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MPO by EIA, p-ANCA Serum Test
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Sample Type
Blood
Recommended for
Male, Female
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Within 24 Hours
Blood test at Home
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MPO by EIA, p-ANCA Serum Test Details in Brief
| Also Known As | MPO-ANCA Test, Myeloperoxidase Antibody Test, p-ANCA Blood Test |
|---|---|
| Purpose | Helps diagnose ANCA-associated vasculitis such as microscopic polyangiitis, Churg–Strauss syndrome, and other autoimmune inflammatory diseases |
| Preparation | No specific preparation required |
| Fasting | Not required |
| Reporting Time | Same day |
| Cost | 1,650 |
What is an MPO by EIA, p-ANCA Serum Test?
The MPO by EIA, p-ANCA Serum Test is a blood test that detects specific antibodies called Myeloperoxidase Antineutrophil Cytoplasmic Antibodies (MPO-ANCA). These are immune system proteins that target and attack your white blood cells, leading to inflammation of small blood vessels, a condition known as vasculitis.
This test helps your doctor diagnose autoimmune conditions such as microscopic polyangiitis (MPA) and eosinophilic granulomatosis with polyangiitis (EGPA), which can affect the kidneys, lungs, and other organs. The sample required for this test is blood collected from a vein in your arm.
What Does an MPO by EIA, p-ANCA Serum Test Measure?
The MPO-ANCA test measures the presence and concentration of antibodies directed against the enzyme myeloperoxidase (MPO) found in white blood cells. It provides valuable insights into:
- Autoimmune Vasculitis Detection: Identifies inflammation caused by the immune system attacking blood vessel walls.
- Disease Differentiation: Helps distinguish between types of ANCA-associated vasculitis such as MPA, GPA, and EGPA.
- Treatment Monitoring: Tracks disease progression and response to immunosuppressive treatment.
- Kidney and Lung Assessment: Detects immune-related injury in organs commonly affected by vasculitis.
MPO by EIA, p-ANCA Serum Test: Who Needs It and Why It’s Done
What Symptoms May Call for an MPO by EIA, p-ANCA Serum Test?
Doctors may recommend this test if you have symptoms suggestive of autoimmune vasculitis, including:
- Unexplained fever, fatigue, or weight loss
- Persistent cough, breathlessness, or chest discomfort
- Blood or protein in urine
- Skin rashes, red spots, or ulcers
- Joint pain, weakness, or nerve pain
Who Should Get an MPO by EIA, p-ANCA Serum Test?
- Individuals showing signs of small-vessel vasculitis or glomerulonephritis
- Patients with suspected autoimmune or inflammatory disorders
- People being monitored for disease recurrence or treatment response
- Individuals with kidney or lung symptoms that cannot be explained by infections
Why is an MPO by EIA, p-ANCA Serum Test Done?
- The test helps confirm a diagnosis of autoimmune vasculitis and distinguish it from other causes of inflammation.
- It also supports disease management by tracking antibody levels during and after treatment.
Importance of an MPO by EIA, p-ANCA Serum Test
- The MPO-ANCA test is an essential diagnostic tool for identifying vasculitis early, preventing organ damage, and guiding treatment decisions.
- By detecting antibodies that attack blood vessels, this test helps doctors tailor immunosuppressive therapy and monitor its effectiveness, improving long-term outcomes.
MPO by EIA, p-ANCA Serum Test Booking & Reports – Metropolis Healthcare
How to Book the MPO by EIA, p-ANCA Serum Test and Get Your Reports?
- Simple Online Booking
You can book your test easily via the Metropolis Healthcare website or app. Select the MPO by EIA, p-ANCA Serum Test, choose your preferred time, and opt for home sample collection. Alternatively, you can visit the nearest Metropolis Lab. - Safe Home Sample Collection
Our trained phlebotomists ensure safe and hygienic sample collection at your doorstep. - Sample Tracking Updates
Track your sample progress at every step on the Metropolis Healthcare website or app. - Accurate Laboratory Testing
Samples are tested in NABL & CAP accredited laboratories using advanced Enzyme Immunoassay (EIA) technology to ensure precision and reliability. - Quick & Easy Reports
Receive your reports via email, WhatsApp, or download them directly from the Metropolis Healthcare app or website.
Is Home Sample Collection for MPO by EIA, p-ANCA Serum Test Available Near You?
Yes. Metropolis Healthcare offers convenient home sample collection. Our experts visit your home at your chosen time, ensuring comfort, accuracy, and strict adherence to safety standards.
In How Much Time Will I Get MPO by EIA, p-ANCA Serum Test Report?
Reports are usually available the same day once the sample reaches the lab.
Note: Reporting time may vary depending on your location.
Where Can I See or Get MPO by EIA, p-ANCA Serum Test Results?
You can access your reports through the Metropolis Healthcare website or mobile app. Reports are also sent to your email and WhatsApp. Physical copies can be collected from the lab if required.
