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Leukemia panels by FISH - Bone Marrow/Leukemic Blood

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Leukemia also known as blood cancer occurs due to abnormal growth and mutations of the white blood cells. This mutation majorly occurs in the bone marrow, but may be seen in the peripheral blood as well. Acute leukaemia leads to the production of blasts or immature WBCs that can interfere with the normal blood cells like RBCs and platelets. The eosinophilia FISH panel is used to aid in the diagnosis of myeloid and lymphoid neoplasms with eosinophilia and prediction of therapeutic response. The clinical and morphologic features can overlap, and each gene rearrangement has a characteristic presentation. 

-Written by - Dr.Shibani R, Medical Writer, Medical Affairs

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Leukemia panels by FISH - Bone Marrow/Leukemic Blood Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the Leukemia panels by FISH - Bone Marrow/Leukemic Blood with a clear pricing structure.

The Leukemia panels by FISH - Bone Marrow/Leukemic Blood Price in Mumbai is ₹ 12,000 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

The Leukemia panels by FISH measures Eosinophilia CBF-Beta, PDGFR-Alpha & beta, FGFR-1 in bone marrow sample.

  • In case of abnormalities (eosinophils) detected in the routine blood examination (CBC) or bone marrow examination along with other investigations, the panel may be useful for further diagnosis.
  • To find out the type of leukaemia based on the genetic mutations.
  • This panel aids proper diagnosis, helps in choosing the right treatment line and monitoring of the patient.
  • Useful to assess the prognosis in leukaemia patients.

Leukemia may often be asymptomatic in the early stages. People with following clinical signs should however, undergo the test:

  • Fatigue, easy tiredness
  • Unexplained weight loss
  • Frequent infections, fever
  • Bone or joint pain and tenderness
  • Easy bleeding or bruising with red spots or purplish discoloration.

This test requires a bone marrow sample. A small incision is made on the skin, and a hollow needle is inserted from the bone up to the bone marrow to collect the bone marrow sample. The skin is disinfected before needle insertion and the sample is collected in vacutainer.

Positive result for FGFR1 (8p21), FIPI-Chic2-PDGFRA and PDGFRB genes indicates mutations or translocations in the respective genes. This aids the diagnosis of Leukaemia and classify into the specific types.

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