Anaemia Profile - Macrocytic

This profile includes CBC, Vitamin B12, Folic acid.

Macrocytic anemia is a blood condition that develops when your bone marrow makes unusually big red blood cells. Red blood cells need certain nutrients to operate correctly, but these aberrant blood cells lack those. It could be brought on by a vitamin deficit or a comorbidity like hypothyroidism. Although macrocytic anaemia is not a serious sickness, it can have serious consequences for your health if you don't address it.

Decrease in hemoglobin level or number of red blood cells (RBC) leads to anaemia. This affect oxygen carrying capacity of blood to various tissues and organs. Commonest cause of anemia is nutritional deficiency of iron, vitamin B12 and folic acid. This can be due to either a lack of these substances in the diet, an increased loss that cannot be compensated by diet alone or an increased unmet demand during pregnancy and lactation.

Few of hereditary haemolytic anaemias include Hemoglobinopathies (Thalassemia's, Sickle cell anaemia etc.), enzyme deficiency disorders (G6PD deficiency). Acquired Haemolytic Anaemias like Autoimmune Haemolytic Anaemias, Microangiopathic haemolytic anaemia are also common in Indian population.

Anaemia Profile- Macrocytic includes both basic & specialised tests to identify macrocytic anaemia and its causes.

Associated Tests:

A0442    Anaemia Profile-Mini

A0441    Anaemia Profile-Maxi

A0440    Anaemia Profile-Haemolytic Type

A0585    Anaemia Profile - Macrocytic

A0586    Anaemia Profile - Microcytic Hypochromic

A0443    Anaemia Profile-Nutritional

A0444    Anaemia Profile-Pernicious

A0587    Anaemia Workup Profile

Written by : Supriya Kulkarni, Lead-Content & Training

Reviewed by :  Dr. Alap Christry M.D. AVP-Lab Operations & Scientific Business Head-Clinical Chemistry