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TORCH-13 Profile Test

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TORCH Test Overview

Toxoplasma, Rubella, CMV and Herpes are able to pass from mother to child via placenta and cause congenital defects in foetus and may lead to loss of pregnancy. TORCH test is usually performed on the 1st prenatal visit &  later during pregnancy if clinical condition demands to screen for above pathogens. TORCH-13 is a group of tests to detect presence of past or recent infections by i.e., Toxoplasma(T), Rubella(R), Cytomegalovirus(C), Herpes Simplex (H) virus 1 & 2 by detecting IgG & IgM antibodies against them.
In addition, if IgG antibodies are detected against  Toxoplasma, Rubella & CMV then avid antibodies testing is done.

Through the placenta, Toxoplasma, Others (Syphilis, Hepatitis B), Rubella, CMV, and Herpes can be transmitted from mother to kid. The foetus suffers congenital abnormalities as a result. Pregnancy loss could result from this. TORCH testing is often done during the first prenatal appointment. Additionally, it is carried out later in pregnancy. If the clinical condition necessitates testing for the aforementioned infections, this is done.

A series of tests is called TORCH-13. Toxoplasma (T), Rubella (R), Cytomegalovirus (C), and Herpes Simplex (H) viruses 1 and 2 are examples of recent or prior illnesses that can be found using this test. By looking for IgG and IgM antibodies directed against them, it is done. Additionally, avidity testing is conducted for Toxoplasma, Rubella, and CMV in appropriate cases.

Toxoplasma: This parasite infection is known as toxoplasmosis. Uncooked foods like raw milk and eggs are the main culprits. A miscarriage, eyesight loss, seizure disorder, hearing loss, or other birth problems in the foetus can all result from this illness.

Rubella: German measles is another name for rubella. If the virus affects the unborn child while she is still in the womb, it may result in birth defects such as cardiovascular diseases, heart defects, mental retardation, eyesight, hearing, and other problems.

Cytomegalovirus (CMV): Breast milk or the placenta during pregnancy are the two ways that CMV can spread to a kid. In neonates, it may result in epileptic convulsions, mental impairment, hearing difficulties, and other problems.

Herpes Simplex Viruses 1 and 2 (HSV 1 and 2): During delivery, the HSV can infect a newborn as it passes through the birth canal. Infections with HSV 1 and HSV 2 in newborns are typically highly serious. They impact important organs. They harm the central nervous system. They may cause epileptic seizures. They may also affect respiration. Even after antiviral therapy, they may remain.
 

Written by: Dr Vishal Wadhwa, M.D, D.N.B Microbiology, Medical Affairs

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TORCH-13 Profile Test Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the TORCH-13 Profile Test with a clear pricing structure.

The TORCH-13 Profile Test Price in Mumbai is ₹ 3,755 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

TORCH test is done in pregnant females during their first visit to detect their immune status against Toxoplasma, Rubella, CMV and Herpes. A primary infection during pregnancy can lead to transplacental transmission, foetal infection and miscarriage or foetal defects. The risk of foetal defects is highest when the infection is acquired during the first trimester

This test is done in

  • Pregnant females during their first visit. This is done to detect their immune status against Toxoplasma, Rubella, CMV and Herpes.
  • Primary infection during pregnancy can lead to transplacental transmission
  • Foetal infection
  • Miscarriage
  • Foetal defects.

The risk of foetal defects is highest when the infection is acquired during the first trimester. In addition, if not detected on time, it may lead to certain abnormalities in the child. These could be microcephaly (small head circumference), low birth weight, and even problems in vision as well as hearing.

TORCH test measures IgG & IgM antibodies against Toxoplasma, Rubella, CMV and Herpes. If IgG antibodies against toxoplasma, CMV, Rubella are positive then avid antibody test is carried out to detemine time of infection

TORCH test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer

Absence of IgG antibodies suggest lack of immunity/ exposure against these agents. These patients can acquire infection later
If IgG is positive then avidity testing is done to find the apx. time of infection. Avid antibodies take around 6 months to develop

Pregnant women who have been infected with any of the viruses should get the testing done. This is a screening test to ensure the foetus is healthy.

People with the following symptoms should do the TORCH-13 test:

TORCH-13 test needs to be done if the following symptoms appear during pregnancy:

  • Fever
  • Microcephaly (small head circumference)
  • Low birth weight
  • Tiredness
  • Sleepiness or Fatigue
  • Cataracts in the eyes
  • Loss of hearing
  • Heart diseases
  • Liver swelling
  • Reddish brown spots on the skin
  • Yellowing of eyes and skin
  • Bluish rashes on the skin

If you see any of the above symptoms, it is best to get the TORCH-13 test done as soon as possible. Timely detection, as well as treatment, plays a huge role in the prevention of any further complications in the foetus.

A gynaecologist aware of such early monitoring techniques will help in regular monitoring of the foetus during different trimesters of the pregnancy. It has been seen that the first trimester is the most vulnerable to such viral infections.

References:

  1. https://www.1mg.com/labs/test/torch-profile-igg-igm-10-parameters-2568
  2. https://www.osmosis.org/answers/torch-infection

The TORCH - 13 test can be done during each trimester of the pregnancy.

 

No special preparations are required for the test. The doctor needs to be informed of any underlying medical conditions, drugs taken and allergies.

TORCH IgG and IgM Profile

TORCH Profile 13 Parameters

IgG/ IgM Antibodies to Toxoplasma, CMV, Rubella, HSV-1, HSV-2 and Avidity Test for Toxoplasma/ CMV/ Rubella in appropriate cases

TORCH Screen

TORCH Panel

Toxoplasma IgG

Toxoplasma IgM

Rubella IgG

Rubella IgM

Cytomegalovirus (CMV) IgG

Cytomegalovirus (CMV) IgM

Herpes Simplex Virus-1 (HSV-1) IgG

Herpes Simplex Virus-1 (HSV-1) IgM

Herpes Simplex Virus-2 (HSV-2) IgG

Herpes Simplex Virus-2 (HSV-2) IgM

Avidity Testing

full medical check up

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