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PSA-Total Prostate Specific Antigen Serum Test

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PSA-Total Prostate Specific Antigen Serum Test Details in Brief

Also Known As Total PSA, Serum PSA, Free Prostate-Specific Antigen
Purpose Used for prostate cancer screening and monitoring, helps in risk stratification of prostate cancer, useful in monitoring response to prostate cancer treatment
Preparation Avoid the test for 7 days after PR examination and USG. High biotin doses (>5 mg/day) should be avoided at least 8 hours before blood collection.
Fasting Not required
Reporting Time After 6 hours
Cost 1,000

What Is a PSA-Total Prostate Specific Antigen Serum Test?

A PSA test is a common blood test used primarily to screen for prostate health issues, most notably prostate cancer. The biological sample required for this test is blood, which is drawn from a vein in your arm. This test helps in the early detection of prostate cancer. It can also indicate the presence of non-cancerous conditions such as an enlarged prostate (benign prostatic hyperplasia or BPH) or inflammation of the prostate (prostatitis).

What Does the PSA-Total Prostate Specific Antigen Serum Test Measure?

The purpose of the PSA test is to measure the concentration of a protein called Prostate-Specific Antigen (PSA) in your blood:

• The test measures the level of PSA, a substance made by the prostate gland. Both normal and cancerous prostate cells produce PSA.
• While it is normal for small amounts of PSA to be present in the blood, a higher-than-normal level can be a sign of a prostate problem.
• This test measures the total PSA, which includes two forms of the antigen in the blood: one that is "bound" to other proteins and another that is "free" or unbound.
• Elevated PSA levels are not always due to cancer; benign prostatic hyperplasia (BPH), prostatitis, recent ejaculation, or prostate manipulation can also increase PSA temporarily.

PSA-Total Prostate Specific Antigen Serum Test: Who Needs It and Why It's Done

What Symptoms May Call for a PSA-Total Prostate Specific Antigen Serum Test?

Doctors may recommend a PSA test if you experience symptoms related to urinary or reproductive health, which could indicate a prostate issue:

• Difficulty starting urination or a weak, interrupted flow of urine.
• Needing to urinate frequently, especially at night (a condition called nocturia).
• Feeling pain or a burning sensation during urination.
• Seeing blood in your urine or semen.
• Experiencing pain in the lower back, hips, or pelvic area that does not go away.
• Painful ejaculation

Who Should Get a PSA-Total Prostate Specific Antigen Serum Test?

The PSA test is recommended for specific groups of men after discussing the benefits and limitations with a doctor:

Men with symptoms: Anyone experiencing urinary or reproductive health symptoms.
High-risk individuals: Men with close family relatives who had prostate cancer, especially at a young age.
Age-based screening: Men aged 50 and older for routine screening.
Early screening: Men with a strong family history may start screening at age 40 or 45.
Health checkups: Often included in comprehensive health packages for men over 50.
Treatment monitoring: Men already diagnosed with prostate cancer for treatment monitoring.

Why Is a PSA-Total Prostate Specific Antigen Serum Test Done?

A PSA test is done primarily as a screening tool to detect prostate cancer at an early stage, often before any symptoms appear, when treatment is most effective. It also helps doctors investigate the cause of urinary symptoms and monitor the health of your prostate over time.

Importance of a PSA-Total Prostate Specific Antigen Serum Test

The PSA test is clinically important as a valuable first step in identifying men who may have prostate cancer. Its primary significance lies in its ability to detect cancer early, which significantly improves the chances of successful treatment and long-term survival.

While an elevated PSA level is not a definitive diagnosis of cancer, it serves as a crucial indicator that prompts further investigation through additional tests like a digital rectal exam, an MRI scan, or a prostate biopsy. For patients already diagnosed with prostate cancer, regular PSA testing is essential for monitoring treatment effectiveness and detecting cancer recurrence.

