Complement Total Serum CH50 Test in Dahisar

The CH50 test is a laboratory test that measures the total complement activity in serum. A complement is a group of proteins that forms part of the innate immune system. The CH50 test is used to help diagnose and monitor certain autoimmune and inflammatory diseases and is prescribed to assess the effectiveness of the complement system in the body. 

Harmful pathogens that invade the body are eliminated by the immune system with the aid of this mechanism. Several proteins that make up the complement system are secreted by the liver and can be in such abundance that they can account for up to 5% of the globulin fraction in a blood sample.

The complement system is made of proteins which are a part of the immune system. There are close to 30 proteins that work together to protect the body against any infections or diseases. The main function of these proteins is to form antibodies against infections, destroy dead cells, neutralize the virus and bacteria, and build immunity. But at times they may even destroy healthy tissues leading to autoimmune disorders. CH50 serum test is a blood test that detects the overall activity of these proteins, especially the complement activation pathway.

People with the following conditions should go for this test:

• Have butterfly-shaped rashes on their skin
• Suffering from fatigue, mouth sores, and hair loss
• Show sensitivity to sunlight
• Have pain in the joints
• Have chronic fever and heart pain while breathing
• Have lymph nodes that are swollen

Written by: Dr. Shibani R, Medical Writer, Medical Affairs