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Macroprolactin Test

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Macroprolactin Test Overview

Prolactin is a peptide hormone secreted by pituitary gland . It acts primarily on Mammary glands and its principal action involve - Proliferation of mammary glands ; initiation of milk secretion . The levels of this hormone rises in pregnancy and during lactation. 
Circulating prolactin occurs mainly in three molecular forms: monomeric; “big” & “big, big” also called as macroprolactin. Macroprolactinemia is a frequent cause for mild to moderate hyperprolactinemia but lack symptoms. Hence, patients with hyperprolactinemia should get tested for macroprolactin levels and active prolactin

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Summary Price Of Macroprolactin Test

We are a trusted lab, offering Macroprolactin Test with a transparent pricing structure.

The cost of Macroprolactin Test in India varies as per the city in India.

The average price of Macroprolactin Test ranges from ₹200 to ₹930.

The price for the test in the following cities is:

  • Chennai: ₹900
  • Delhi: ₹900
  • Mumbai: ₹930
  • Pune: ₹900

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Frequently Asked Questions

In patients with moderate increase of Prolactin levels, Macroprolactin test is done. It rules out presence of macroprolactin. Macroprolactin, if present,  does not lead to clinical symptoms and other causes of disease should be investigated. If macroprolactin is absent then symptoms are likely due to high prolactin levels
Reasons for testing prolactin levels are as below:
In non-pregnant women this test is done to investigate women with  menstrual irregularities, infertility and menopausal symptoms. 
In lactating mothers test is also done to investigate cause of abnormal breast milk discharge
In men its is done to evaluate for Lowsex drive , testicular failure or abnormal discharge from breast 
Test is also done to diagnose suspected pituitary tumours, with symptoms of changes in vision and headache

Macroprolactin test measure Prolactin levels in blood of the patient

Macroprolactin test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer.

If monomeric/ active prolactin is  more than 50% then macroprolactin is considered absent and the high results of prolactin should be investigated as below:
High Levels of Prolactin are seen in - Prolactinoma, Polycystic Ovarian Disease, hypothyroidism , liver disease, hypogonadism. Macroprolactinemia must be ruled out. MIld prolactin excess (26.5 to 50 ng/ml) are seen with exercise, lactation, emotional stress, exercise. It may be of no clinical relevance. Repeat test after 1 month is advised. Levels between 51-75 ng/ml are associated with menstrual disorders and subclinical hypothyroidism. Levels above 100 ng/ml are associated with hypogonadism, amenorrhea, galactorrhoea

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