Leptospira Profile Test

The Leptospira Profile detects the Leptospira IgG and Leptospira IgM antibodies in the blood serum.

Vast majority of infections are asymptomatic and recover without complications.

• Patients with clinical features of leptospirosis. Clinical spectrum of symptoms varies from mild flu like illness such as fever and myalgia to severe infections characterized by jaundice, renal failure, bleeding and severe pulmonary haemorrhage
• Those with skin rashes
• Patients experiencing diarrhoea, vomiting, abdominal pain.

All these symptoms are mostly accompanied with a history of exposure to infected soil, water, rodents or any animal.

• The test is done in patients in regular contact with animal urine or faeces via soil or water (eg. farmers, veterinarians) and risk of leptospirosis infections
• In those with suspected signs and symptoms of leptospirosis.
• In patients with history of other parasitic or zoonotic infections.
• In those with a history of contact with infected soil or water (e.g. During floods, in hospitals etc)

This test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer.

None.

Leptospira IgM test

Positive result signifies the detection of leptospira IgM antibodies may indicate a recent infection or recent exposure to antigens (vaccine).

Equivocal result indicates that the test needs to be repeated. If results of fresh sample are still equivocal then it is considered negative or should be tested by an alternative/ confirmatory method.

Negative result signifies that Leptospira IgM antibodies are not detected. Since antibodies may not be present or may be present at undetectable levels during early disease, repeat testing of a convalescent sample collected in 2 to 3 weeks is recommended. Negative results do not exclude infection.

Leptospira IgG test

Detection of leptospira IgG antibodies suggests presence of IgG antibodies and may indicate a past infection or convalescence

Equivocal result indicates that the test needs to be repeated. If results of fresh sample are still equivocal then it is considered negative or should be tested by an alternative/ confirmatory method.

Negative result signifies that Leptospira IgG antibodies are not detected. Since antibodies may not be present or may be present at undetectable levels during early disease, repeat testing of a convalescent sample collected in 2 to 3 weeks is recommended. Negative results do not exclude infection.

• Leptospira IgG test
• Leptospira IgM test
• Leptospira detection test

The IgM and IgG tests are used for the qualitative detection of IgM and IgG class of antibodies against Leptospira antigens respectively in the human serum or plasma.