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PV Panel (Jak-2 V617F Reflex To Jak-2 Exon 12 Mutation) - Bone Marrow

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Overview

The "PV panel (Jak-2 V617F Reflex to Jak-2 Exon 12 Mutation)-Bone Marrow" test is a diagnostic tool used to investigate suspected cases of Polycythemia Vera (PV) through bone marrow analysis. The test utilizes Real Time PCR and Sanger Sequencing methods to detect specific mutations in the Jak-2 gene. It begins by screening for the Jak-2 V617F mutation, which is commonly associated with PV. If the initial Jak-2 V617F test is negative or inconclusive, a reflex test for Jak-2 Exon 12 Mutation is performed to further investigate the possibility of PV. Detecting these mutations in the bone marrow helps in confirming the diagnosis of PV, a condition characterized by the overproduction of red blood cells, and allows for timely and appropriate management of the disease.
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PV Panel (Jak-2 V617F Reflex To Jak-2 Exon 12 Mutation) - Bone Marrow Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the PV Panel (Jak-2 V617F Reflex To Jak-2 Exon 12 Mutation) - Bone Marrow with a clear pricing structure.

The PV Panel (Jak-2 V617F Reflex To Jak-2 Exon 12 Mutation) - Bone Marrow Price in Mumbai is ₹ 8,480 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

PV Panel screens for the Jak-2 V617F mutation firts. If the initial Jak-2 V617F test is negative or inconclusive, a reflex test for Jak-2 Exon 12 Mutation is performed to further investigate the possibility of PV.
• To detect and confirm cases of Polycythemia Vera • To evaluate patients with symptoms such as excessive red blood cell production, increased blood thickness, and enlarged spleen • To differentiate Polycythemia Vera from other similar conditions
• PV Panel is recommended when Polycythemia Vera is suspected based on symptoms like fatigue, headaches, dizziness, or an enlarged spleen. • People with a family history of Polycythemia Vera or those with unexplained high haemoglobin or hematocrit levels may also be advised to take this test.
An abnormal PV Panel result may indicate the presence of genetic mutations associated with Polycythemia Vera.
During the PV Panel, a healthcare professional will collect a small sample of bone marrow from you after giving you local anaesthesia. They will send the sample to the laboratory for analysis.
• Discuss any medications or supplements you are taking with your doctor, as some may affect the test results. • Inform your doctor if you have any specific requirements.
• Complete Blood Count (CBC): This test helps evaluate the overall composition and health of blood cells • JAK2 Mutation Analysis: Detects a specific genetic mutation commonly associated with Polycythemia Vera • Erythropoietin Level: Measures the hormone erythropoietin, which is involved in red blood cell production
Polycythemia Vera panel or Polycythemia Vera genetic test
Polycythemia Vera is a rare blood disorder characterised by the overproduction of red blood cells in the bone marrow. This leads to an increase in viscosity, which can cause complications such as blood clots, bleeding problems, and an enlarged spleen.
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