PSA-Total Prostate Specific Antigen Serum Test Booking & Reports – Metropolis Healthcare India

How to Book a PSA-Total Prostate Specific Antigen Serum Test?

  1. Simple Online Booking
    Booking can be done through the Metropolis Healthcare App or website. Select 'PSA-Total Prostate Specific Antigen Serum Test', choose a convenient time slot, and provide your address for a blood test at home. You can also visit the nearest Metropolis Lab if you prefer to give the sample directly at the lab.
  2. Safe Home Sample Collection
    Our trained phlebotomists ensure the timely collection of your sample while strictly following all safety and hygiene protocols.
  3. Sample Tracking Updates
    Stay informed at every step. From collection to testing, you can track your sample directly through the Metropolis Healthcare website.
  4. Accurate Laboratory Testing
    Your sample is processed at our NABL- & CAP-accredited laboratories, where expert technicians ensure accurate results.
  5. Quick & Easy Reports
    Receive your test reports promptly via email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app.

Is Home Sample Collection for the PSA-Total Prostate Specific Antigen Serum Test Available Near You?

Yes, home sample collection for the PSA test is widely available across India through Metropolis Healthcare. Our trained phlebotomists visit your home at your preferred time, following strict safety protocols to collect your blood sample. This service ensures you receive accurate results without the hassle of travelling to a lab.

How Long Does It Take to Get a PSA-Total Prostate Specific Antigen Serum Test Report?

Reports are usually available within 6 hours once the sample reaches the lab.

Where Can I See or Get PSA-Total Prostate Specific Antigen Serum Test Results?

Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis website using your credentials or use the Metropolis Healthcare App to view and download your reports. Additionally, test reports are sent via email or WhatsApp, and you also have the option to collect a physical copy directly from the lab.

Interpreting PSA-Total Prostate Specific Antigen Serum Test Results

What Your PSA-Total Prostate Specific Antigen Serum Test Results May Indicate

The table below shows the reference ranges and what different PSA levels might indicate:

Parameter

Reference Range

High Values May Indicate

Low Values May Indicate

Total PSA (Prostate Specific Antigen)

0 - 4.5 ng/mL (59.1 - 69 years)

Possible prostate cancer, benign prostatic hyperplasia (BPH), prostatitis, or recent prostate examination

Normal prostate fuction or effective response to prostate cancer treatment

 

Conditions That May Affect PSA-Total Prostate Specific Antigen Serum Test Accuracy

Several factors can influence your PSA test results and should be discussed with your doctor:

• A recent prostate examination or digital rectal exam can temporarily raise PSA levels.
• Urological procedures or prostate biopsy within the past few weeks may affect results.
• Certain medications like finasteride or dutasteride can artificially lower PSA levels.
• High-dose biotin supplements (more than 5 mg per day) may interfere with test accuracy.
• Vigorous physical activity, especially cycling, can temporarily raise PSA levels.
• Recent ejaculation may cause a temporary elevation in PSA levels.
• Urinary tract infections or prostate inflammation may cause elevated readings.

How Is a PSA-Total Prostate Specific Antigen Serum Test Done?

The PSA test involves a simple blood draw procedure performed by trained healthcare professionals:

• A healthcare professional cleans an area on your arm with an antiseptic.
• An elastic band is tied around your upper arm to make the vein more visible.
• A small needle is inserted into the vein to collect the blood sample.
• The blood sample is collected in a vial or tube.
• The needle is removed, and a small bandage is applied to the puncture site.
• The entire process takes only a few minutes and causes minimal discomfort.
• Your blood sample is then sent to the laboratory for analysis.

How Should You Prepare for a PSA-Total Prostate Specific Antigen Serum Test?