Interpreting MPO by EIA, p-ANCA Serum Test Results
What Your MPO by EIA, p-ANCA Serum Test Results May Indicate
| Parameter | Normal Range | High Values May Indicate | Low/Negative Values May Indicate |
|---|---|---|---|
| MPO – ANCA | < 20 RU/mL | Microscopic polyangiitis, Churg–Strauss syndrome, or autoimmune vasculitis affecting kidneys and lungs | Absence or remission of autoimmune vasculitis |
How Should You Prepare for an MPO by EIA, p-ANCA Serum Test?
Preparing for this test is simple. Follow these easy steps to ensure reliable results:
- No fasting required: You can eat and drink normally before the test.
- Medication review: Inform your doctor about any ongoing medicines or supplements.
- Normal hydration: Stay well hydrated for smoother blood collection.
- Stay calm: Get adequate rest before your appointment.
How Is an MPO by EIA, p-ANCA Serum Test Done? (Step-by-Step Procedure)
The test involves a routine blood collection process:
- Preparation: A band is tied around your upper arm to make veins visible.
- Cleaning: The area is cleaned using an antiseptic.
- Blood Draw: A sterile needle is inserted to collect the sample.
- Sample Collection: Around 3 ml of blood is drawn into a gel vacutainer.
- Completion: The needle is removed, and a small bandage is applied.
- Processing: The sample is analysed in the laboratory using EIA technology.
Conditions That May Affect MPO by EIA, p-ANCA Serum Test Accuracy
Several factors can influence your test results:
- Immunosuppressive medication can lower antibody levels.
- Acute infections or inflammatory diseases can cause temporary fluctuations.
- Recent plasma exchange or immunotherapy may affect antibody detection.
- Improper sample storage or delays in processing can impact accuracy.
Diseases That an MPO by EIA, p-ANCA Serum Test Can Help Detect
- Microscopic Polyangiitis (MPA)
- Eosinophilic Granulomatosis with Polyangiitis (EGPA or Churg–Strauss Syndrome)
- Autoimmune Glomerulonephritis
- Pulmonary–Renal Syndrome
- Systemic Vasculitis
MPO by EIA, p-ANCA Serum Test Price in Different Cities
The cost of a MPO by EIA, p-ANCA Serum Test may vary depending on your location. Here's a table showing the approximate price range for the MPO by EIA, p-ANCA Serum Test at Metropolis Healthcare in major Indian cities:
|
City |
Approximate Cost (INR) |
|
₹ 1500 to ₹ 2000 |
|
|
₹ 1500 to ₹ 2000 |
|
|
₹ 1500 to ₹ 2000 |
|
|
₹ 1500 to ₹ 2000 |
The MPO by EIA, p-ANCA Serum Test cost may vary depending on the city and the specific tests included in the panel. However, Metropolis Healthcare offers competitive MPO by EIA, p-ANCA Serum Test prices across major cities in India.
References
- Jennette J.C., Falk R.J. (2017). Pathogenesis of antineutrophil cytoplasmic autoantibody-mediated disease. Nat Rev Rheumatol, 13(6), 470–479. PMID: 28524174
- Kallenberg C.G.M. (2011). Pathophysiology of ANCA-associated small vessel vasculitis. Curr Rheumatol Rep, 13(6), 512–518. PMID: 21993832
- Millet A., Pederzoli-Ribeil M., Guillevin L., Witko-Sarsat V. (2013). Antineutrophil cytoplasmic antibody-associated vasculitides: Update on pathogenesis. Autoimmun Rev, 12(4), 795–803. PMID: 23384725
- Bosch X., Guilabert A., Espinosa G., Mirapeix E. (2007). Treatment of antineutrophil cytoplasmic antibody associated vasculitis: A systematic review. JAMA, 298(6), 655–669. PMID: 17684188
- Csernok E., Moosig F. (2014). Current and emerging biomarkers in ANCA-associated vasculitis. Nat Rev Rheumatol, 10(8), 494–501. PMID: 24986552
MPO by EIA, p-ANCA Serum Test Price
Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the MPO by EIA, p-ANCA Serum Test with a clear pricing structure.
The MPO by EIA, p-ANCA Serum Test Price in Mumbai is ₹ 1,650 .
We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.
Frequently Asked Questions
A positive MPO-ANCA result suggests the presence of autoimmune vasculitis, most commonly microscopic polyangiitis or eosinophilic granulomatosis with polyangiitis.
No, you can eat and drink normally before the test.
A small blood sample taken from a vein in your arm is used.
Yes, immunosuppressive medicines can reduce antibody levels. Always inform your doctor about your medications before testing.
The test is safe, with minimal discomfort or bruising at the puncture site, which typically resolves quickly.
Your doctor may repeat this test to monitor disease activity and response to treatment.
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Why Metropolis?
Metropolis has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more.
We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.
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