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TORCH-13 Profile Test

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TORCH-13 Profile Test Details in Brief

Also Known As TORCH 13 Profile, Serum
Purpose To screen for antibodies and avidity markers linked to Toxoplasma, Rubella, CMV, HSV-1 and HSV-2 infections, especially during pregnancy and pre-conception care
Preparation Clinical history required
Fasting Fasting not required
Reporting Time Next day
Cost 3,790

What is the TORCH 13 Profile Test?

The TORCH 13 Profile Test is a blood test that checks for antibodies and avidity markers related to infections that can be important during pregnancy. These include Toxoplasma, Rubella, Cytomegalovirus, Herpes Simplex Virus type 1 and Herpes Simplex Virus type 2.

The test is done using a serum sample, which is the clear liquid part of your blood. It helps your doctor understand whether you may have had a past infection, a possible recent infection, or immunity against certain infections such as Rubella. This information is especially useful during pregnancy, pre-conception planning, infertility evaluation and high risk obstetric care.

What Does a TORCH 13 Profile Test Measure?

The TORCH 13 Profile Test provides detailed information about infection exposure and immune response through 13 parameters:

  • IgG antibodies: Help identify past exposure or immunity to specific infections.
  • IgM antibodies: May suggest a possible recent or current infection, depending on your symptoms and clinical history.
  • Avidity markers: Help your doctor understand whether an infection is likely to be recent or older. Low avidity may suggest recent infection, while high avidity usually points towards past infection.
  • Pregnancy infection risk: Helps assess infections that may affect pregnancy or may be linked with congenital infections in the developing baby.
  • Infection specific status: Checks markers related to Toxoplasma, Rubella, CMV, HSV-1 and HSV-2.

TORCH 13 Profile Test: Who Needs It and Why It’s Done

What Symptoms May Call for a TORCH 13 Profile Test?

Doctors may recommend this test if you have symptoms or pregnancy related concerns that suggest possible infection:

  • Fever, fatigue, body ache or flu-like illness during pregnancy
  • Rash, swollen lymph nodes or recent exposure to a person with infection
  • History of miscarriage, stillbirth or previous pregnancy complications
  • Ultrasound findings that may suggest possible foetal infection
  • Oral blisters, genital sores or symptoms suggestive of herpes infection
  • Suspected exposure to undercooked meat, contaminated food, cat litter or soil, which may increase toxoplasmosis risk

Who Should Get a TORCH 13 Profile Test?

  • Pregnant women who need infection screening as part of high risk pregnancy care
  • Women planning pregnancy, especially if infection immunity needs to be assessed
  • Women with symptoms suggestive of viral or parasitic infection
  • Women with previous pregnancy loss or unexplained obstetric complications
  • Patients undergoing infertility evaluation or reproductive planning
  • Newborns or infants, if the doctor suspects congenital infection and recommends related testing

Why is a TORCH 13 Profile Test Done?

The TORCH 13 Profile Test is done to help detect possible exposure to infections that may affect pregnancy, foetal development or newborn health. It supports your doctor in planning timely follow-up, treatment or monitoring when needed.

Importance of TORCH 13 Profile Test

The TORCH 13 Profile Test is important because many TORCH infections may cause mild symptoms in you but can have serious implications during pregnancy. By checking IgG, IgM and avidity markers together, the test gives your doctor a clearer picture of whether an infection may be old, recent or still uncertain. This helps guide pregnancy monitoring, counselling, treatment decisions and further confirmatory testing when required.

TORCH 13 Profile Test Booking & Reports - Metropolis Healthcare

How to Book the TORCH 13 Profile Test and Get Your Reports?

  1. Simple Online Booking
    Booking can be done through the Metropolis Healthcare App or website. Select the TORCH 13 Profile Test, choose a convenient time slot, and provide your address for a blood test at home. You can also visit the nearest Metropolis Lab if you prefer to give the sample directly at the lab.
  2. Safe Home Sample Collection
    Our trained phlebotomists ensure timely collection of your sample while strictly following all safety and hygiene protocols.
  3. Sample Tracking Updates
    Stay informed at every step. From collection to testing, you can track your sample directly through the Metropolis Healthcare website.
  4. Accurate Laboratory Testing
    Your sample is processed at our NABL and CAP accredited laboratories, where expert technicians ensure accurate results.
  5. Quick and Easy Reports
    Receive your test reports promptly via email, WhatsApp, or by downloading them directly from the Metropolis Healthcare website or app.

Is Home Sample Collection for TORCH 13 Profile Test Available Near You?

Yes, Metropolis Healthcare offers home sample collection for TORCH 13 Profile Test. This service saves you time, reduces the need for travel, and ensures professional sample handling while maintaining strict quality standards. A trained phlebotomist collects your blood sample from your preferred location at your chosen time.

