Do you have any queries?

or Call us now at 9982-782-555

back-arrow-image Search Health Packages, Tests & More

Anti TPO Antibody Test

57+ booked in last 3 days

Anti TPO Antibody Test Details in Brief

Also Known As Microsomal (TPO) Antibody Titre, Thyroid Peroxidase Antibody Test (TPOAb), Thyroid Peroxidase Autoantibodies, Thyroid Microsomal Antibody Test
Purpose Helps diagnose autoimmune thyroid diseases (Hashimoto's and Graves' disease), assists in evaluating thyroid dysfunction, monitors thyroid antibody levels in pregnancy
Preparation No special preparation required
Fasting Not required
Reporting Time After 6 hours
Cost 1,400

What Is an Anti-TPO Test?

An anti-TPO test is a blood test that measures specific antibodies in your blood. TPO stands for thyroid peroxidase, which is an important enzyme found in your thyroid gland that helps produce thyroid hormones. This test helps determine if your body's immune system is mistakenly attacking your thyroid gland, which is a common cause of thyroid-related health conditions.

What Does the Anti-TPO Test Measure?

The anti-TPO test measures several important aspects of your thyroid health:

  • Autoimmune attack detection: The test checks for antibodies that target the thyroid peroxidase enzyme, indicating if your immune system is damaging your thyroid gland
  • Cause of thyroid dysfunction: If other thyroid tests show your thyroid is underactive or overactive, this test helps identify if an autoimmune disease is the underlying cause
  • Hashimoto's thyroiditis diagnosis: High anti-TPO antibody levels are found in about 90% of people with this most common cause of hypothyroidism
  • Graves' disease support: Many people with this hyperthyroidism condition also have elevated anti-TPO levels
  • Disease progression prediction: Positive results in people with mild thyroid problems suggest higher likelihood of developing full hypothyroidism

Anti-TPO Test: Who Needs It and Why It's Done

What Symptoms May Call for an Anti-TPO Test?

Your doctor may recommend this test if you experience symptoms of thyroid dysfunction, which can vary depending on whether your thyroid is underactive or overactive.

Symptoms of hypothyroidism (underactive thyroid):

  • Constant tiredness or fatigue
  • Unexplained weight gain
  • Dry skin and hair loss
  • Feeling cold when others do not
  • Constipation
  • Irregular menstrual periods in women
  • Puffy face and hoarseness of voice
  • Muscle aches and joint pain

Symptoms of hyperthyroidism (overactive thyroid):

  • Unexplained weight loss despite normal appetite
  • Rapid or irregular heartbeat
  • Anxiety, nervousness, and irritability
  • Tremors in hands and fingers
  • Increased sweating and heat sensitivity
  • Frequent bowel movements
  • Enlarged thyroid gland (goitre) in the neck
  • Bulging eyes

Who Should Get an Anti-TPO Test?

Several groups of people may benefit from this test:

  • People with symptoms: Anyone experiencing signs of hypothyroidism or hyperthyroidism
  • Individuals with goitre: If your doctor detects an enlarged thyroid gland during examination
  • High-risk individuals: Those with family history of autoimmune diseases or existing autoimmune conditions like type 1 diabetes
  • Pregnant women: Those with symptoms or history of thyroid issues, as uncontrolled autoimmune thyroid disease can affect both mother and baby
  • Monitoring patients: People with mild thyroid disease to assess their health risk of developing overt hypothyroidism

Why Is an Anti-TPO Test Done?

An anti-TPO test helps find the root cause of thyroid problems. It helps doctors differentiate between autoimmune thyroid disease and other causes of thyroid dysfunction, such as iodine deficiency or viral infections.

Importance of An Anti-TPO Test

The anti-TPO test provides crucial information that goes beyond simply identifying thyroid dysfunction. It confirms specific diagnoses like Hashimoto's thyroiditis, which helps doctors understand that the condition is autoimmune in nature and typically requires lifelong management.

