.
- Monitor response to antithyroid treatment or radioactive iodine therapy.
- Assess risk of fetal thyroid disease in pregnant women with Graves’ disease.
- Predict relapse or remission after treatment.
TSH Receptor Antibody Test: Who Needs It and Why It’s Done
What Symptoms May Call for a TSH Receptor Antibody Test?
You may need this test if you experience:
- Rapid or irregular heartbeat, palpitations, or trembling hands
- Unexplained weight loss or gain
- Fatigue, muscle weakness, or anxiety
- Increased sensitivity to heat or cold
- Swelling in the neck (goitre)
- Bulging eyes (exophthalmos), a common symptom in Graves’ disease
- Fertility issues or irregular menstrual cycles
Who Should Get a TSH Receptor Antibody Test?
- Have symptoms suggesting hyperthyroidism or hypothyroidism
- Have a family history of autoimmune thyroid disease
- Are being treated for Graves’ disease and need therapy monitoring
- Are pregnant with a history of thyroid disease, to assess fetal risk
- Have inconclusive results from routine thyroid tests (TSH, T3, T4)
Why Is a TSH Receptor Antibody Test Done?
This test helps identify whether thyroid dysfunction is autoimmune in nature and provides guidance for diagnosis, treatment, and monitoring of conditions like Graves’ disease or Hashimoto’s thyroiditis.
Importance of a TSH Receptor Antibody Test
- The TSH Receptor Antibody Test plays a vital role in diagnosing autoimmune thyroid conditions and tailoring treatment plans.
- Detecting elevated antibody levels confirms Graves’ disease early, allowing timely treatment to prevent complications such as heart rhythm problems, bone loss, or thyroid storm.
- In pregnant women, monitoring TRAb levels helps predict and prevent neonatal hyperthyroidism, ensuring maternal and fetal safety.
- Regular testing also assists doctors in tracking recovery and detecting relapses after treatment.
TSH Receptor Antibody Test Booking & Reports – Metropolis Healthcare
How to Book the TSH Receptor Antibody Test and Get Your Reports?
- Simple Online Booking
Book the TSH Receptor Antibody Test easily through the Metropolis Healthcare App or website. Select your preferred time slot and provide your address for home sample collection. You can also visit your nearest Metropolis Lab for in-person testing. - Safe Home Sample Collection
Our experienced phlebotomists collect your blood sample safely from home, following strict hygiene and safety standards. - Sample Tracking Updates
Track your sample status in real-time through the Metropolis Healthcare website or app until your report is ready. - Accurate Laboratory Testing
Your sample is analysed at NABL & CAP accredited Metropolis laboratories using the Electrochemiluminescence Immunoassay (ECLIA) method for precise and reliable results. - Quick & Easy Reports
Receive your test results quickly via email, WhatsApp, or download them directly from the Metropolis Healthcare website or app.
Is Home Sample Collection for TSH Receptor Antibody Test Available Near You?
Yes. Metropolis Healthcare offers doorstep home sample collection for the TSH Receptor Antibody Test. Our skilled phlebotomists ensure safe and convenient blood collection at a time that suits you, eliminating the need for lab visits.
In How Much Time Will I Get TSH Receptor Antibody Test Report?
Reports are usually available within 6 hours once your sample reaches the lab.
Note: Reporting time and cost may vary based on your location.
Where Can I See or Get TSH Receptor Antibody Test Results?
You can view or download your TSH Receptor Antibody Test results from the Metropolis Healthcare website or app. Reports are also shared through email or WhatsApp, and you can collect a printed copy from your nearest Metropolis lab if needed.
Interpreting TSH Receptor Antibody Test Results
What Your TSH Receptor Antibody Test Results May Indicate
| Parameter | Normal Range | High Values May Indicate | Low Values May Indicate |
|---|---|---|---|
| TSH Receptor Antibody (IgG) | Negative: < 1.75 IU/L | Graves’ disease, autoimmune hyperthyroidism, or risk of neonatal hyperthyroidism | Remission or effective treatment response |
Understanding Abnormal TSH Receptor Antibody Test Results by Parameter
| Result Type | Possible Interpretation |
|---|---|
| High TSH Receptor Antibody Levels (>1.75 IU/L) | Suggests active autoimmune thyroid disease such as Graves’ disease or stimulating antibodies causing hyperthyroidism. |
| Low or Negative Levels (<1.75 IU/L) | Indicates remission, treatment success, or non-autoimmune thyroid dysfunction. |
| Moderate Levels | May occur during treatment response or mild autoimmune activity; follow-up testing may be needed. |
How Should You Prepare for a TSH Receptor Antibody Test?
