NMO with MOG Antibody Profile for serum Test
₹6500
₹6500
Neuromyelitis Optica is an inflammatory autoimmune disease causing demyelination of the central nervous system with degradation of the insulating sheath of at least one optical nerve (Neuritis nervi optici) and at the same time or few months later the spinal cord (Myelitis).
For Differential diagnosis of NMO from Multiple sclerosis Highly specific serum autoantibody markers are found very frequently in NMO, while they are not detected in Multiple sclerosis (MS) or healthy subjects.
Performed for patients suspected to be suffering from Neuromyelitis optica
Neuromyelitis Optica is an inflammatory autoimmune disease causing demyelination of the central nervous system with degradation of the insulating sheath of at least one optical nerve (Neuritis nervi optici) and at the same time or few months later the spinal cord (Myelitis). NMO AQP4-Ab -are disease specific auto Ab, found in in 70-80% NMO Patients. MOG Antibodies are present in 20% of AQP4 –Seronegative patients with a phenotype of NMOSD (neuromyelitis optica spectrum disorder) MOG antibodies are found in Patients positive for MOG-IgG have a high risk of recurrent disease course
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