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JAK2 V617F Mutation Test, With Reflex To Jak2 Ex- 12, CALR Ex-9 Mutation And MPL W515, S505 Mutation

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JAK2 V617F Mutation Test Overview

The JAK2 V617 Mutation test, with reflex to JAK2 Ex-12, CALR Ex-9 Mutation, and MPL W515, S505 Mutation, is a molecular diagnostic test used for the detection of specific mutations associated with myeloproliferative neoplasms (MPNs), including polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). It serves as a molecular marker for MPNs and is particularly useful in suspected cases of PV, ET, or PMF. If the JAK2 V617F mutation is detected, additional mutation analysis for other genes is not necessary as it confirms the presence of an MPN. However, if the JAK2 V617F mutation is not detected, reflex testing for mutations in JAK2 Ex-12, CALR Ex-9, and MPL W515/S505 is performed to explore alternative genetic abnormalities associated with MPNs. This comprehensive molecular testing approach provides valuable information for the diagnosis and classification of MPNs, enabling healthcare professionals to guide appropriate treatment decisions and optimize patient care.

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JAK2 V617F Mutation Test, With Reflex To Jak2 Ex- 12, CALR Ex-9 Mutation And MPL W515, S505 Mutation Price

Metropolis Healthcare is a leading diagnostics centre and pathology lab in India equipped with the latest state-of-the-art technologies that provides the JAK2 V617F Mutation Test, With Reflex To Jak2 Ex- 12, CALR Ex-9 Mutation And MPL W515, S505 Mutation with a clear pricing structure.

The JAK2 V617F Mutation Test, With Reflex To Jak2 Ex- 12, CALR Ex-9 Mutation And MPL W515, S505 Mutation Price in Mumbai is ₹ 13,145 .

We are committed to deliver accurate and quality results from the best labs in India with complete transparency regarding test cost and turnaround time. No matter where you are, we strive to offer patients high-quality service that is affordable and accessible.

Frequently Asked Questions

The JAK2 V617 Mutation Reflex Test detects the presence of a specific mutation in the JAK2 gene.

• To diagnose and confirm MPNs like PV, ET, and PMF • To monitor the progression and response to treatment of MPNs • To rule out other causes of high blood cell counts or abnormal blood cell production

This test is recommended for individuals who • have symptoms suggestive of MPNs like fatigue, enlarged spleen, or abnormal blood counts, • have a suspected diagnosis of PV, ET, or PMF, or • require monitoring of the disease progression or response to treatment.

Abnormal results of the JAK2 V617 Mutation Reflex Test may indicate the presence of the mutation associated with MPNs.

During the test, a technician will collect 3–5 ml of your blood using an EDTA tube. The blood sample will be sent to the laboratory for testing.

• Inform your doctor about any medications you are taking. Also, tell them if you have any specific requirements. • Provide your clinical diagnosis and test prescription and TRF (test request form) for accurate reporting.

• Jak2 Ex-12, MPL W515/S505, CALR Ex-9 Mutation Analysis: These tests confirm the presence of mutations in other genes associated with MPNs. • Complete Blood Count (CBC): This test provides information about red blood cells, white blood cells, and platelets.

JAK2 mutation test or the JAK2 exon 12 mutation test

Myeloproliferative neoplasms are a group of blood disorders characterised by the overproduction of certain blood cells. PV, ET, and PMF are specific types of MPNs. These conditions can affect the normal production and function of blood cells, leading to various symptoms and complications.

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