Proper preparation helps ensure accurate PSA test results:

No fasting required: You can eat and drink normally before the test.
Avoid prostate examination: Refrain from having a digital rectal exam or ultrasound for 7 days before the test.
Limit physical activity: Avoid vigorous exercise, especially cycling, for 48 hours before the test.
Avoid ejaculation: Refrain from sexual activity for 48 hours before the test.
Medication review: Inform your doctor about all medications and supplements you're taking.
Biotin supplements: Stop high-dose biotin (>5 mg/day) at least 8 hours before blood collection.

Diseases that a PSA-Total Prostate Specific Antigen Serum Test Can Help Detect

The PSA test can help identify several prostate-related conditions and assist in ongoing health monitoring:

• Prostate cancer screening and early detection
Benign prostatic hyperplasia (enlarged prostate)
• Prostatitis (prostate inflammation or infection)
• Monitoring response to prostate cancer treatment
• Detecting prostate cancer recurrence after treatment
• Evaluating unexplained pelvic pain related to prostate issues

PSA-Total Prostate Specific Antigen Serum Test/Packages that You Can Book With Metropolis Healthcare

Metropolis Healthcare offers comprehensive prostate health testing options to meet your screening needs:

Test/Package Name

Purpose/Highlights

PSA with Free PSA Ratio Test

Provides additional specificity for distinguishing between benign and malignant prostate conditions.

PSA-Free Prostate Specific Antigen Serum

Measures unbound PSA levels to improve diagnostic accuracy when total PSA is elevated.

Prostate Profile Test

Comprehensive prostate health assessment combining multiple markers for thorough evaluation.

 

PSA-Total Prostate Specific Antigen Serum Test Prices in Different Cities

The PSA test price may vary depending on your location. Here's a table showing the approximate prices in different cities.

City

Price

Mumbai

₹ 700 to ₹ 1200

Delhi

₹ 700 to ₹ 1200

Bengaluru

₹ 700 to ₹ 1200

Chennai

₹ 700 to ₹ 1200

Pune

₹ 700 to ₹ 1200

Ahmedabad

₹ 700 to ₹ 1200

 

Reference:
• Thompson IM, Pauler DK, Goodman PJ, Tangen CM, Lucia MS, Parnes HL, Minasian LM, Ford LG, Lippman SM, Crawford ED, Crowley JJ, Coltman CA Jr. Prevalence of prostate cancer among men with a prostate-specific antigen level < or =4.0ng per milliliter. N Engl J Med. 2004 May 27;350(22):2239-46.
• Arch Pathol Lab Med—Vol 141, November 2017

Read More

PSA-Total Prostate Specific Antigen Serum Test Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the PSA-Total Prostate Specific Antigen Serum Test with a clear pricing structure.

The PSA-Total Prostate Specific Antigen Serum Test Price in Mumbai is ₹ 1,000 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

There is no specific best time of day for a PSA test. However, avoid ejaculation, vigorous exercise like cycling, and digital rectal exams for 48 hours before testing, as these activities can temporarily raise your PSA levels.

No, fasting is not required for a PSA test. You can eat and drink normally before the test, as food intake does not affect PSA levels.

Severe dehydration can make your blood more concentrated, potentially leading to falsely elevated results. It's best to maintain normal hydration before any blood test.

No special diet is needed before a PSA test. However, it's important to inform your doctor about all medications, like finasteride or dutasteride, and supplements you are taking, including biotin, as some can affect PSA test results.

The procedure involves cleaning your arm with an antiseptic, tying an elastic band around your upper arm, inserting a small needle into the vein, and collecting blood in a vial. The entire process takes only a few minutes.

The risks are minimal and similar to any standard blood test. You might experience slight pain, a small bruise at the needle site, or feel dizzy momentarily. Serious complications like infection are very rare.

For men aged 59.1-69 years, the PSA test normal range is 0-4.5 ng/mL. However, doctors consider age, prostate size, and rate of change over time

The PSA test is also known as Total PSA, Serum PSA, or Free Prostate-Specific Antigen when measuring the free component separately. These names refer to the same basic screening test for prostate health.

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