In how much time will I get TORCH 13 Profile Test report?

Reports are usually available the next day once the sample reaches the lab.

Note: Reporting time and cost may vary based on your location.

Where can I see or get TORCH 13 Profile Test results?

Test results from Metropolis Healthcare can be accessed through multiple convenient channels. You can log in to the Metropolis website using your credentials or use the Metropolis Healthcare App to view and download your reports. Additionally, test reports are sent via email or WhatsApp and you also have the option to collect a physical copy directly from the lab.

Interpreting TORCH 13 Profile Test Results

Understanding Abnormal TORCH 13 Profile Test Results by Parameter

Parameter Reference or Interpretive Range Result That Needs Medical Review What It May Mean
Toxoplasma Avidity test Low Avidity: Below 30%, Grayzone avidity: 30 to 35%, High Avidity: Above 35% Low avidity or grayzone avidity May suggest possible recent Toxoplasma infection and may need repeat testing or clinical correlation
Rubella (German measles) virus Avidity test Low Avidity: < 35, Mean Avidity: 35-45, High Avidity: > 45 Low or mean avidity May suggest possible recent Rubella exposure, especially if IgM is also positive
CMV Avidity test Low Avidity: < 30, Greyzone Mean Avidity: 30-40, High Avidity: > 40 Low or greyzone avidity May suggest possible recent CMV infection and needs interpretation with CMV IgG and IgM
HSV-1 (Herpes Simplex Virus-1)IgG antibody Negative: < 14 AU/ml, Equivocal: 14-19 AU/ml, Positive: > 19 AU/ml Positive or equivocal result Positive results may indicate prior exposure to HSV-1
HSV-1 (Herpes Simplex Virus-1)IgM antibody Negative: < 6 AU/ml, Equivocal: 6-10 AU/ml, Positive: > 10 AU/ml Positive or equivocal result May suggest possible acute or recent exposure to HSV-1
HSV-2 (Herpes Simplex Virus-2)IgG antibody Negative: < 9 AU/mL, Equivocal: 9-13 AU/mL, Positive: > 13 AU/mL Positive or equivocal result Positive results may indicate prior exposure to HSV-2
HSV-2 (Herpes Simplex Virus-2)IgM antibody Negative: < 6 AU/ml, Equivocal: 6-10 AU/ml, Positive: > 10 AU/ml Positive or equivocal result May suggest possible acute or recent exposure to HSV-2
Toxoplasma-IgG Antibody Non Reactive: < 1.6 IU/mL, Grayzone: 1.6-3.0 IU/mL, Reactive: >= 3.0 IU/mL Reactive or grayzone result May indicate past exposure to Toxoplasma and should be interpreted with Toxoplasma IgM and avidity
Toxoplasma-IgM Antibody Interpreted as per the reference interval on your report Reactive or borderline result May suggest possible recent Toxoplasma infection and may require repeat testing
CMV IgM antibody Interpreted as per the reference interval on your report Positive or equivocal result May suggest possible recent CMV infection and should be interpreted with CMV IgG and avidity
CMVIgG antibody Interpreted as per the reference interval on your report Positive or equivocal result May indicate past CMV exposure or infection history
Rubella (German measles) virusIgG antibody Interpreted as per the reference interval on your report Negative, equivocal or unexpected result in pregnancy Helps assess Rubella immunity or past exposure
Rubella (German measles) virusIgM antibody Interpreted as per the reference interval on your report Positive or equivocal result May suggest possible recent Rubella infection and needs prompt medical review in pregnancy

How Should You Prepare for a TORCH 13 Profile Test?

The TORCH 13 Profile Test needs minimal preparation. Follow these simple instructions before your blood sample collection:

  • No fasting required: You can eat and drink normally before the test.
  • Normal hydration: Drink water as you usually do so that your blood sample can be collected comfortably.
  • Share pregnancy details: Inform your doctor if you are pregnant, planning pregnancy or undergoing fertility treatment.
  • Provide clinical history: Tell your doctor about fever, rash, swollen glands, blisters, recent infection exposure, previous miscarriage or any abnormal pregnancy scan findings.
  • Discuss vaccination history: Inform your doctor if you recently received Rubella vaccination or any other relevant vaccine.
  • Medication review: Tell your doctor about all medicines, supplements and immune-suppressing treatments you take.
  • Follow medical advice: If your doctor has requested repeat testing after an equivocal result, complete it within the advised time.

How Is a TORCH 13 Profile Test Done? (Step-by-Step Procedure)

The TORCH 13 Profile Test is performed using a simple blood collection process:

  • Preparation: A tourniquet is tied around your arm to make veins more visible.
  • Cleaning: The puncture site is cleaned with antiseptic.
  • Sample Collection: A sterile needle is used to draw about 5 ml of blood into a gel vacutainer.
  • Completion: The needle is removed, and a bandage is applied.
  • Processing: The sample is sent to the laboratory, where serum is separated and tested for TORCH antibodies and avidity markers using the relevant individual test methods.