For people with mild thyroid problems, a positive anti-TPO test result suggests a higher likelihood of progression to full hypothyroidism requiring treatment. In pregnant women, identifying autoimmune thyroid disease is particularly important because these antibodies can cross the placenta and potentially affect the baby's thyroid function.

Anti-TPO Test Booking & Reports – Metropolis Healthcare India

How to Book an Anti-TPO Test?

  1. Simple Online Booking
    Booking can be done through the Metropolis Healthcare app or website. Select Anti-TPO Test, choose a convenient time slot, and provide your address for a blood test at home. You can also visit the nearest Metropolis Lab if you prefer to give the sample directly at the lab.
  2. Safe Home Sample Collection
    Our trained phlebotomists ensure timely collection of your sample while strictly following all safety and hygiene protocols.
  3. Sample Tracking Updates
    Stay informed at every step. From collection to testing, you can track your sample directly through the Metropolis Healthcare website.
  4. Accurate Laboratory Testing
    Your sample is processed at our NABL & CAP accredited laboratories, where expert technicians ensure accurate results.
  5. Quick & Easy Reports
    Receive your test reports promptly via email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app.

Is home sample collection for Anti-TPO Test available near you?

Yes, home blood sample collection is available for the anti-TPO test. Our trained phlebotomists follow strict safety protocols while collecting your blood sample in the comfort of your home. This convenient service eliminates the need to visit a pathology lab, saving you time and reducing stress. With Metropolis Healthcare's extensive network of over 10,000+ touchpoints, we ensure reliable, accurate testing reaches you wherever you are.

How Long Does It Take to Get an Anti-TPO Test Report?

Reports are usually available after 6 hours once the sample reaches the lab.

Where can I see or get Anti-TPO Test results?

Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis website using your credentials or use the Metropolis Healthcare app to view and download your reports. Additionally, test reports are sent via email or WhatsApp, and you also have the option to collect a physical copy directly from the lab.

Interpreting Anti-TPO Test Results

What Your Anti-TPO Test Results May Indicate

The following table helps you understand what your anti-TPO test results mean:

Parameter

Reference Range

High Values May Indicate

Low/Normal Values May Indicate

TPO Antibody

< 34.0 IU/mL

Autoimmune thyroid disease (Hashimoto's thyroiditis, Graves' disease), increased risk of thyroid dysfunction, active chronic autoimmune thyroiditis

Normal immune function regarding thyroid, lower risk of autoimmune thyroid disease

 

Conditions that May Affect Anti-TPO Test Accuracy

Several factors can influence your anti-TPO test results and should be discussed with your doctor:

  • Biotin supplements: High doses of biotin (Vitamin B7) can interfere with thyroid hormone tests and may affect results
  • Severe dehydration: Can concentrate blood substances, potentially altering antibody measurements
  • Other autoimmune conditions: Existing autoimmune diseases may influence antibody levels
  • Pregnancy: Can naturally cause elevated anti-TPO antibody levels in some women
  • Recent illness or stress: May temporarily affect immune system function and antibody production
  • Certain medications: Some drugs may influence immune system activity and antibody levels

How is an Anti-TPO Test Done?

The anti-TPO test follows a simple blood collection procedure:

  • A healthcare professional cleans an area on your arm with an antiseptic wipe.
  • An elastic band is tied around your upper arm to make the vein more visible.
  • A small, sterile needle is inserted into the vein to collect blood in a vial.
  • The needle is removed and a cotton ball or bandage is applied to stop bleeding.
  • Your blood sample is sent to the laboratory for analysis using electrochemiluminescence immunoassay technique.

How Should You Prepare for an Anti-TPO Test?

