VGKC - CSF & Serum Test in Madurai
Voltage-Gated Potassium Channel (VGKC) antibodies (predominately Anti-LGI1 and Anti-CASPR2) are associated with paraneoplastic neurological syndromes and limbic encephalitis.
For differential diagnosis of Paraneoplastic Neurological Syndrome, Autoimmune Encephalitis, Neuromyotonia.
This test is performed for patients suspected of suffering from nervous system disorders which are of autoimmune origin.
Voltage-Gated Potassium Channel (VGKC) antibodies (predominately Anti-LGI1 and Anti-CASPR2) are associated with paraneoplastic neurological syndromes and limbic encephalitis. These antibodies may also be found in other conditions such as acquired neurmyotonia, painful neuropathy, Morvan's syndrome, and rare tumors (eg, thymoma, small-cell lung cancer). This indirect fluorescent antibody assay utilizes LGI1 and CASPR2 transfected cell lines for the detection and semi-quantification of autoantibodies. Sensitivity is improved when CSF is tested along with serum for detection of antibodies.
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Frequently Asked Questions
Yes our laboratory is accredited by the NABL (National Accreditation Board of Testing and Calibration of Laboratories) India & College of American Pathologists (CAP). This accreditation process is carried out every 2 years for NABL & annually for CAP with periodic internal audits carried out twice in a year. All our aforementioned tests are accredited by NABL & CAP.
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