Conditions That May Affect TORCH 13 Profile Test Accuracy

Several patient related factors can influence how your TORCH 13 Profile Test results are interpreted:

  • Early testing after exposure: Antibodies may not be detectable if your sample is collected too soon after infection. Your doctor may advise repeat testing.
  • Recent vaccination: Rubella antibody results may be influenced by vaccination history, so share this information with your doctor.
  • Past infection or reactivation: Some infections, such as CMV and HSV, can reactivate. Results must be interpreted with your symptoms and history.
  • Weakened immunity: Immune-suppressing medicines or certain health conditions may affect your antibody response.
  • Equivocal results: Borderline results may need repeat testing within 2 to 3 weeks or as advised by your doctor.
  • Missing clinical details: Date of symptom onset, exposure history, pregnancy stage and immunisation history are important for accurate interpretation.

Diseases That a TORCH 13 Profile Test Can Help Detect

The TORCH 13 Profile Test helps your doctor assess infections that may be important during pregnancy and reproductive care:

  • Toxoplasmosis: A parasitic infection that may affect pregnancy if acquired recently.
  • Rubella: Also called German measles, this viral infection can be important during pregnancy due to the risk of congenital rubella.
  • Cytomegalovirus infection: CMV can cause congenital infection if transmitted during pregnancy.
  • Herpes Simplex Virus type 1 infection: HSV-1 may cause oral or genital herpes and can be relevant during pregnancy counselling.
  • Herpes Simplex Virus type 2 infection: HSV-2 is commonly linked with genital herpes and may need special attention during pregnancy.
  • Congenital infection risk: The test supports evaluation when doctors suspect infections that may affect the developing baby.

References

  1. Fitzpatrick D, Holmes NE, Hui L. A systematic review of maternal TORCH serology as a screen for suspected fetal infection. Prenat Diagn. 2022;42(1):87-96. PMID:34893980.
  2. Megli CJ, Coyne CB. Infections at the maternal-fetal interface: an overview of pathogenesis and defence. Nat Rev Microbiol. 2022;20(2):67-82. PMID:34433930.
  3. Rawlinson WD, Boppana SB, Fowler KB, Kimberlin DW, Lazzarotto T, Alain S, et al. Congenital cytomegalovirus infection in pregnancy and the neonate: consensus recommendations for prevention, diagnosis, and therapy. Lancet Infect Dis. 2017;17(6):e177-e188. PMID:28291720.
  4. Teimouri A, Mohtasebi S, Kazemirad E, Keshavarz H. Role of Toxoplasma gondii IgG avidity testing in discriminating between acute and chronic toxoplasmosis in pregnancy. J Clin Microbiol. 2020;58(9):e00505-20. PMID:32321784.
  5. Le Cleach L, Trinquart L, Do G, Maruani A, Lebrun-Vignes B, Ravaud P, et al. Oral antiviral therapy for prevention of genital herpes outbreaks in immunocompetent and nonpregnant patients. Cochrane Database Syst Rev. 2014;(8):CD009036. PMID:25122522.
  6. Hayward I, Copperman TS, Schmid DS, Bialek SR, Cannon MJ. Viral infections in pregnancy: cytomegalovirus, varicella-zoster virus, and herpes simplex virus. Clin Perinatol. 2018;45(2):307-323. PMID:29747888.
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TORCH-13 Profile Test Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the TORCH-13 Profile Test with a clear pricing structure.

The TORCH-13 Profile Test Price in Chennai is ₹ 3,790 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

TORCH test is done in pregnant females during their first visit to detect their immune status against Toxoplasma, Rubella, CMV and Herpes. A primary infection during pregnancy can lead to transplacental transmission, foetal infection and miscarriage or foetal defects. The risk of foetal defects is highest when the infection is acquired during the first trimester

This test is done in

  • Pregnant females during their first visit. This is done to detect their immune status against Toxoplasma, Rubella, CMV and Herpes.
  • Primary infection during pregnancy can lead to transplacental transmission
  • Foetal infection
  • Miscarriage
  • Foetal defects.

The risk of foetal defects is highest when the infection is acquired during the first trimester. In addition, if not detected on time, it may lead to certain abnormalities in the child. These could be microcephaly (small head circumference), low birth weight, and even problems in vision as well as hearing.

TORCH test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer

Absence of IgG antibodies suggest lack of immunity/ exposure against these agents. These patients can acquire infection later
If IgG is positive then avidity testing is done to find the apx. time of infection. Avid antibodies take around 6 months to develop

Pregnant women who have been infected with any of the viruses should get the testing done. This is a screening test to ensure the foetus is healthy.

