back-arrow-image Search Health Packages, Tests & More

NMDA- CSF & Serum Test

50+ booked in last 3 days

CSF Test Overview

A CSF test is a medical test that measures the levels of cerebrospinal fluid (CSF) in the body. The test is used to diagnose various conditions of the brain and spinal cord. A CSF test is typically done by taking a sample of CSF from the lower back. This is done with a needle and syringe and is usually painless. The sample is then sent to a lab for analysis.

Autoimmune encephalitis is a debilitating inflammatory disorder of the brain causing various neurological signs and symptoms. They often present with seizures and neuropsychiatric symptoms. Apart from the clinical history and presentation, various laboratory tests also supplement and help in diagnosing the condition. NMDA receptor plays a crucial role in regulating a wide variety of neurological functions, including breathing, locomotion, learning, memory formation, and neuroplasticity. Antibodies against glutamate receptor (type NMDA - NR1) are specific markers for inflammatory encephalopathic autoimmune disease.

Total tests included : 1


 Written by : Dr.Shibani R Medical Writer Medical Affairs

Read More

NMDA- CSF & Serum Test Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the NMDA- CSF & Serum Test with a clear pricing structure.

The NMDA- CSF & Serum Test Price in Mumbai is ₹ 11,660 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

Your cerebrospinal fluid can be measured for various chemicals using a CSF analysis. A CSF test is used to diagnose various conditions of the brain and spine.

It might consist of diagnostic tests for the following conditions:

  • Meningitis, encephalitis, and other infectious conditions affect the brain and spinal cord. 
  • Autoimmune diseases like multiple sclerosis and Guillain - Barré syndrome (MS). 
  • Brain tumours, bleeding in the brain, including cancers, migrated to the central nervous system.
  • The most prevalent type of dementia, Alzheimer's disease causes memory loss, confusion, and behavioural problems
  • This test is used in the diagnosis of autoimmune encephalitis.
    NMDA encephalitis is usually diagnosed clinically and the test is often done for confirmation. Symptoms include behavioural disorders (paranoia, hallucination, aggression), memory loss, speech disorder, loss of consciousness, seizures. This may be a result of existing ovarian or testicular teratoma (paraneoplastic syndrome, PNS).

CSF tests are usually performed when there is suspicion of neurodegenerative disease, infection, or inflammation. They can also be used to monitor the progression of certain conditions, such as multiple sclerosis (MS) along with other conditions related to the spinal cord or brain. The test can also be used to help determine the cause of certain types of headaches.

If you are experiencing any of the following symptoms, you should consider getting a CSF test done:

  • severe headaches
  • neck stiffness
  • confusion
  • difficulty waking up
  • seizures
  • vision problems
  • changes in mood or behaviour

If you are having any of these symptoms, it's important to consult with a doctor to see if a CSF test is right for you.

A CSF test is a medical procedure used to collect a sample of cerebrospinal fluid (CSF) that surrounds the brain and spine. This fluid is then analyzed for various proteins, cells, and other markers. The CSF test is a safe and simple procedure that is typically performed in a doctor’s office or hospital. 

During the test, a small amount of CSF is collected through a needle inserted into the lower back. The most common method is a lumbar puncture, also known as a spinal tap. This procedure is generally safe and well-tolerated. However, there are a few potential risks, such as headaches, bleeding, and infection. The sample is then sent to a laboratory for analysis.

This test requires a CSF and blood sample. For the CSF sample, a spinal needle is used and the patient's CSF sample is collected with the necessary aseptic precautions. The test also requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer. 

Most people do not experience any complications from a CSF test. The danger of getting a spinal tap is extremely low. When the needle is inserted, you can feel a slight pressure or pinch. You might experience some discomfort or tightness in your back where the needle was injected for the test.

Additionally, you could get headaches or minor bleeding at the wound. The headache could linger for a few hours or even for a week or longer, but your doctor might recommend treatment to lessen the discomfort.

Normal CSF levels can vary depending on a person's age and health. In general, CSF levels should be between 7 and 50 mg/dL. High levels of CSF may be indicative of a leak, such as a cerebrospinal fluid fistula. Low levels of CSF may be indicative of a blockage, such as a meningeal tumour. The results of a CSF test should be interpreted by a medical professional.

This test detects antibodies against glutamate receptor type NMDA-NR1 in the cerebrospinal fluid [CSF] and blood serum. 

If the NMDA Receptor Antibody (NR1) is detected, it may indicate autoimmune NMDA encephalitis. 
If the test is negative, it does not rule out other forms of autoimmune encephalitis. The results should be correlated with the clinical findings.  

full medical check up

Ratings & Reviews (0)

No reviews available

Why Metropolis?

Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

lab image
170+ Advanced Labs
lab image
Trusted by Leading Doctors & Hospitals
lab images
Over 2000+ Scientific Officers
reports image
Proficiency Testing for Accurate Reports

Latest Blogs & News

View More
View all