Anti-TPO test preparation is straightforward:

  • No fasting required: You can eat and drink normally before the test
  • Inform about medications: Tell your doctor about all medicines and supplements you're taking
  • Stop biotin supplements: Your doctor may ask you to stop taking biotin for a few days before the test
  • Stay hydrated: Drink adequate water unless your doctor advises otherwise
  • Wear comfortable clothing: Choose clothes that allow easy access to your arm for blood collection

Diseases that an Anti-TPO Test Can Help Detect

The anti-TPO test can help identify several important health conditions:

  • Hashimoto's thyroiditis: The most common cause of hypothyroidism, where immune system gradually destroys thyroid tissue
  • Graves' disease: An autoimmune condition causing hyperthyroidism with overactive thyroid hormone production
  • Autoimmune thyroiditis: Various forms of thyroid inflammation caused by immune system dysfunction
  • Subclinical hypothyroidism: Early stages of thyroid underactivity that may progress to full hypothyroidism
  • Thyroid dysfunction during pregnancy: Autoimmune thyroid problems that can affect both mother and baby

Anti-TPO Test/Packages that You Can Book With Metropolis Healthcare

Related thyroid tests and comprehensive health packages are available to provide complete thyroid health assessment:

Test/Package Name

Purpose/Highlights

Thyroid Antibodies Test

Comprehensive antibody screening for autoimmune thyroid conditions

PTH Intact Molecule Test

Evaluates parathyroid hormone levels related to calcium metabolism

Thyroid Comprehensive Profile Maxi

Complete thyroid function assessment including multiple parameters

 

Anti-TPO Test Prices in Different Cities

The cost of an anti-TPO test may vary depending on your location. Here's a table showing the approximate prices in different cities.

City

Price

Mumbai

₹ 1300 to ₹ 1600

Delhi

₹ 1300 to ₹ 1600

Bengaluru

₹ 1300 to ₹ 1600

Chennai

₹ 1300 to ₹ 1600

Pune

₹ 1300 to ₹ 1600

Ahmedabad

₹ 1300 to ₹ 1600

Read More

Anti TPO Antibody Test Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Anti TPO Antibody Test with a clear pricing structure.

The Anti TPO Antibody Test Price in Noida is ₹ 1,400 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

There is no specific best time of day for the anti-TPO test. Antibody levels remain stable throughout the day, so you can have your blood drawn at any convenient time without worrying about timing affecting your results.

No, fasting is not required for a standalone anti-TPO test. However, if your doctor orders other tests alongside that require fasting, you may need to fast for 8-12 hours. Always confirm fasting requirements with your doctor.

While mild dehydration typically doesn't significantly impact results, severe dehydration can concentrate blood substances, potentially altering antibody measurements. It's best to stay well-hydrated before any blood test unless specifically instructed otherwise by your healthcare provider.

No special diet is needed before the test. However, inform your doctor about all medications and supplements, especially high-dose biotin, which can interfere with thyroid tests and may need to be stopped temporarily.

The procedure involves cleaning your arm, applying an elastic band to make veins visible, inserting a sterile needle to collect blood, and applying a bandage afterward. The entire process takes only a few minutes.

The anti-TPO test has very low risks. You may experience slight pain during needle insertion, minor bruising at the puncture site, or rarely, excessive bleeding, fainting, or infection. These complications are uncommon with proper technique.

Normal anti-TPO antibody levels are typically less than 34.0 IU/mL according to the reference range. Results above this threshold are generally considered positive, indicating the presence of thyroid peroxidase antibodies and possible autoimmune thyroid disease.

The anti-TPO test is also called Thyroid Peroxidase Antibody Test (TPOAb), Thyroid Peroxidase Autoantibodies, Microsomal TPO Antibody Titre, or the older term Thyroid Microsomal Antibody Test. All these names refer to the same diagnostic test.

full medical check up

Ratings & Reviews (0)

No reviews available

Why Metropolis?

Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.

We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

lab image
170+ Advanced Labs
lab image
Trusted by Leading Doctors & Hospitals
lab images
Over 2000+ Scientific Officers
reports image
Proficiency Testing for Accurate Reports

Our Blog

Take a look at some of the related content from our blog

Latest Blogs & News

View More
View all