People with the following symptoms should do the TORCH-13 test:

TORCH-13 test needs to be done if the following symptoms appear during pregnancy:

  • Fever
  • Microcephaly (small head circumference)
  • Low birth weight
  • Tiredness
  • Sleepiness or Fatigue
  • Cataracts in the eyes
  • Loss of hearing
  • Heart diseases
  • Liver swelling
  • Reddish brown spots on the skin
  • Yellowing of eyes and skin
  • Bluish rashes on the skin

If you see any of the above symptoms, it is best to get the TORCH-13 test done as soon as possible. Timely detection, as well as treatment, plays a huge role in the prevention of any further complications in the foetus.

A gynaecologist aware of such early monitoring techniques will help in regular monitoring of the foetus during different trimesters of the pregnancy. It has been seen that the first trimester is the most vulnerable to such viral infections.


The TORCH - 13 test can be done during each trimester of the pregnancy.

 

No special preparations are required for the test. The doctor needs to be informed of any underlying medical conditions, drugs taken and allergies.

TORCH IgG and IgM Profile

TORCH Profile 13 Parameters

IgG/ IgM Antibodies to Toxoplasma, CMV, Rubella, HSV-1, HSV-2 and Avidity Test for Toxoplasma/ CMV/ Rubella in appropriate cases

TORCH Screen

TORCH Panel

Toxoplasma IgG

Toxoplasma IgM

Rubella IgG

Rubella IgM

Cytomegalovirus (CMV) IgG

Cytomegalovirus (CMV) IgM

Herpes Simplex Virus-1 (HSV-1) IgG

Herpes Simplex Virus-1 (HSV-1) IgM

Herpes Simplex Virus-2 (HSV-2) IgG

Herpes Simplex Virus-2 (HSV-2) IgM

Avidity Testing

The TORCH Test is a blood screening test used to detect specific infections that can pose risks to pregnant women and their unborn babies. The acronym "TORCH" stands for Toxoplasmosis, Other infections (like syphilis and varicella), Rubella, Cytomegalovirus (CMV), and Herpes Simplex Virus (HSV). Identifying these infections through the TORCH Test is crucial for managing maternal and fetal health, allowing for timely interventions if necessary. This test is also known as the TORCH panel test or TORCH IgM test.

The TORCH panel test or TORCH blood test is essential for the early detection and treatment of congenital infections that can cause severe complications in newborns. Early diagnosis allows for timely intervention to prevent or mitigate complications like birth defects, growth problems, and organ development issues.

Normal results for the TORCH IgM Test indicate no sign of a current or recent infection. The absence of IgM antibodies suggests the individual does not have an acute infection. Normal value ranges may vary slightly among laboratories.

Common symptoms that may call for a TORCH IgM Test or a TORCH Test include signs of infection in the mother or newborn, such as fever, rash, or specific organ-related symptoms like low birth weight, preterm birth, sores affecting the skin, eyes, and mouth, and brain or organ damage.

A positive TORCH Test indicates the presence of antibodies against one or more of the screened infections. Further testing may be necessary to confirm the diagnosis and develop a treatment plan.

A positive TORCH Test indicates the presence of specific infections that can affect pregnant women and their unborn babies. The acronym "TORCH" stands for Toxoplasmosis, Other (such as syphilis and varicella), Rubella, Cytomegalovirus (CMV), and Herpes Simplex Virus (HSV). These infections can be caused by various pathogens, including parasites, bacteria, and viruses, often transmitted through contaminated food, water, or direct contact. Identifying these infections through the TORCH Test is crucial for managing risks to maternal and foetal health.

If the TORCH Test shows a positive IgG result and a negative IgM result, it typically indicates a past infection rather than a current one. The presence of IgG antibodies suggests that the individual has been exposed to one of the infections, such as Toxoplasmosis, Rubella, or Cytomegalovirus, at some point in their life and has developed immunity.

A negative IgM result indicates the absence of an active infection. This information helps healthcare providers evaluate potential risks during pregnancy and decide whether additional monitoring or intervention is necessary.

The benefits of the TORCH blood test include early detection of congenital infections, prevention of complications, guiding treatment, and providing reassurance when results are negative.

Fasting is not required before taking the TORCH Test. However, it is important to follow any directions provided by the healthcare provider regarding medications, eating, and drinking before the test.

Yes, a home sample collection for the TORCH Test is available at some diagnostic centres, including Metropolis Healthcare. This convenient service enables individuals to have their samples collected at home, providing easy access to the TORCH Test without the need to visit a lab in person.

Generally, TORCH Test reports are available within a week, depending on when the blood sample is collected and processed.

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