The test requires minimal preparation. To ensure accurate results:
- No fasting required: You can eat and drink normally before the test.
- Avoid Biotin supplements: Stop taking high-dose Biotin (more than 5 mg per day) at least 8 hours before your blood draw.
- Inform your doctor: Let your doctor know about all medications, especially thyroid medicines or steroids.
- Stay relaxed: Get enough rest before testing; stress does not affect antibodies but can make you uneasy.
- Normal hydration: Drink water as usual before your test.
How Is a TSH Receptor Antibody Test Done? (Step-by-Step Procedure)
The test involves a simple blood collection process:
- Preparation: No fasting is needed before the test.
- Cleaning: The puncture site on your arm is cleaned with an antiseptic.
- Blood Draw: A sterile needle is inserted into a vein to collect blood.
- Sample Collection: About 3 ml of blood is drawn into a gel vacutainer.
- Completion: A bandage is applied after removing the needle.
- Processing: The sample is analysed using advanced ECLIA technology for accurate antibody measurement.
Conditions That May Affect TSH Receptor Antibody Test Accuracy
Certain factors may influence your results:
- High-dose Biotin supplements can interfere with immunoassay readings.
- Recent radioiodine therapy or antithyroid drugs can temporarily alter antibody levels.
- Severe illness or pregnancy may cause fluctuations in antibody concentration.
- Incomplete treatment adherence can lead to inconsistent results.
Diseases That a TSH Receptor Antibody Test Can Help Detect
- Graves’ disease (autoimmune hyperthyroidism)
- Hashimoto’s thyroiditis (autoimmune hypothyroidism)
- Autoimmune thyroid dysfunction during pregnancy
- Neonatal hyperthyroidism risk in newborns
- Thyroid-associated ophthalmopathy
TSH Receptor Antibody Test Price in Different Cities
The cost of a TSH Receptor Antibody Test may vary depending on your location. Here's a table showing the approximate price range for the TSH Receptor Antibody Test at Metropolis Healthcare in major Indian cities:
|
City |
Approximate Cost (INR) |
|
₹ 4000 to ₹ 5000 |
|
|
₹ 4000 to ₹ 5000 |
|
|
₹ 4000 to ₹ 5000 |
|
|
₹ 4000 to ₹ 5000 |
TSH Receptor Antibody Test cost may vary depending on the city and the specific tests included in the panel. However, Metropolis Healthcare offers competitive TSH Receptor Antibody Test prices across major cities in India.
References
- Smith, T.J., Hegedüs, L. (2016). Graves’ disease. New England Journal of Medicine, 375(16), 1552–1565. PMID: 27797318
- Laurberg, P., Andersen, S.L. (2015). Therapy of endocrine disease: antithyroid drug use in early pregnancy and birth defects. European Journal of Endocrinology, 173(2), R107–R114. PMID: 25982340
- McLachlan, S.M., Rapoport, B. (2013). Thyrotropin-blocking antibodies and thyroid-stimulating antibodies: potential mechanisms involved in the pendulum swinging from hypothyroidism to hyperthyroidism or vice versa. Thyroid, 23(1), 14–24. PMID: 23025580
- Kahaly, G.J., Bartalena, L., Hegedüs, L. (2018). The European Thyroid Association guideline for Graves’ disease management. European Thyroid Journal, 7(4), 167–186. PMID: 30245764
- Wallach, J. (2014). Interpretation of Diagnostic Tests (10th ed.). Wolters Kluwer Health.
TSH Receptor Antibody Test Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the TSH Receptor Antibody Test with a clear pricing structure.
The TSH Receptor Antibody Test Price in Pune is ₹ 5,030 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
It detects antibodies that affect the thyroid gland’s TSH receptors, helping diagnose autoimmune thyroid disorders such as Graves’ disease or Hashimoto’s thyroiditis.
No, fasting is not required for this test.
Yes. High-dose Biotin can interfere with results. Avoid taking it at least 8 hours before your blood draw.
A small blood sample is taken from a vein in your arm and analysed using the ECLIA method for accurate antibody detection.
High levels indicate Graves’ disease or autoimmune hyperthyroidism. Your doctor will interpret results along with other thyroid tests (TSH, T3, T4).
Reports are generally ready within 6 hours after the sample reaches the laboratory.
A negative result is less than 1.75 IU/L. Values above this suggest active autoimmune thyroid disease.
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Why Metropolis?
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We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
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