Karyotyping by G-Banding Peripheral Blood Test - Metropolis Healthcare
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Karyotyping by G-Banding Peripheral Blood Test



A karyotype test looks at the size, shape, and number of your chromosomes. 

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    To find chromosome abnormalities, in order to help diagnose genetic diseases, any birth defects, and some disorders of the blood and lymphatic system.

Your doctor would recommend this test if

  1. The foetus is suspected of having a chromosomal abnormality,
  2. If an infant has congenital abnormalities,
  3. If a woman has been experiencing miscarriages or infertility,
  4. When an adult shows signs of a genetic disorder.

Chromosome examination or karyotyping is a test that study the number and shape of a person's chromosomes in order to find abnormalities. Chromosomes are thread-like structures inside each cell nucleus and contain the body's genetic plan. Each chromosome contains thousands of genes in certain locations. These genes are responsible for a person’s congenital physical characteristics and they have a significant impact on growth, development, and functioning of the body.

Humans have 46 chromosomes, present as 23 pairs. 22 pairs are found in both sexes (autosomes) and one pair (sex chromosomes) is present as either XY (in males) or XX (in females). Normally, all cells in the body that have a nucleus will comprise a complete set of the same 46 chromosomes, except for the reproductive cells (eggs and sperm), which contain a half set of 23. This half set is the genetic contribution that will be passed on to a child. At conception, half sets from each parent combine to form a new set of 46 chromosomes in the developing foetus.

A chromosomal karyotyping examines a person's chromosomes to verify if the right number is present and to ascertain if each chromosome appears normal. 

Reference Values Of Karyotyping by G-Banding Peripheral Blood Test

Normal and Abnormal


If your results were show abnormal, it means you or your child has more or less than 46 chromosomes, or there is something irregular about the size, shape, or structure of one or more of the chromosomes. Abnormal chromosomes can cause several health problems. The symptoms and seriousness depend on which chromosomes have been involved.

Some disorders caused by chromosomal defects include:

  • Down syndrome, a disorder that causes intellectual disabilities and developmental delays in children
  • Edwards syndrome, a disorder that causes acute problems in the heart, lungs, and kidneys
  • Turner syndrome, a disorder in girls that influences the development of female characteristics

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Karyotyping by G-Banding Peripheral Blood Test